Mauricio J. Reginato Department of Biochemistry and Molecular Biology Drexel University College of Medicine Biography Publications Institution JoVE Articles Mauricio J. Reginato has not added a biography. If you are Mauricio J. Reginato and would like to personalize this page please email our Author Liaison for assistance. Publications O-GlcNAc Transferase Regulates Cancer Stem-like Potential of Breast Cancer Cells Molecular Cancer Research : MCR. 04, 2020 | Pubmed ID: 31974291 Fueling the Fire: Emerging Role of the Hexosamine Biosynthetic Pathway in Cancer BMC Biology. 07, 2019 | Pubmed ID: 31272438 Breast Cancer Brain Metastasis Response to Radiation After Microbubble Oxygen Delivery in a Murine Model Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Dec, 2019 | Pubmed ID: 31124171 O-GlcNAcylation: Key Regulator of Glycolytic Pathways Journal of Bioenergetics and Biomembranes. 06, 2018 | Pubmed ID: 29344764 Nutrient Sensor O-GlcNAc Transferase Controls Cancer Lipid Metabolism Via SREBP-1 Regulation Oncogene. 02, 2018 | Pubmed ID: 29059153 O-GlcNAcylation Regulates Breast Cancer Metastasis Via SIRT1 Modulation of FOXM1 Pathway Oncogene. 01, 2017 | Pubmed ID: 27345396 Proapoptotic Protein Bim Attenuates Estrogen-enhanced Survival in Lymphangioleiomyomatosis JCI Insight. Nov, 2016 | Pubmed ID: 27882343 O-GlcNAcylation in Cancer Biology: Linking Metabolism and Signaling Journal of Molecular Biology. 08, 2016 | Pubmed ID: 27343361 Progress Toward Overcoming Hypoxia-induced Resistance to Solid Tumor Therapy Cancer Management and Research. 2015 | Pubmed ID: 26316817 Emerging Microtubule Targets in Glioma Therapy Seminars in Pediatric Neurology. Mar, 2015 | Pubmed ID: 25976261 MTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer Molecular Cancer Research : MCR. May, 2015 | Pubmed ID: 25636967 Hypoxia/HIF1α Induces Lapatinib Resistance in ERBB2-positive Breast Cancer Cells Via Regulation of DUSP2 Oncotarget. Feb, 2015 | Pubmed ID: 25596742 EMT Transition Alters Interstitial Fluid Flow-Induced Signaling in ERBB2-Positive Breast Cancer Cells Molecular Cancer Research : MCR. Apr, 2015 | Pubmed ID: 25566992 Cancer Metabolism: Cross Talk Between Signaling and O-GlcNAcylation Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 25030920 O-GlcNAcylation Regulates Cancer Metabolism and Survival Stress Signaling Via Regulation of the HIF-1 Pathway Molecular Cell. Jun, 2014 | Pubmed ID: 24857547 Sticking to Sugars at the Metastatic Site: Sialyltransferase ST6GalNAc2 Acts As a Breast Cancer Metastasis Suppressor Cancer Discovery. Mar, 2014 | Pubmed ID: 24596201 Activated ERBB2/HER2 Licenses Sensitivity to Apoptosis Upon Endoplasmic Reticulum Stress Through a PERK-dependent Pathway Cancer Research. Mar, 2014 | Pubmed ID: 24453000 The Oncogene HER2/neu (ERBB2) Requires the Hypoxia-inducible Factor HIF-1 for Mammary Tumor Growth and Anoikis Resistance The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23585570 ERK2-regulated TIMP1 Induces Hyperproliferation of K-Ras(G12D)-transformed Pancreatic Ductal Cells Neoplasia (New York, N.Y.). Apr, 2013 | Pubmed ID: 23555182 Critical Role of O-Linked β-N-acetylglucosamine Transferase in Prostate Cancer Invasion, Angiogenesis, and Metastasis The Journal of Biological Chemistry. Mar, 2012 | Pubmed ID: 22275356 Constitutive K-RasG12D Activation of ERK2 Specifically Regulates 3D Invasion of Human Pancreatic Cancer Cells Via MMP-1 Molecular Cancer Research : MCR. Feb, 2012 | Pubmed ID: 22160930 Surviving Without Oxygen: Hypoxia Regulation of Mammary Morphogenesis and Anoikis Cell Cycle (Georgetown, Tex.). Jul, 2011 | Pubmed ID: 21670595 Hypoxia Suppression of Bim and Bmf Blocks Anoikis and Luminal Clearing During Mammary Morphogenesis Molecular Biology of the Cell. Nov, 2010 | Pubmed ID: 20861305 ErbB2 Requires Integrin Alpha5 for Anoikis Resistance Via Src Regulation of Receptor Activity in Human Mammary Epithelial Cells Journal of Cell Science. Apr, 2010 | Pubmed ID: 20332114 An Ex Vivo Brain Slice Model to Study and Target Breast Cancer Brain Metastatic Tumor Growth Lorela Ciraku1, Rebecca A. Moeller1, Emily M. Esquea1, Wiktoria A. Gocal1, Edward J. Hartsough2,4, Nicole L. Simone3,4, Joshua G. Jackson2, Mauricio J. Reginato1,4 1Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, 2Department of Pharmacology and Physiology, Drexel University College of Medicine, 3Department of Radiation Oncology, Thomas Jefferson University, 4Sidney Kimmel Cancer Center, Thomas Jefferson University JoVE 62617 Recherche en cancérologie
An Ex Vivo Brain Slice Model to Study and Target Breast Cancer Brain Metastatic Tumor Growth Lorela Ciraku1, Rebecca A. Moeller1, Emily M. Esquea1, Wiktoria A. Gocal1, Edward J. Hartsough2,4, Nicole L. Simone3,4, Joshua G. Jackson2, Mauricio J. Reginato1,4 1Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, 2Department of Pharmacology and Physiology, Drexel University College of Medicine, 3Department of Radiation Oncology, Thomas Jefferson University, 4Sidney Kimmel Cancer Center, Thomas Jefferson University JoVE 62617 Recherche en cancérologie