Gerd Geisslinger

Publications

• PAFAH1B1 and the LncRNA NONHSAT073641 Maintain an Angiogenic Phenotype in Human Endothelial Cells
  Acta Physiologica (Oxford, England). Apr, 2016  |   Pubmed ID: 27124368
• The Impact of Endurance Exercise on Global and AMPK Gene-specific DNA Methylation
  Biochemical and Biophysical Research Communications. Apr, 2016  |   Pubmed ID: 27103439
• Loss of HIF-1α in Macrophages Attenuates AhR/ARNT-mediated Tumorigenesis in a PAH-driven Tumor Model
  Oncotarget. Mar, 2016  |   Pubmed ID: 27015123
• Tetrahydrobiopterin Attenuates DSS-evoked Colitis in Mice by Rebalancing Redox and Lipid Signalling
  Journal of Crohn's & Colitis. Feb, 2016  |   Pubmed ID: 26928964
• The Protein Kinase IKKepsilon Contributes to Tumour Growth and Tumour Pain in a Melanoma Model
  Biochemical Pharmacology. Mar, 2016  |   Pubmed ID: 26793999
• Drug Repurposing for the Development of Novel Analgesics
  Trends in Pharmacological Sciences. Mar, 2016  |   Pubmed ID: 26706620
• Alpha-methylacyl-CoA Racemase Deletion Has Mutually Counteracting Effects on T-cell Responses, Associated with Unchanged Course of EAE
  European Journal of Immunology. Mar, 2016  |   Pubmed ID: 26648339
• Small Molecules with Anti-inflammatory Properties in Clinical Development
  Pharmacology & Therapeutics. Jan, 2016  |   Pubmed ID: 26627986
• S1P2/G12/13 Signaling Negatively Regulates Macrophage Activation and Indirectly Shapes the Atheroprotective B1-Cell Population
  Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2016  |   Pubmed ID: 26603156
• N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators
  Journal of Medicinal Chemistry. Jan, 2016  |   Pubmed ID: 26595749
• In Vivo Availability of Pro-Resolving Lipid Mediators in Oxazolone Induced Dermal Inflammation in the Mouse
  PloS One. 2015  |   Pubmed ID: 26599340
• Age-Dependent Changes in the Inflammatory Nociceptive Behavior of Mice
  International Journal of Molecular Sciences. 2015  |   Pubmed ID: 26593904
• Lipoxin and Resolvin Biosynthesis is Dependent on 5-lipoxygenase Activating Protein
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2015  |   Pubmed ID: 26289316
• AMP-activated Protein Kinase Suppresses Arachidonate 15-lipoxygenase Expression in Interleukin 4-polarized Human Macrophages
  The Journal of Biological Chemistry. Oct, 2015  |   Pubmed ID: 26276392
• The H2S-producing Enzyme CSE is Dispensable for the Processing of Inflammatory and Neuropathic Pain
  Brain Research. Oct, 2015  |   Pubmed ID: 26271715
• Activation of AMPK and Its Impact on Exercise Capacity
  Sports Medicine (Auckland, N.Z.). Nov, 2015  |   Pubmed ID: 26186961
• Rhythmic Control of Endocannabinoids in the Rat Pineal Gland
  Chronobiology International. 2015  |   Pubmed ID: 26061461
• AMP-activated Protein Kinase is Activated by Non-steroidal Anti-inflammatory Drugs
  European Journal of Pharmacology. Sep, 2015  |   Pubmed ID: 26049010
• TANK-binding Kinase 1 (TBK1) Modulates Inflammatory Hyperalgesia by Regulating MAP Kinases and NF-κB Dependent Genes
  Journal of Neuroinflammation. 2015  |   Pubmed ID: 25997745
• Activated Platelets Release Sphingosine 1-phosphate and Induce Hypersensitivity to Noxious Heat Stimuli in Vivo
  Frontiers in Neuroscience. 2015  |   Pubmed ID: 25954148
• MPGES-1-derived PGE2 Suppresses CD80 Expression on Tumor-associated Phagocytes to Inhibit Anti-tumor Immune Responses in Breast Cancer
  Oncotarget. Apr, 2015  |   Pubmed ID: 25871398
• Exacerbation of Experimental Autoimmune Encephalomyelitis in Ceramide Synthase 6 Knockout Mice is Associated with Enhanced Activation/migration of Neutrophils
  Immunology and Cell Biology. Oct, 2015  |   Pubmed ID: 25833068
• Quantitation of Endogenous Nucleoside Triphosphates and Nucleosides in Human Cells by Liquid Chromatography Tandem Mass Spectrometry
  Analytical and Bioanalytical Chemistry. May, 2015  |   Pubmed ID: 25749797
• Antinociceptive Effects of FTY720 During Trauma-induced Neuropathic Pain Are Mediated by Spinal S1P Receptors
  Biological Chemistry. Jun, 2015  |   Pubmed ID: 25720064
• Lack of Ceramide Synthase 2 Suppresses the Development of Experimental Autoimmune Encephalomyelitis by Impairing the Migratory Capacity of Neutrophils
  Brain, Behavior, and Immunity. May, 2015  |   Pubmed ID: 25697397
