Jie Zhou

Publications

• A Pan-sarbecovirus Vaccine Induces Highly Potent and Durable Neutralizing Antibody Responses in Non-human Primates Against SARS-CoV-2 Omicron Variant
  Cell Research. Feb, 2022  |   Pubmed ID: 35210607
• Discovery of a Novel Megakaryopoiesis Enhancer, Ingenol, Promoting Thrombopoiesis Through PI3K-Akt Signaling Independent of Thrombopoietin
  Pharmacological Research. Mar, 2022  |   Pubmed ID: 35077844
• Attenuated Replication and Pathogenicity of SARS-CoV-2 B.1.1.529 Omicron
  Nature. Jan, 2022  |   Pubmed ID: 35062016
• SPINK6 Inhibits Human Airway Serine Proteases and Restricts Influenza Virus Activation
  EMBO Molecular Medicine. 01, 2022  |   Pubmed ID: 34826211
• A(H1N1)pdm09 Influenza Viruses Replicating in Ferret Upper or Lower Respiratory Tract Differed in Onward Transmission Potential by Air
  The Journal of Infectious Diseases. 01, 2022  |   Pubmed ID: 34036370
• Emerging SARS-CoV-2 Variants Expand Species Tropism to Murines
  EBioMedicine. Nov, 2021  |   Pubmed ID: 34689086
• Targeting Highly Pathogenic Coronavirus-induced Apoptosis Reduces Viral Pathogenesis and Disease Severity
  Science Advances. 06, 2021  |   Pubmed ID: 34134991
• Monocytic MDSC Mobilization Promotes Tumor Recurrence After Liver Transplantation Via CXCL10/TLR4/MMP14 Signaling
  Cell Death & Disease. 05, 2021  |   Pubmed ID: 33990548
• STAT2-dependent Restriction of Zika Virus by Human Macrophages but Not Dendritic Cells
  Emerging Microbes & Infections. Dec, 2021  |   Pubmed ID: 33979266
• Development of Cisplatin-loaded Hydrogels for Trans-portal Vein Chemoembolization in an Orthotopic Liver Cancer Mouse Model
  Drug Delivery. Dec, 2021  |   Pubmed ID: 33685316
• Robust SARS-CoV-2 Infection in Nasal Turbinates After Treatment with Systemic Neutralizing Antibodies
  Cell Host & Microbe. 04, 2021  |   Pubmed ID: 33657424
• Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th Edition)
  Autophagy. Feb, 2021  |   Pubmed ID: 33634751
• Human Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and Coronavirus
  Stem Cell Reports. 03, 2021  |   Pubmed ID: 33626333
• Development of Three-Dimensional Human Intestinal Organoids As a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses
  Biomedicines. Jan, 2021  |   Pubmed ID: 33477611
• Host and Viral Determinants for Efficient SARS-CoV-2 Infection of the Human Lung
  Nature Communications. 01, 2021  |   Pubmed ID: 33420022
• SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of COVID-19
  Cellular and Molecular Gastroenterology and Hepatology. 2021  |   Pubmed ID: 33010495
• Natural Transmission of Bat-like Severe Acute Respiratory Syndrome Coronavirus 2 Without Proline-Arginine-Arginine-Alanine Variants in Coronavirus Disease 2019 Patients
  Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. 07, 2021  |   Pubmed ID: 32649739
• Human Coronavirus Dependency on Host Heat Shock Protein 90 Reveals an Antiviral Target
  Emerging Microbes & Infections. Dec, 2020  |   Pubmed ID: 33179566
• Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters
  Cell Reports. Medicine. 10, 2020  |   Pubmed ID: 32984855
• Viruses Harness YxxØ Motif to Interact with Host AP2M1 for Replication: A Vulnerable Broad-spectrum Antiviral Target
  Science Advances. 08, 2020  |   Pubmed ID: 32923629
• Comparative Tropism, Replication Kinetics, and Cell Damage Profiling of SARS-CoV-2 and SARS-CoV with Implications for Clinical Manifestations, Transmissibility, and Laboratory Studies of COVID-19: an Observational Study
  The Lancet. Microbe. May, 2020  |   Pubmed ID: 32835326
• Attenuated Interferon and Proinflammatory Response in SARS-CoV-2-Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation
  The Journal of Infectious Diseases. 08, 2020  |   Pubmed ID: 32563187
• Infection of Bat and Human Intestinal Organoids by SARS-CoV-2
  Nature Medicine. 07, 2020  |   Pubmed ID: 32405028
• Targeting the Inositol-Requiring Enzyme-1 Pathway Efficiently Reverts Zika Virus-Induced Neurogenesis and Spermatogenesis Marker Perturbations
  ACS Infectious Diseases. 07, 2020  |   Pubmed ID: 32329611
• Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19
  Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. 09, 2020  |   Pubmed ID: 32270184
• Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages
