Janet L. Smith Bioscience Division Millipore Inc Biography Publications Institution JoVE Articles Janet L. Smith has not added a biography. If you are Janet L. Smith and would like to personalize this page please email our Author Liaison for assistance. Publications Targeting Phosphoinositide 3-kinase δ for Allergic Asthma Biochemical Society Transactions. Feb, 2012 | Pubmed ID: 22260698 Structure and Activity of DmmA, a Marine Haloalkane Dehalogenase Protein Science : a Publication of the Protein Society. Feb, 2012 | Pubmed ID: 22124946 A New Generation of Crystallographic Validation Tools for the Protein Data Bank Structure (London, England : 1993). Oct, 2011 | Pubmed ID: 22000512 A New Structural Form in the SAM/metal-dependent O‑methyltransferase Family: MycE from the Mycinamicin Biosynthetic Pathway Journal of Molecular Biology. Oct, 2011 | Pubmed ID: 21884704 Automated Sample-scanning Methods for Radiation Damage Mitigation and Diffraction-based Centering of Macromolecular Crystals Journal of Synchrotron Radiation. Sep, 2011 | Pubmed ID: 21862850 A Resource for Discovering Specific and Universal Biomarkers for Distributed Stem Cells PloS One. 2011 | Pubmed ID: 21818293 Fast Fluorescence Techniques for Crystallography Beamlines Journal of Applied Crystallography. Aug, 2011 | Pubmed ID: 21808424 Structural Basis of Multifunctionality in a Vitamin B12-processing Enzyme The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21697092 Heterologous Production, Purification and Characterization of Enzymatically Active Sindbis Virus Nonstructural Protein NsP1 Protein Expression and Purification. Oct, 2011 | Pubmed ID: 21693190 Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces Coelicolor The Journal of Biological Chemistry. Jun, 2011 | Pubmed ID: 21543318 Radiation Damage in Protein Crystals is Reduced with a Micron-sized X-ray Beam Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21444772 JBluIce-EPICS Control System for Macromolecular Crystallography Acta Crystallographica. Section D, Biological Crystallography. Mar, 2011 | Pubmed ID: 21358048 Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis: Structure of a Decarboxylating Thioesterase The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21357626 New Ligation-independent Cloning Vectors Compatible with a High-throughput Platform for Parallel Construct Expression Evaluation Using Baculovirus-infected Insect Cells Protein Expression and Purification. May, 2011 | Pubmed ID: 21262364 Structural Basis for Substrate Activation and Regulation by Cystathionine Beta-synthase (CBS) Domains in Cystathionine {beta}-synthase Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010 | Pubmed ID: 21081698 A General Scheme for Synthesis of Substrate-based Polyketide Labels for Acyl Carrier Proteins Bioorganic & Medicinal Chemistry Letters. Oct, 2010 | Pubmed ID: 20801036 Conformational Switch Triggered by Alpha-ketoglutarate in a Halogenase of Curacin A Biosynthesis Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20660778 Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide Hydrolase Angewandte Chemie (International Ed. in English). Aug, 2010 | Pubmed ID: 20623733 Structure of the Rift Valley Fever Virus Nucleocapsid Protein Reveals Another Architecture for RNA Encapsidation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20547879 Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway Structure (London, England : 1993). Jan, 2010 | Pubmed ID: 20152156 Insights into the Reactivation of Cobalamin-dependent Methionine Synthase Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19846791 Polyketide Decarboxylative Chain Termination Preceded by O-sulfonation in Curacin a Biosynthesis Journal of the American Chemical Society. Nov, 2009 | Pubmed ID: 19835378 Identification of Inhibitors of Yellow Fever Virus Replication Using a Replicon-based High-throughput Assay Antimicrobial Agents and Chemotherapy. Oct, 2009 | Pubmed ID: 19651907 Insights into TRNA-dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex Aeolicus Enzyme Journal of Molecular