• Pattern of Neuropathic Pain Induced by Topical Capsaicin Application in Healthy Subjects
  Pain. Mar, 2015  |   Pubmed ID: 25687540
• Slack Channels Expressed in Sensory Neurons Control Neuropathic Pain in Mice
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2015  |   Pubmed ID: 25609627
• Telaprevir Drug Monitoring During Antiviral Therapy of Hepatitis C Graft Infection After Liver Transplantation
  Liver International : Official Journal of the International Association for the Study of the Liver. Jan, 2015  |   Pubmed ID: 24649882
• Regulation of Circulating Endocannabinoids Associated with Cancer and Metastases in Mice and Humans
  Oncoscience. 2014  |   Pubmed ID: 25594019
• Ceramide Synthases CerS4 and CerS5 Are Upregulated by 17β-estradiol and GPER1 Via AP-1 in Human Breast Cancer Cells
  Biochemical Pharmacology. Dec, 2014  |   Pubmed ID: 25451689
• Role of Telaprevir Plasma Levels for Predicting Response to Antiviral Therapy in Patients with Hepatitis C Virus Genotype 1 Infection
  Scandinavian Journal of Gastroenterology. Dec, 2014  |   Pubmed ID: 25384840
• Mechanism-based Treatment for Chemotherapy-induced Peripheral Neuropathic Pain
  Nature Reviews. Neurology. Dec, 2014  |   Pubmed ID: 25366108
• R-flurbiprofen Attenuates Experimental Autoimmune Encephalomyelitis in Mice
  EMBO Molecular Medicine. Nov, 2014  |   Pubmed ID: 25269445
• Regulation of Ceramide Synthase 6 in a Spontaneous Experimental Autoimmune Encephalomyelitis Model is Sex Dependent
  Biochemical Pharmacology. Nov, 2014  |   Pubmed ID: 25173988
• Nox2-dependent Signaling Between Macrophages and Sensory Neurons Contributes to Neuropathic Pain Hypersensitivity
  Pain. Oct, 2014  |   Pubmed ID: 25139590
• Chiral Chromatography-tandem Mass Spectrometry Applied to the Determination of Pro-resolving Lipid Mediators
  Journal of Chromatography. A. Sep, 2014  |   Pubmed ID: 25124229
• Lack of Effect of a P2Y6 Receptor Antagonist on Neuropathic Pain Behavior in Mice
  Pharmacology, Biochemistry, and Behavior. Sep, 2014  |   Pubmed ID: 25042778
• Lipoxin A₄: Problems with Its Determination Using Reversed Phase Chromatography-tandem Mass Spectrometry and Confirmation with Chiral Chromatography
  Talanta. Sep, 2014  |   Pubmed ID: 24913860
• Phosphodiesterase 2A Localized in the Spinal Cord Contributes to Inflammatory Pain Processing
  Anesthesiology. Aug, 2014  |   Pubmed ID: 24758774
• Consequences of a Human TRPA1 Genetic Variant on the Perception of Nociceptive and Olfactory Stimuli
  PloS One. 2014  |   Pubmed ID: 24752136
• Genome-wide Transcriptional Profiling of Skin and Dorsal Root Ganglia After Ultraviolet-B-induced Inflammation
  PloS One. 2014  |   Pubmed ID: 24732968
• LPS Inhibits Caspase 3-dependent Apoptosis in RAW264.7 Macrophages Induced by the AMPK Activator AICAR
  Biochemical and Biophysical Research Communications. May, 2014  |   Pubmed ID: 24732361
• Neutrophils Mediate Edema Formation but Not Mechanical Allodynia During Zymosan-induced Inflammation
  Journal of Leukocyte Biology. Jul, 2014  |   Pubmed ID: 24555986
• Inhibition of Macrophage Fatty Acid β-oxidation Exacerbates Palmitate-induced Inflammatory and Endoplasmic Reticulum Stress Responses
  Diabetologia. May, 2014  |   Pubmed ID: 24488024
• Similar Maximum Systemic but Not Local Cyclooxygenase-2 Inhibition by 50 Mg Lumiracoxib and 90 Mg Etoricoxib: a Randomized Controlled Trial in Healthy Subjects
  Pharmaceutical Research. Jul, 2014  |   Pubmed ID: 24469906
• Oxidant-induced Activation of CGMP-dependent Protein Kinase Iα Mediates Neuropathic Pain After Peripheral Nerve Injury
  Antioxidants & Redox Signaling. Oct, 2014  |   Pubmed ID: 24450940
• PGE2/EP4 Signaling in Peripheral Immune Cells Promotes Development of Experimental Autoimmune Encephalomyelitis
  Biochemical Pharmacology. Feb, 2014  |   Pubmed ID: 24355567
• Prostacyclin Mediates Neuropathic Pain Through Interleukin 1β-expressing Resident Macrophages
  Pain. Mar, 2014  |   Pubmed ID: 24333781
• BKCa Channels Expressed in Sensory Neurons Modulate Inflammatory Pain in Mice
  Pain. Mar, 2014  |   Pubmed ID: 24333777
• TRP-channels As Key Integrators of Lipid Pathways in Nociceptive Neurons
  Progress in Lipid Research. Jan, 2014  |   Pubmed ID: 24287369
• Electrophilic Fatty Acid Species Inhibit 5-lipoxygenase and Attenuate Sepsis-induced Pulmonary Inflammation