  The Journal of Infectious Diseases. 02, 2020  |   Pubmed ID: 31562757
• A Novel Partial Lid for Mechanical Defeatherers Reduced Aerosol Dispersion During Processing of Avian Influenza Virus Infected Poultry
  PloS One. 2019  |   Pubmed ID: 31067261
• Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus As a Host-Targeting Antiviral Strategy
  International Journal of Molecular Sciences. Jan, 2019  |   Pubmed ID: 30658479
• SREBP-dependent Lipidomic Reprogramming As a Broad-spectrum Antiviral Target
  Nature Communications. 01, 2019  |   Pubmed ID: 30631056
• Establishment of a Lethal Aged Mouse Model of Human Respiratory Syncytial Virus Infection
  Antiviral Research. 01, 2019  |   Pubmed ID: 30503888
• Identification and Characterization of GLDC As Host Susceptibility Gene to Severe Influenza
  EMBO Molecular Medicine. 01, 2019  |   Pubmed ID: 30498026
• Dual-functional Peptide with Defective Interfering Genes Effectively Protects Mice Against Avian and Seasonal Influenza
  Nature Communications. 06, 2018  |   Pubmed ID: 29907765
• Differentiated Human Airway Organoids to Assess Infectivity of Emerging Influenza Virus
  Proceedings of the National Academy of Sciences of the United States of America. 06, 2018  |   Pubmed ID: 29891677
• Large-scale Sequence Analysis Reveals Novel Human-adaptive Markers in PB2 Segment of Seasonal Influenza A Viruses
  Emerging Microbes & Infections. Mar, 2018  |   Pubmed ID: 29593225
• Assessing the Risk of Downwind Spread of Avian Influenza Virus Via Airborne Particles from an Urban Wholesale Poultry Market
  Building and Environment. Jan, 2018  |   Pubmed ID: 29479134
• Defining the Sizes of Airborne Particles That Mediate Influenza Transmission in Ferrets
  Proceedings of the National Academy of Sciences of the United States of America. 03, 2018  |   Pubmed ID: 29463703
• Inhibitors of Influenza A Virus Polymerase
  ACS Infectious Diseases. 03, 2018  |   Pubmed ID: 29355011
• Genetic Analysis of H7N9 Highly Pathogenic Avian Influenza Virus in Guangdong, China, 2016-2017
  The Journal of Infection. 01, 2018  |   Pubmed ID: 28889968
• Antibody-Dependent Cell-Mediated Cytotoxicity Epitopes on the Hemagglutinin Head Region of Pandemic H1N1 Influenza Virus Play Detrimental Roles in H1N1-Infected Mice
  Frontiers in Immunology. 2017  |   Pubmed ID: 28377769
• Interplay Between SIRT1 and Hepatitis B Virus X Protein in the Activation of Viral Transcription
  Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. Apr, 2017  |   Pubmed ID: 28242208
• PB2 Substitutions V598T/I Increase the Virulence of H7N9 Influenza A Virus in Mammals
  Virology. 01, 2017  |   Pubmed ID: 27889648
• Identification of a Novel Small-molecule Compound Targeting the Influenza A Virus Polymerase PB1-PB2 Interface
  Antiviral Research. 01, 2017  |   Pubmed ID: 27840201
• Amino Acid Substitutions V63I or A37S/I61T/V63I/V100A in the PA N-terminal Domain Increase the Virulence of H7N7 Influenza A Virus
  Scientific Reports. 11, 2016  |   Pubmed ID: 27886255
• Peptide-Mediated Interference of PB2-eIF4G1 Interaction Inhibits Influenza A Viruses' Replication in Vitro and in Vivo
  ACS Infectious Diseases. 07, 2016  |   Pubmed ID: 27626099
• Isolation of H5N6, H7N9 and H9N2 Avian Influenza A Viruses from Air Sampled at Live Poultry Markets in China, 2014 and 2015
  Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin. Sep, 2016  |   Pubmed ID: 27608369
• MERS Coronavirus Induces Apoptosis in Kidney and Lung by Upregulating Smad7 and FGF2
  Nature Microbiology. Feb, 2016  |   Pubmed ID: 27572168
• Novel Residues in the PA Protein of Avian Influenza H7N7 Virus Affect Virulence in Mammalian Hosts
  Virology. 11, 2016  |   Pubmed ID: 27525812
• A Novel Small-molecule Compound Disrupts Influenza A Virus PB2 Cap-binding and Inhibits Viral Replication
  The Journal of Antimicrobial Chemotherapy. 09, 2016  |   Pubmed ID: 27272726
• Novel Mutations L228I and Y232H Cause Nonnucleoside Reverse Transcriptase Inhibitor Resistance in Combinational Pattern
  AIDS Research and Human Retroviruses. 09, 2016  |   Pubmed ID: 27067022
• A Novel Small-molecule Inhibitor of Influenza A Virus Acts by Suppressing PA Endonuclease Activity of the Viral Polymerase
  Scientific Reports. Mar, 2016  |   Pubmed ID: 26956222