Biology. Aug, 2009 | Pubmed ID: 19520089 Metamorphic Enzyme Assembly in Polyketide Diversification Nature. Jun, 2009 | Pubmed ID: 19494914 Mini-beam Collimator Enables Microcrystallography Experiments on Standard Beamlines Journal of Synchrotron Radiation. Mar, 2009 | Pubmed ID: 19240333 Structural Basis for Binding Specificity Between Subclasses of Modular Polyketide Synthase Docking Domains ACS Chemical Biology. Jan, 2009 | Pubmed ID: 19146481 Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic Pathway The Journal of Biological Chemistry. Feb, 2009 | Pubmed ID: 19103602 Characterization of Purified Sindbis Virus NsP4 RNA-dependent RNA Polymerase Activity in Vitro Virology. Feb, 2009 | Pubmed ID: 19036396 Mocr: a Novel Fusion Tag for Enhancing Solubility That is Compatible with Structural Biology Applications Protein Expression and Purification. Jan, 2009 | Pubmed ID: 18824232 Proteins: Ever Larger, Stranger and More Dynamic Current Opinion in Structural Biology. Dec, 2008 | Pubmed ID: 19041238 Biochemistry. An Enzyme Assembly Line Science (New York, N.Y.). Sep, 2008 | Pubmed ID: 18772425 Role for Conserved Residues of Sindbis Virus Nonstructural Protein 2 Methyltransferase-like Domain in Regulation of Minus-strand Synthesis and Development of Cytopathic Infection Journal of Virology. Aug, 2008 | Pubmed ID: 18495773 A 7μm Mini-beam Improves Diffraction Data from Small or Imperfect Crystals of Macromolecules Acta Crystallographica. Section D, Biological Crystallography. Apr, 2008 | Pubmed ID: 18391409 Metal Active Site Elasticity Linked to Activation of Homocysteine in Methionine Synthases Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18296644 Pyr RNA Binding to the Bacillus Caldolyticus PyrR Attenuation Protein - Characterization and Regulation by Uridine and Guanosine Nucleotides The FEBS Journal. Feb, 2008 | Pubmed ID: 18190533 GNAT-like Strategy for Polyketide Chain Initiation Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 17991863 Crystal Structure of the ECH2 Catalytic Domain of CurF from Lyngbya Majuscula. Insights into a Decarboxylase Involved in Polyketide Chain Beta-branching The Journal of Biological Chemistry. Dec, 2007 | Pubmed ID: 17928301 Functional Characterization of Cis and Trans Activity of the Flavivirus NS2B-NS3 Protease The Journal of Biological Chemistry. Apr, 2007 | Pubmed ID: 17337448 Clearing the Skies over Modular Polyketide Synthases ACS Chemical Biology. Sep, 2006 | Pubmed ID: 17168537 Catalytic Core of Alphavirus Nonstructural Protein NsP4 Possesses Terminal Adenylyltransferase Activity Journal of Virology. Oct, 2006 | Pubmed ID: 17005674 Structural and Mechanistic Insights into Polyketide Macrolactonization from Polyketide-based Affinity Labels Nature Chemical Biology. Oct, 2006 | Pubmed ID: 16969373 Structural Basis for Macrolactonization by the Pikromycin Thioesterase Nature Chemical Biology. Oct, 2006 | Pubmed ID: 16969372 At a Crossroad: Standing Still and Moving Forward American Journal of Community Psychology. Sep, 2006 | Pubmed ID: 16832607 Transmembrane Traffic in the Cytochrome B6f Complex Annual Review of Biochemistry. 2006 | Pubmed ID: 16756511 The Dictyostelium Kinome--analysis of the Protein Kinases from a Simple Model Organism PLoS Genetics. Mar, 2006 | Pubmed ID: 16596165 Myosin Light Chain Kinase A is Activated by CGMP-dependent and CGMP-independent Pathways FEBS Letters. Apr, 2006 | Pubmed ID: 16546177 Structure of the Flavivirus Helicase: Implications for Catalytic Activity, Protein Interactions, and Proteolytic Processing Journal of Virology. Aug, 2005 | Pubmed ID: 16051820 The Apo and Ternary Complex Structures of a Chemotherapeutic Target: Human Glycinamide Ribonucleotide Transformylase Biochemistry. Jul, 2005 | Pubmed ID: 16026156 Structure of the Cytochrome B6f Complex: New Prosthetic Groups, Q-space, and the 'hors D'oeuvres Hypothesis' for Assembly of the Complex Photosynthesis Research. 