  Antioxidants & Redox Signaling. Jun, 2014  |   Pubmed ID: 24206143
• Prostacyclin Regulates Spinal Nociceptive Processing Through Cyclic Adenosine Monophosphate-induced Translocation of Glutamate Receptors
  Anesthesiology. Feb, 2014  |   Pubmed ID: 23969560
• Synthesis of Lipid Mediators During UVB-induced Inflammatory Hyperalgesia in Rats and Mice
  PloS One. 2013  |   Pubmed ID: 24349046
• Synthesis and Pharmacological Characterization of Benzenesulfonamides As Dual Species Inhibitors of Human and Murine MPGES-1
  Bioorganic & Medicinal Chemistry. Dec, 2013  |   Pubmed ID: 24183739
• Common Non-epigenetic Drugs As Epigenetic Modulators
  Trends in Molecular Medicine. Dec, 2013  |   Pubmed ID: 24054876
• Activation of the AMP-activated Protein Kinase Reduces Inflammatory Nociception
  The Journal of Pain : Official Journal of the American Pain Society. Nov, 2013  |   Pubmed ID: 23916727
• Exogenous Delta⁹-tetrahydrocannabinol Influences Circulating Endogenous Cannabinoids in Humans
  Journal of Clinical Psychopharmacology. Oct, 2013  |   Pubmed ID: 23899642
• Ceramide Metabolism in Mouse Tissue
  The International Journal of Biochemistry & Cell Biology. Aug, 2013  |   Pubmed ID: 23792024
• Non-invasive Combined Surrogates of Remifentanil Blood Concentrations with Relevance to Analgesia
  Naunyn-Schmiedeberg's Archives of Pharmacology. Oct, 2013  |   Pubmed ID: 23775505
• Opioids for Chronic Non-cancer Pain
  BMJ (Clinical Research Ed.). 2013  |   Pubmed ID: 23719636
• Cysteinyl Leukotriene-receptor-1 Antagonists Interfere with PGE2 Synthesis by Inhibiting MPGES-1 Activity
  Biochemical Pharmacology. Jul, 2013  |   Pubmed ID: 23684692
• Heterologously Expressed Formyl Peptide Receptor 2 (FPR2/ALX) Does Not Respond to Lipoxin A₄
  Biochemical Pharmacology. Jun, 2013  |   Pubmed ID: 23643932
• Novel Findings in Pain Processing Pathways: Implications for MiRNAs As Future Therapeutic Targets
  Expert Review of Neurotherapeutics. May, 2013  |   Pubmed ID: 23621309
• Proteomics and NF-κB: An update
  Expert Review of Proteomics. Apr, 2013  |   Pubmed ID: 23573785
• Functional Genomics of Pain in Analgesic Drug Development and Therapy
  Pharmacology & Therapeutics. Jul, 2013  |   Pubmed ID: 23567662
• The Equilibrium Between Long and Very Long Chain Ceramides is Important for the Fate of the Cell and Can Be Influenced by Co-expression of CerS
  The International Journal of Biochemistry & Cell Biology. Jul, 2013  |   Pubmed ID: 23538298
• Antioxidant Activity of Sestrin 2 Controls Neuropathic Pain After Peripheral Nerve Injury
  Antioxidants & Redox Signaling. Dec, 2013  |   Pubmed ID: 23495831
• Cannabinoid-mediated Diversity of Antinociceptive Efficacy of Parecoxib in Wistar and Sprague Dawley Rats in the Chronic Constriction Injury Model of Neuropathic Pain
  Naunyn-Schmiedeberg's Archives of Pharmacology. May, 2013  |   Pubmed ID: 23371449
• Modulation of Central Nervous System-specific MicroRNA-124a Alters the Inflammatory Response in the Formalin Test in Mice
  Pain. Mar, 2013  |   Pubmed ID: 23318130
• Phenotyping the Function of TRPV1-expressing Sensory Neurons by Targeted Axonal Silencing
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2013  |   Pubmed ID: 23283344
• NOXious Signaling in Pain Processing
  Pharmacology & Therapeutics. Mar, 2013  |   Pubmed ID: 23146925
• Pharmacokinetics of Non-intravenous Formulations of Fentanyl
  Clinical Pharmacokinetics. Jan, 2013  |   Pubmed ID: 23100195
• Inhibition of GTP Cyclohydrolase Attenuates Tumor Growth by Reducing Angiogenesis and M2-like Polarization of Tumor Associated Macrophages
  International Journal of Cancer. Feb, 2013  |   Pubmed ID: 22753274
• Intrinsic Up-regulation of 2-AG Favors an Area Specific Neuronal Survival in Different in Vitro Models of Neuronal Damage
  PloS One. 2012  |   Pubmed ID: 23284665
• Necessity and Risks of Arterial Blood Sampling in Healthy Volunteer Studies
  Clinical Pharmacokinetics. Oct, 2012  |   Pubmed ID: 23018527
• NADPH Oxidase-4 Maintains Neuropathic Pain After Peripheral Nerve Injury
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2012  |   Pubmed ID: 22836249
• The P21-activated Kinase PAK 5 is Involved in Formalin-induced Nociception Through Regulation of MAP-kinase Signaling and Formalin-specific Receptors
