Nancy Kedersha Division of Rheumatology, Immunology, and Allergy Brigham and Women's Hospital Biography Publications Institution JoVE Articles Nancy Kedersha has not added a biography. If you are Nancy Kedersha and would like to personalize this page please email our Author Liaison for assistance. Publications Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics Molecular Cell. Mar, 2017 | Pubmed ID: 28306503 Stress-specific Differences in Assembly and Composition of Stress Granules and Related Foci Journal of Cell Science. Mar, 2017 | Pubmed ID: 28096475 Ebola Virus Does Not Induce Stress Granule Formation During Infection and Sequesters Stress Granule Proteins Within Viral Inclusions Journal of Virology. Aug, 2016 | Pubmed ID: 27252530 Mammalian Ataxin-2 Modulates Translation Control at the Pre-initiation Complex Via PI3K/mTOR and is Induced by Starvation Biochimica Et Biophysica Acta. Sep, 2016 | Pubmed ID: 27240544 YB-1 Regulates TiRNA-induced Stress Granule Formation but Not Translational Repression Nucleic Acids Research. Aug, 2016 | Pubmed ID: 27174937 Vinca Alkaloid Drugs Promote Stress-induced Translational Repression and Stress Granule Formation Oncotarget. May, 2016 | Pubmed ID: 27083003 G3BP-Caprin1-USP10 Complexes Mediate Stress Granule Condensation and Associate with 40S Subunits The Journal of Cell Biology. Mar, 2016 | Pubmed ID: 27022092 Methods for the Characterization of Stress Granules in Virus Infected Cells Methods (San Diego, Calif.). Nov, 2015 | Pubmed ID: 25896634 Stress Granules Regulate Double-stranded RNA-dependent Protein Kinase Activation Through a Complex Containing G3BP1 and Caprin1 MBio. Mar, 2015 | Pubmed ID: 25784705 Viral and Cellular Proteins Containing FGDF Motifs Bind G3BP to Block Stress Granule Formation PLoS Pathogens. Feb, 2015 | Pubmed ID: 25658430 Stress Granules, P-bodies and Cancer Biochimica Et Biophysica Acta. Jul, 2015 | Pubmed ID: 25482014 Activation of Stress Response Pathways Promotes Formation of Antiviral Granules and Restricts Virus Replication Molecular and Cellular Biology. Jun, 2014 | Pubmed ID: 24662051 Dysregulated Expression of Lipid Storage and Membrane Dynamics Factors in Tia1 Knockout Mouse Nervous Tissue Neurogenetics. May, 2014 | Pubmed ID: 24659297 Stress Granules and Cell Signaling: More Than Just a Passing Phase? Trends in Biochemical Sciences. Oct, 2013 | Pubmed ID: 24029419 Relationship of GW/P-bodies with Stress Granules Advances in Experimental Medicine and Biology. 2013 | Pubmed ID: 23224972 Stress Puts TIA on TOP Genes & Development. Oct, 2011 | Pubmed ID: 22012617 Visualization of Single MRNAs Reveals Temporal Association of Proteins with MicroRNA-regulated MRNA Nucleic Acids Research. Sep, 2011 | Pubmed ID: 21653551 Fast Kinase Domain-containing Protein 3 is a Mitochondrial Protein Essential for Cellular Respiration Biochemical and Biophysical Research Communications. Oct, 2010 | Pubmed ID: 20869947 Angiogenin-induced TRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20129916 Regulation of Translation by Stress Granules and Processing Bodies Progress in Molecular Biology and Translational Science. 2009 | Pubmed ID: 20374741 Metazoan Stress Granule Assembly is Mediated by P-eIF2alpha-dependent and -independent Mechanisms RNA (New York, N.Y.). Oct, 2009 | Pubmed ID: 19661161 Stress Granules Current Biology : CB. May, 2009 | Pubmed ID: 19467203 RNA Granules: Post-transcriptional and Epigenetic Modulators of Gene Expression Nature Reviews. Molecular Cell Biology. Jun, 2009 | Pubmed ID: 19461665 Identification of a Cytoplasmic Complex That Adds a Cap Onto 5'-monophosphate RNA Molecular and Cellular Biology. Apr, 2009 | Pubmed ID: 19223470 Real-time and Quantitative Imaging of Mammalian Stress Granules and Processing Bodies Methods in Enzymology. 