2005 | Pubmed ID: 15977064 Identification of Potent and Selective RNA Antagonists of the IFN-gamma-inducible CXCL10 Chemokine Biochemistry. Jun, 2005 | Pubmed ID: 15938634 A New Arrangement of (beta/alpha)8 Barrels in the Synthase Subunit of PLP Synthase The Journal of Biological Chemistry. Jul, 2005 | Pubmed ID: 15911615 Structure of the Nucleotide Complex of PyrR, the Pyr Attenuation Protein from Bacillus Caldolyticus, Suggests Dual Regulation by Pyrimidine and Purine Nucleotides Journal of Bacteriology. Mar, 2005 | Pubmed ID: 15716449 Design, Expression, and Purification of a Flaviviridae Polymerase Using a High-throughput Approach to Facilitate Crystal Structure Determination Protein Science : a Publication of the Protein Society. Oct, 2004 | Pubmed ID: 15388860 Cytochrome Bc Complexes: a Common Core of Structure and Function Surrounded by Diversity in the Outlying Provinces Current Opinion in Structural Biology. Aug, 2004 | Pubmed ID: 15313237 [Structure and Function of the Cytochrome B6f Complex of Oxygenic Photosynthesis] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Jul, 2004 | Pubmed ID: 15242052 Evolution of Photosynthesis: Time-independent Structure of the Cytochrome B6f Complex Biochemistry. May, 2004 | Pubmed ID: 15147175 The Structure of the RNA-dependent RNA Polymerase from Bovine Viral Diarrhea Virus Establishes the Role of GTP in De Novo Initiation Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 15070734 Crystal Structure of Imidazole Glycerol-phosphate Dehydratase: Duplication of an Unusual Fold The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14724278 Regulatory Mechanism of Dictyostelium Myosin Light Chain Kinase A The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14570871 Structure of the Cytochrome B6f Complex of Oxygenic Photosynthesis: Tuning the Cavity Science (New York, N.Y.). Nov, 2003 | Pubmed ID: 14526088 Functional Dissection of the Bacillus Subtilis Pur Operator Site Journal of Bacteriology. Jul, 2003 | Pubmed ID: 12837784 The Purine Repressor of Bacillus Subtilis: a Novel Combination of Domains Adapted for Transcription Regulation Journal of Bacteriology. Jul, 2003 | Pubmed ID: 12837783 Substrate-induced Changes in the Ammonia Channel for Imidazole Glycerol Phosphate Synthase Biochemistry. Jun, 2003 | Pubmed ID: 12795596 Toward Understanding the Mechanism of the Complex Cyclization Reaction Catalyzed by Imidazole Glycerolphosphate Synthase: Crystal Structures of a Ternary Complex and the Free Enzyme Biochemistry. Jun, 2003 | Pubmed ID: 12795595 A Defined Protein-detergent-lipid Complex for Crystallization of Integral Membrane Proteins: The Cytochrome B6f Complex of Oxygenic Photosynthesis Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12702760 CGMP Signalling: Different Ways to Create a Pathway Trends in Genetics : TIG. Mar, 2003 | Pubmed ID: 12615006 Differential Functional Properties of Calmodulin-dependent Protein Kinase IIgamma Variants Isolated from Smooth Muscle The Biochemical Journal. Jun, 2003 | Pubmed ID: 12603201 Signaling Pathways Regulating Dictyostelium Myosin II Journal of Muscle Research and Cell Motility. 2002 | Pubmed ID: 12952069 Dictyostelium Discoideum Has a Single Diacylglycerol Kinase Gene with Similarity to Mammalian Theta Isoforms The Biochemical Journal. Dec, 2002 | Pubmed ID: 12296770 A Novel CGMP Signalling Pathway Mediating Myosin Phosphorylation and Chemotaxis in Dictyostelium The EMBO Journal. Sep, 2002 | Pubmed ID: 12198158 Identification of Four Candidate CGMP Targets in Dictyostelium Proceedings of the National Academy of Sciences of the United States of America. May, 2002 | Pubmed ID: 12011437 A Biologist's Guide to Synchrotron Facilities: the BioSync Web Resource Trends in Biochemical Sciences. Apr, 2002 | Pubmed ID: 11943550 Het bepalen van het aantal cellen tijdens de celdeling Cultuur met de Scepter Cell Counter Kathleen Ongena1, Chandreyee Das1, Janet L. Smith1, Sónia Gil1, Grace Johnston1 1Bioscience Division, Millipore Inc JoVE 2204 Biologie
Het bepalen van het aantal cellen tijdens de celdeling Cultuur met de Scepter Cell Counter Kathleen Ongena1, Chandreyee Das1, Janet L. Smith1, Sónia Gil1, Grace Johnston1 1Bioscience Division, Millipore Inc JoVE 2204 Biologie