  Behavioural Brain Research. Sep, 2012  |   Pubmed ID: 22732262
• Analysis of Sphingolipid and Prostaglandin Synthesis During Zymosan-induced Inflammation
  Prostaglandins & Other Lipid Mediators. Oct, 2012  |   Pubmed ID: 22732087
• Lack of Microsomal Prostaglandin E(2) Synthase-1 in Bone Marrow-derived Myeloid Cells Impairs Left Ventricular Function and Increases Mortality After Acute Myocardial Infarction
  Circulation. Jun, 2012  |   Pubmed ID: 22589381
• Inhibitor Kappa B Kinase Beta Dependent Cytokine Upregulation in Nociceptive Neurons Contributes to Nociceptive Hypersensitivity After Sciatic Nerve Injury
  The Journal of Pain : Official Journal of the American Pain Society. May, 2012  |   Pubmed ID: 22564672
• 5,6-EET is Released Upon Neuronal Activity and Induces Mechanical Pain Hypersensitivity Via TRPA1 on Central Afferent Terminals
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2012  |   Pubmed ID: 22553041
• Ceramide Synthase 6 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2012  |   Pubmed ID: 22544924
• Site-specific and Time-dependent Activation of the Endocannabinoid System After Transection of Long-range Projections
  PloS One. 2012  |   Pubmed ID: 22457773
• Structure-activity Relationship of Nonacidic Quinazolinone Inhibitors of Human Microsomal Prostaglandin Synthase 1 (mPGES 1)
  Journal of Medicinal Chemistry. Apr, 2012  |   Pubmed ID: 22449023
• The Pharmacogenetic Background of Hepatitis C Treatment
  Mutation Research. Mar, 2012  |   Pubmed ID: 22409946
• Sniffing out Pharmacology: Interactions of Drugs with Human Olfaction
  Trends in Pharmacological Sciences. Apr, 2012  |   Pubmed ID: 22361590
• Identification of DNA-protein Complexes Using an Improved, Combined Western Blotting-electrophoretic Mobility Shift Assay (WEMSA) with a Fluorescence Imaging System
  Molecular BioSystems. Apr, 2012  |   Pubmed ID: 22358373
• Long Chain Ceramides and Very Long Chain Ceramides Have Opposite Effects on Human Breast and Colon Cancer Cell Growth
  The International Journal of Biochemistry & Cell Biology. Apr, 2012  |   Pubmed ID: 22230369
• Chain Length-specific Properties of Ceramides
  Progress in Lipid Research. Jan, 2012  |   Pubmed ID: 22133871
• Dimethylcelecoxib Induces an Inhibitory Complex Consisting of HDAC1/NF-κB(p65)RelA Leading to Transcriptional Downregulation of MPGES-1 and EGR1
  Cellular Signalling. Feb, 2012  |   Pubmed ID: 21983014
• Inhibitors of Specific Ceramide Synthases
  Biochimie. Feb, 2012  |   Pubmed ID: 21945810
• Prolonged Zymosan-induced Inflammatory Pain Hypersensitivity in Mice Lacking Glycine Receptor Alpha2
  Behavioural Brain Research. Jan, 2012  |   Pubmed ID: 21924294
• Additive Antinociceptive Effects of a Combination of Vitamin C and Vitamin E After Peripheral Nerve Injury
  PloS One. 2011  |   Pubmed ID: 22195029
• Single and Combined IL28B, ITPA and SLC28A3 Host Genetic Markers Modulating Response to Anti-hepatitis C Therapy
  Pharmacogenomics. Dec, 2011  |   Pubmed ID: 22118055
• Low-dose Drug Combinations Along Molecular Pathways Could Maximize Therapeutic Effectiveness While Minimizing Collateral Adverse Effects
  Drug Discovery Today. Dec, 2011  |   Pubmed ID: 22016087
• Soluble Epoxide Hydrolase Limits Mechanical Hyperalgesia During Inflammation
  Molecular Pain. 2011  |   Pubmed ID: 21970373
• Group V Phospholipase A2 in Bone Marrow-derived Myeloid Cells and Bronchial Epithelial Cells Promotes Bacterial Clearance After Escherichia Coli Pneumonia
  The Journal of Biological Chemistry. Oct, 2011  |   Pubmed ID: 21849511
• The Protein Kinase IKKε is a Potential Target for the Treatment of Inflammatory Hyperalgesia
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2011  |   Pubmed ID: 21813779
• CNGA3: a Target of Spinal Nitric Oxide/cGMP Signaling and Modulator of Inflammatory Pain Hypersensitivity
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2011  |   Pubmed ID: 21813679
• Nerve Injury Evoked Loss of Latexin Expression in Spinal Cord Neurons Contributes to the Development of Neuropathic Pain
  PloS One. 2011  |   Pubmed ID: 21572518
• Macrophages Programmed by Apoptotic Cells Promote Angiogenesis Via Prostaglandin E2
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2011  |   Pubmed ID: 21450910
• SNO-ing at the Nociceptive Synapse?