• A Novel Peptide with Potent and Broad-spectrum Antiviral Activities Against Multiple Respiratory Viruses
  Scientific Reports. Feb, 2016  |   Pubmed ID: 26911565
• Quantification of Influenza Virus RNA in Aerosols in Patient Rooms
  PloS One. 2016  |   Pubmed ID: 26849130
• Identification of a Small-molecule Inhibitor of Influenza Virus Via Disrupting the Subunits Interaction of the Viral Polymerase
  Antiviral Research. Jan, 2016  |   Pubmed ID: 26593979
• Middle East Respiratory Syndrome Coronavirus Infection: Virus-host Cell Interactions and Implications on Pathogenesis
  Virology Journal. Dec, 2015  |   Pubmed ID: 26690369
• PExFInS: An Integrative Post-GWAS Explorer for Functional Indels and SNPs
  Scientific Reports. Nov, 2015  |   Pubmed ID: 26612672
• Transmission of H7N9 Influenza Viruses with a Polymorphism at PB2 Residue 627 in Chickens and Ferrets
  Journal of Virology. Oct, 2015  |   Pubmed ID: 26202239
• Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset
  The Journal of Infectious Diseases. Dec, 2015  |   Pubmed ID: 26198719
• Host Genes and Influenza Pathogenesis in Humans: an Emerging Paradigm
  Current Opinion in Virology. Oct, 2015  |   Pubmed ID: 26079652
• Cross-protection of Influenza A Virus Infection by a DNA Aptamer Targeting the PA Endonuclease Domain
  Antimicrobial Agents and Chemotherapy. Jul, 2015  |   Pubmed ID: 25918143
• Identification of TMPRSS2 As a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza
  The Journal of Infectious Diseases. Oct, 2015  |   Pubmed ID: 25904605
• Functional Variants Regulating LGALS1 (Galectin 1) Expression Affect Human Susceptibility to Influenza A(H7N9)
  Scientific Reports. Feb, 2015  |   Pubmed ID: 25687228
• Requirement of CRTC1 Coactivator for Hepatitis B Virus Transcription
  Nucleic Acids Research. Nov, 2014  |   Pubmed ID: 25300488
• Liver Grafts for Transplantation from Donors with Diabetes: an Analysis of the Scientific Registry of Transplant Recipients Database
  PloS One. 2014  |   Pubmed ID: 24847864
• Productive Replication of Middle East Respiratory Syndrome Coronavirus in Monocyte-derived Dendritic Cells Modulates Innate Immune Response
  Virology. Apr, 2014  |   Pubmed ID: 24725946
• Increased Expression of EIF5A2, Via Hypoxia or Gene Amplification, Contributes to Metastasis and Angiogenesis of Esophageal Squamous Cell Carcinoma
  Gastroenterology. Jun, 2014  |   Pubmed ID: 24561231
• Surfactant Protein B Gene Polymorphism is Associated with Severe Influenza
  Chest. Jun, 2014  |   Pubmed ID: 24337193
• Receptor Binding and Transmission Studies of H5N1 Influenza Virus in Mammals
  Emerging Microbes & Infections. Dec, 2013  |   Pubmed ID: 26038448
• Prioritizing Genes Responsible for Host Resistance to Influenza Using Network Approaches
  BMC Genomics. Nov, 2013  |   Pubmed ID: 24261899
• Investigation of Tumor Suppressing Function of CACNA2D3 in Esophageal Squamous Cell Carcinoma
  PloS One. 2013  |   Pubmed ID: 23560067
• A Functional Variation in CD55 Increases the Severity of 2009 Pandemic H1N1 Influenza A Virus Infection
  The Journal of Infectious Diseases. Aug, 2012  |   Pubmed ID: 22693232
• A Critical Role of IL-17 in Modulating the B-cell Response During H5N1 Influenza Virus Infection
  Cellular & Molecular Immunology. Nov, 2011  |   Pubmed ID: 21946434
• Krüppel-like Factor 15 Activates Hepatitis B Virus Gene Expression and Replication
  Hepatology (Baltimore, Md.). Jul, 2011  |   Pubmed ID: 21503941
• D225G Mutation in Hemagglutinin of Pandemic Influenza H1N1 (2009) Virus Enhances Virulence in Mice
  Experimental Biology and Medicine (Maywood, N.J.). Aug, 2010  |   Pubmed ID: 20660098
• 协会与中国人群乙型肝炎病毒的慢性感染候选易感基因位点。
  Journal of Medical Virology. Mar, 2010  |   Pubmed ID: 20087947
• Functional Dissection of an IFN-alpha/beta Receptor 1 Promoter Variant That Confers Higher Risk to Chronic Hepatitis B Virus Infection
  Journal of Hepatology. Aug, 2009  |   Pubmed ID: 19501422
• A Regulatory Polymorphism in Interferon-gamma Receptor 1 Promoter is Associated with the Susceptibility to Chronic Hepatitis B Virus Infection
  Immunogenetics. Jun, 2009  |   Pubmed ID: 19488747
• 多态性的 I 型干扰素受体 1 启动子和他们对慢性乙型肝炎病毒感染的影响。
  Journal of Hepatology. Feb, 2007  |   Pubmed ID: 17125879
• SARS-related Virus Predating SARS Outbreak, Hong Kong
  Emerging Infectious Diseases. Feb, 2004  |   Pubmed ID: 15030679