  Pharmacological Reviews. Jun, 2011  |   Pubmed ID: 21436345
• MicroRNAs As New Players in the Pain Game
  Pain. Jul, 2011  |   Pubmed ID: 21353390
• Role of Nucleoside Transporters SLC28A2/3 and SLC29A1/2 Genetics in Ribavirin Therapy: Protection Against Anemia in Patients with Chronic Hepatitis C
  Pharmacogenetics and Genomics. May, 2011  |   Pubmed ID: 21346688
• The Ubiquitin Ligase MYCBP2 Regulates Transient Receptor Potential Vanilloid Receptor 1 (TRPV1) Internalization Through Inhibition of P38 MAPK Signaling
  The Journal of Biological Chemistry. Feb, 2011  |   Pubmed ID: 21098484
• Anti-inflammatory Role of Microsomal Prostaglandin E Synthase-1 in a Model of Neuroinflammation
  The Journal of Biological Chemistry. Jan, 2011  |   Pubmed ID: 21075851
• Pharmacogenetics of New Analgesics
  British Journal of Pharmacology. Jun, 2011  |   Pubmed ID: 20942817
• Epigenetics in Pain and Analgesia: an Imminent Research Field
  European Journal of Pain (London, England). Jan, 2011  |   Pubmed ID: 20584621
• Screening for IL28B Gene Variants Identifies Predictors of Hepatitis C Therapy Success
  Antiviral Therapy. 2010  |   Pubmed ID: 21149916
• Localization of an Endocannabinoid System in the Hypophysial Pars Tuberalis and Pars Distalis of Man
  Cell and Tissue Research. Nov, 2010  |   Pubmed ID: 20957495
• Activation of Ceramide Synthase 6 by Celecoxib Leads to a Selective Induction of C16:0-ceramide
  Biochemical Pharmacology. Dec, 2010  |   Pubmed ID: 20735991
• Inhibition of the Soluble Epoxide Hydrolase Promotes Albuminuria in Mice with Progressive Renal Disease
  PloS One. 2010  |   Pubmed ID: 20694143
• Dimethylcelecoxib Inhibits MPGES-1 Promoter Activity by Influencing EGR1 and NF-κB
  Biochemical Pharmacology. Nov, 2010  |   Pubmed ID: 20688046
• R-flurbiprofen Reduces Neuropathic Pain in Rodents by Restoring Endogenous Cannabinoids
  PloS One. 2010  |   Pubmed ID: 20498712
• Higher Pain Scores, Similar Opioid Doses and Side Effects Associated with Antipyretic Analgesics in Specialised Tertiary Pain Care
  Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]. Nov, 2010  |   Pubmed ID: 20490889
• A Critical Appraisal of Human Genotyping for Pain Therapy
  Trends in Pharmacological Sciences. Jul, 2010  |   Pubmed ID: 20483491
• Alterations in the Hippocampal Endocannabinoid System in Diet-induced Obese Mice
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2010  |   Pubmed ID: 20445053
• Ziconotide for Treatment of Severe Chronic Pain
  Lancet (London, England). May, 2010  |   Pubmed ID: 20413151
• Analysis of NF-kappaB Signaling Pathways by Proteomic Approaches
  Expert Review of Proteomics. Apr, 2010  |   Pubmed ID: 20377387
• Soluble Epoxide Hydrolase Deficiency Attenuates Neointima Formation in the Femoral Cuff Model of Hyperlipidemic Mice
  Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2010  |   Pubmed ID: 20224052
• Cleavage of Sphingosine Kinase 2 by Caspase-1 Provokes Its Release from Apoptotic Cells
  Blood. Apr, 2010  |   Pubmed ID: 20197547
• An Endocannabinoid System is Localized to the Hypophysial Pars Tuberalis of Syrian Hamsters and Responds to Photoperiodic Changes
  Cell and Tissue Research. Apr, 2010  |   Pubmed ID: 20165884
• Sulindac Sulfide Suppresses 5-lipoxygenase at Clinically Relevant Concentrations
  Cellular and Molecular Life Sciences : CMLS. Mar, 2010  |   Pubmed ID: 20091083
• Nonacidic Inhibitors of Human Microsomal Prostaglandin Synthase 1 (mPGES 1) Identified by a Multistep Virtual Screening Protocol
  Journal of Medicinal Chemistry. Jan, 2010  |   Pubmed ID: 20025212
• Highly Sensitive Determination of HCV Protease Inhibitors Boceprevir (SCH 503034) and Telaprevir (VX 950) in Human Plasma by LC-MS/MS
  Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Dec, 2009  |   Pubmed ID: 19864192
• Cross-sectional Assessment of the Consequences of a GTP Cyclohydrolase 1 Haplotype for Specialized Tertiary Outpatient Pain Care
  The Clinical Journal of Pain. Nov-Dec, 2009  |   Pubmed ID: 19851158
• Inhibitor KappaB Kinase Beta Deficiency in Primary Nociceptive Neurons Increases TRP Channel Sensitivity
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2009  |   Pubmed ID: 19828806
• Analgesic Efficacy of Tramadol, Pregabalin and Ibuprofen in Menthol-evoked Cold Hyperalgesia
  Pain. Dec, 2009  |   Pubmed ID: 19762153
• Toponomics Analysis of Drug-induced Changes in Arachidonic Acid-dependent Signaling Pathways During Spinal Nociceptive Processing
  Journal of Proteome Research. Oct, 2009  |   Pubmed ID: 19697962
• Identification of Human Cathepsin G As a Functional Target of Boswellic Acids from the Anti-inflammatory Remedy Frankincense
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2009  |   Pubmed ID: 19648270
• Cellular Membranes Function As a Storage Compartment for Celecoxib
  Journal of Molecular Medicine (Berlin, Germany). Oct, 2009  |   Pubmed ID: 19641861
• Sphingosine Kinase 2 Deficient Tumor Xenografts Show Impaired Growth and Fail to Polarize Macrophages Towards an Anti-inflammatory Phenotype
  International Journal of Cancer. Nov, 2009  |   Pubmed ID: 19618460
• Genetic Modulation of the Pharmacological Treatment of Pain
  Pharmacology & Therapeutics. Nov, 2009  |   Pubmed ID: 19615406
• Cross-sectional Analysis of the Influence of Currently Known Pharmacogenetic Modulators on Opioid Therapy in Outpatient Pain Centers
  Pharmacogenetics and Genomics. Jun, 2009  |   Pubmed ID: 19514130
• No NO, No Pain? The Role of Nitric Oxide and CGMP in Spinal Pain Processing
  Trends in Neurosciences. Jun, 2009  |   Pubmed ID: 19414201
• Can Extremely Low or High Morphine Formation from Codeine Be Predicted Prior to Therapy Initiation?
  Pain. Jul, 2009  |   Pubmed ID: 19395173
• Genetic Variants Altering Dopamine D2 Receptor Expression or Function Modulate the Risk of Opiate Addiction and the Dosage Requirements of Methadone Substitution
  Pharmacogenetics and Genomics. Jun, 2009  |   Pubmed ID: 19373123
• Capturing Adenylyl Cyclases As Potential Drug Targets
  Nature Reviews. Drug Discovery. Apr, 2009  |   Pubmed ID: 19337273
• Ceramide Synthases and Ceramide Levels Are Increased in Breast Cancer Tissue
  Carcinogenesis. May, 2009  |   Pubmed ID: 19279183
• Prostaglandin D(2) Sustains the Pyrogenic Effect of Prostaglandin E(2)
  European Journal of Pharmacology. Apr, 2009  |   Pubmed ID: 19249295
• Inhibition of the Soluble Epoxide Hydrolase Attenuates Monocrotaline-induced Pulmonary Hypertension in Rats
  Journal of Hypertension. Feb, 2009  |   Pubmed ID: 19226702
• Multidrug Resistance-related Protein 2 Genotype of the Donor Affects Kidney Graft Function
  Pharmacogenetics and Genomics. Apr, 2009  |   Pubmed ID: 19214140
• The S1P(2) Receptor Expressed in Human Platelets is Linked to the RhoA-Rho Kinase Pathway and is Down Regulated in Type 2 Diabetes
  Basic Research in Cardiology. May, 2009  |   Pubmed ID: 19139947
• A Common Human Micro-opioid Receptor Genetic Variant Diminishes the Receptor Signaling Efficacy in Brain Regions Processing the Sensory Information of Pain
  The Journal of Biological Chemistry. Mar, 2009  |   Pubmed ID: 19116204
• Comparison of Nociceptive Behavior in Prostaglandin E, F, D, Prostacyclin and Thromboxane Receptor Knockout Mice
  European Journal of Pain (London, England). Aug, 2009  |   Pubmed ID: 18938093
• The Selective COX-2 Inhibitor Celecoxib Modulates Sphingolipid Synthesis
  Journal of Lipid Research. Jan, 2009  |   Pubmed ID: 18711209
• Update on the Pathobiology of Neuropathic Pain
  Expert Review of Proteomics. Dec, 2008  |   Pubmed ID: 19086860
• Sphingosine 1-phosphate Modulates Spinal Nociceptive Processing
  The Journal of Biological Chemistry. Nov, 2008  |   Pubmed ID: 18805787
• Toponomics Analysis of Functional Interactions of the Ubiquitin Ligase PAM (Protein Associated with Myc) During Spinal Nociceptive Processing
  Molecular & Cellular Proteomics : MCP. Dec, 2008  |   Pubmed ID: 18753128
• CGMP Produced by NO-sensitive Guanylyl Cyclase Essentially Contributes to Inflammatory and Neuropathic Pain by Using Targets Different from CGMP-dependent Protein Kinase I
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2008  |   Pubmed ID: 18716216
• Genetic Deletion of Synapsin II Reduces Neuropathic Pain Due to Reduced Glutamate but Increased GABA in the Spinal Cord Dorsal Horn
  Pain. Oct, 2008  |   Pubmed ID: 18701217
• Celecoxib Inhibits 5-lipoxygenase
  Biochemical Pharmacology. Oct, 2008  |   Pubmed ID: 18692027
• Keratinocyte-derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-activated Receptor-gamma Agonist Troglitazone but Not Rosiglitazone and Involves Activation of P38 Mitogen-activated Protein Kinase: Implications for Diabetes-impaired Skin Repair
  Molecular Pharmacology. Oct, 2008  |   Pubmed ID: 18599600
• The IKK-NF-kappaB Pathway: a Source for Novel Molecular Drug Targets in Pain Therapy?
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2008  |   Pubmed ID: 18559989
• The Anti-proliferative Potency of Celecoxib is Not a Class Effect of Coxibs
  Biochemical Pharmacology. Jul, 2008  |   Pubmed ID: 18547544
• Dimethylcelecoxib Inhibits Prostaglandin E2 Production
  Biochemical Pharmacology. Jul, 2008  |   Pubmed ID: 18508034
• Antinociceptive Activity of the S1P-receptor Agonist FTY720
  Journal of Cellular and Molecular Medicine. Jun, 2008  |   Pubmed ID: 18494940
• Genetic Polymorphism of the Type A Human Natriuretic Peptide Receptor (NPR-A) Gene Contributes to the Interindividual Variability in the BNP System
  European Journal of Heart Failure. May, 2008  |   Pubmed ID: 18436476
• Consequences of Altered Eicosanoid Patterns for Nociceptive Processing in MPGES-1-deficient Mice
  Journal of Cellular and Molecular Medicine. Apr, 2008  |   Pubmed ID: 18419601
• Biphasic Regulation of HMG-CoA Reductase Expression and Activity During Wound Healing and Its Functional Role in the Control of Keratinocyte Angiogenic and Proliferative Responses
  The Journal of Biological Chemistry. May, 2008  |   Pubmed ID: 18390541
• Reduced Hyperalgesia in Homozygous Carriers of a GTP Cyclohydrolase 1 Haplotype
  European Journal of Pain (London, England). Nov, 2008  |   Pubmed ID: 18374612
• Microsomal Prostaglandin E2 Synthase-1 Deletion Leads to Adverse Left Ventricular Remodeling After Myocardial Infarction
  Circulation. Apr, 2008  |   Pubmed ID: 18347209
• Cysteine-rich Protein 2, a Novel Downstream Effector of CGMP/cGMP-dependent Protein Kinase I-mediated Persistent Inflammatory Pain
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2008  |   Pubmed ID: 18256252
• Proteomics in Neuropathic Pain Research
  Anesthesiology. Feb, 2008  |   Pubmed ID: 18212577
• Microarray Analysis of Altered Sphingolipid Metabolism Reveals Prognostic Significance of Sphingosine Kinase 1 in Breast Cancer
  Breast Cancer Research and Treatment. Nov, 2008  |   Pubmed ID: 18058224
• P53 is Important for the Anti-proliferative Effect of Ibuprofen in Colon Carcinoma Cells
  Biochemical and Biophysical Research Communications. Jan, 2008  |   Pubmed ID: 18036557
• Pyrosequencing of Polymorphisms in the COX-2 Gene (PTGS2) with Reported Clinical Relevance
  Pharmacogenomics. Dec, 2007  |   Pubmed ID: 18085997
• Rapid Screening for Potentially Relevant Polymorphisms in the Human Fatty Acid Amide Hydrolase Gene Using Pyrosequencing
  Prostaglandins & Other Lipid Mediators. Nov, 2007  |   Pubmed ID: 17991615
• Current Evidence for a Modulation of Nociception by Human Genetic Polymorphisms
  Pain. Nov, 2007  |   Pubmed ID: 17706868
• The Impact of CREB and Its Phosphorylation at Ser142 on Inflammatory Nociception
  Biochemical and Biophysical Research Communications. Oct, 2007  |   Pubmed ID: 17692820
• Tumor Cell Apoptosis Polarizes Macrophages Role of Sphingosine-1-phosphate
  Molecular Biology of the Cell. Oct, 2007  |   Pubmed ID: 17652460
• Effects of Parecoxib and Dipyrone on Platelet Aggregation in Patients Undergoing Meniscectomy: a Double-blind, Randomized, Parallel-group Study
  Clinical Therapeutics. Mar, 2007  |   Pubmed ID: 17577465
• Association of Saquinavir Plasma Concentrations with Side Effects but Not with Antiretroviral Outcome in Patients Infected with Protease Inhibitor-susceptible Human Immunodeficiency Virus Type 1
  Antimicrobial Agents and Chemotherapy. Sep, 2007  |   Pubmed ID: 17576836
• FTY720 Ameliorates Oxazolone Colitis in Mice by Directly Affecting T Helper Type 2 Functions
  Molecular Immunology. Jul, 2007  |   Pubmed ID: 17475330
• PGD2 Metabolism in Plasma: Kinetics and Relationship with Bioactivity on DP1 and CRTH2 Receptors
  Biochemical Pharmacology. Jun, 2007  |   Pubmed ID: 17452035
• Reliable Screening for a Pain-protective Haplotype in the GTP Cyclohydrolase 1 Gene (GCH1) Through the Use of 3 or Fewer Single Nucleotide Polymorphisms
  Clinical Chemistry. Jun, 2007  |   Pubmed ID: 17363416
• The Effects of COX-2 Selective and Non-selective NSAIDs on the Initiation and Progression of Atherosclerosis in ApoE-/- Mice
  Journal of Molecular Medicine (Berlin, Germany). Jun, 2007  |   Pubmed ID: 17318614
• FTY720 Ameliorates Th1-mediated Colitis in Mice by Directly Affecting the Functional Activity of CD4+CD25+ Regulatory T Cells
  Journal of Immunology (Baltimore, Md. : 1950). Feb, 2007  |   Pubmed ID: 17277153
• Impaired Acute and Inflammatory Nociception in Mice Lacking the P50 Subunit of NF-kappaB
  European Journal of Pharmacology. Mar, 2007  |   Pubmed ID: 17217946
• Pharmacological and Histopathological Characterization of a Hyperalgesia Model Induced by Freeze Lesion
  Pain. Feb, 2007  |   Pubmed ID: 17189672
• The Cyclooxygenase 2 Genetic Variant -765G>C Does Not Modulate the Effects of Celecoxib on Prostaglandin E2 Production
  Clinical Pharmacology and Therapeutics. Dec, 2006  |   Pubmed ID: 17178263
• LC-MS/MS-analysis of Sphingosine-1-phosphate and Related Compounds in Plasma Samples
  Prostaglandins & Other Lipid Mediators. Dec, 2006  |   Pubmed ID: 17085324
• GTP Cyclohydrolase and Tetrahydrobiopterin Regulate Pain Sensitivity and Persistence
  Nature Medicine. Nov, 2006  |   Pubmed ID: 17057711
• Pyrosequencing-based Screening for Genetic Polymorphisms in Cytochrome P450 2B6 of Potential Clinical Relevance
  Pharmacogenomics. Oct, 2006  |   Pubmed ID: 17054410
• Fatal Respiratory Depression After Multiple Intravenous Morphine Injections
  Clinical Pharmacokinetics. 2006  |   Pubmed ID: 17048971
• The Mu-opioid Receptor Gene Polymorphism 118A>G Depletes Alfentanil-induced Analgesia and Protects Against Respiratory Depression in Homozygous Carriers
  Pharmacogenetics and Genomics. Sep, 2006  |   Pubmed ID: 16906017
• Nimodipine Plasma Concentration and Retinal Blood Flow in Healthy Subjects
  Investigative Ophthalmology & Visual Science. Aug, 2006  |   Pubmed ID: 16877419
• Inhibition of Prostaglandin E2 Synthesis by SC-560 is Independent of Cyclooxygenase 1 Inhibition
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2006  |   Pubmed ID: 16816110
• Is MPGES-1 a Promising Target for Pain Therapy?
  Trends in Pharmacological Sciences. Aug, 2006  |   Pubmed ID: 16815559
• Misestimating the Role of an Active Metabolite when Modeling the Effects After Administration of the Parent Compound Only
  Clinical Pharmacology and Therapeutics. Jul, 2006  |   Pubmed ID: 16815321
• The Glutamate Transporter GLAST is Involved in Spinal Nociceptive Processing
  Biochemical and Biophysical Research Communications. Jul, 2006  |   Pubmed ID: 16765320
• Cyclooxygenase-2 (COX-2)-independent Anticarcinogenic Effects of Selective COX-2 Inhibitors
  Journal of the National Cancer Institute. Jun, 2006  |   Pubmed ID: 16757698
• Evidence of COX-2 Independent Induction of Apoptosis and Cell Cycle Block in Human Colon Carcinoma Cells After S- or R-ibuprofen Treatment
  European Journal of Pharmacology. Jul, 2006  |   Pubmed ID: 16730702
• Apoptotic Cells Promote Macrophage Survival by Releasing the Antiapoptotic Mediator Sphingosine-1-phosphate
  Blood. Sep, 2006  |   Pubmed ID: 16690965
• High Sensitive Determination of Sufentanil in Human Plasma of Parturients and Neonates Following Patient-controlled Epidural Analgesia (PCEA)
  Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. May, 2006  |   Pubmed ID: 16621739
• Different COX-independent Effects of the COX-2 Inhibitors Etoricoxib and Lumiracoxib
  Biochemical and Biophysical Research Communications. Apr, 2006  |   Pubmed ID: 16598848
• Cardiovascular Risk with Cyclooxygenase Inhibitors: General Problem with Substance Specific Differences?
  Naunyn-Schmiedeberg's Archives of Pharmacology. Apr, 2006  |   Pubmed ID: 16586083
• Rapid Identification of Three Functionally Relevant Polymorphisms in the OATP1B1 Transporter Gene Using Pyrosequencing
  Pharmacogenomics. Mar, 2006  |   Pubmed ID: 16515396
• Current Evidence for a Genetic Modulation of the Response to Analgesics
  Pain. Mar, 2006  |   Pubmed ID: 16472919
• Modulation of the Central Nervous Effects of Levomethadone by Genetic Polymorphisms Potentially Affecting Its Metabolism, Distribution, and Drug Action
  Clinical Pharmacology and Therapeutics. Jan, 2006  |   Pubmed ID: 16413243