2008 | Pubmed ID: 19111193 A Functional RNAi Screen Links O-GlcNAc Modification of Ribosomal Proteins to Stress Granule and Processing Body Assembly Nature Cell Biology. Oct, 2008 | Pubmed ID: 18794846 Autoantibodies to the Translational Suppressors T Cell Intracytoplasmic Antigen 1 and T Cell Intracytoplasmic Antigen 1-related Protein in Patients with Rheumatic Diseases: Increased Prevalence in Systemic Lupus Erythematosus and Systemic Sclerosis and Correlation with Clinical Features Arthritis and Rheumatism. May, 2008 | Pubmed ID: 18438838 Stress Granules: the Tao of RNA Triage Trends in Biochemical Sciences. Mar, 2008 | Pubmed ID: 18291657 Mammalian Stress Granules and Processing Bodies Methods in Enzymology. 2007 | Pubmed ID: 17923231 T-cell Intracellular Antigen-1 (TIA-1)-induced Translational Silencing Promotes the Decay of Selected MRNAs The Journal of Biological Chemistry. Oct, 2007 | Pubmed ID: 17711853 Elucidation of a C-rich Signature Motif in Target MRNAs of RNA-binding Protein TIAR Molecular and Cellular Biology. Oct, 2007 | Pubmed ID: 17682065 Ribosomal Slowdown Mediates Translational Arrest During Cellular Division Molecular and Cellular Biology. Oct, 2007 | Pubmed ID: 17664278 Fas-activated Serine/threonine Phosphoprotein (FAST) is a Regulator of Alternative Splicing Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17592127 On Again, off Again: the SRC-3 Transcriptional Coactivator Moonlights As a Translational Corepressor Molecular Cell. Mar, 2007 | Pubmed ID: 17386257 Polysome-bound Endonuclease PMR1 is Targeted to Stress Granules Via Stress-specific Binding to TIA-1 Molecular and Cellular Biology. Dec, 2006 | Pubmed ID: 16982678 Eukaryotic Initiation Factor 2alpha-independent Pathway of Stress Granule Induction by the Natural Product Pateamine A The Journal of Biological Chemistry. Oct, 2006 | Pubmed ID: 16951406 RNA Granules The Journal of Cell Biology. Mar, 2006 | Pubmed ID: 16520386 Stress Granules and Processing Bodies Are Dynamically Linked Sites of MRNP Remodeling The Journal of Cell Biology. Jun, 2005 | Pubmed ID: 15967811 Importance of EIF2alpha Phosphorylation and Stress Granule Assembly in Alphavirus Translation Regulation Molecular Biology of the Cell. Aug, 2005 | Pubmed ID: 15930128 Heme-regulated Inhibitor Kinase-mediated Phosphorylation of Eukaryotic Translation Initiation Factor 2 Inhibits Translation, Induces Stress Granule Formation, and Mediates Survival Upon Arsenite Exposure The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15684421 Mystique is a New Insulin-like Growth Factor-I-regulated PDZ-LIM Domain Protein That Promotes Cell Attachment and Migration and Suppresses Anchorage-independent Growth Molecular Biology of the Cell. Apr, 2005 | Pubmed ID: 15659642 FAST is a Survival Protein That Senses Mitochondrial Stress and Modulates TIA-1-regulated Changes in Protein Expression Molecular and Cellular Biology. Dec, 2004 | Pubmed ID: 15572676 Stress Granule Assembly is Mediated by Prion-like Aggregation of TIA-1 Molecular Biology of the Cell. Dec, 2004 | Pubmed ID: 15371533 FAST is a BCL-X(L)-associated Mitochondrial Protein Biochemical and Biophysical Research Communications. May, 2004 | Pubmed ID: 15110758 Post-transcriptional Regulation of Proinflammatory Proteins Journal of Leukocyte Biology. Jul, 2004 | Pubmed ID: 15075353 MK2-induced Tristetraprolin:14-3-3 Complexes Prevent Stress Granule Association and ARE-mRNA Decay The EMBO Journal. Mar, 2004 | Pubmed ID: 15014438 Arthritis Suppressor Genes TIA-1 and TTP Dampen the Expression of Tumor Necrosis Factor Alpha, Cyclooxygenase 2, and Inflammatory Arthritis Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14769925 Granzyme B Leakage-induced Cell Death: a New Type of Activation-induced Natural Killer Cell Death European Journal of Immunology. Dec, 2003 | Pubmed ID: 14635036 Vaults Bind Directly to Microtubules Via Their Caps and Not Their Barrels Cell Motility and the Cytoskeleton. Dec, 2003 | Pubmed ID: 14584025 U1 SnRNP-dependent Function of TIAR in the Regulation of Alternative RNA Processing of the Human Calcitonin/CGRP Pre-mRNA Molecular and Cellular Biology. Sep, 2003 | Pubmed ID: 12917321 Regulation of Cyclooxygenase-2 Expression by the Translational Silencer TIA-1 The Journal of Experimental Medicine. Aug, 2003 | Pubmed ID: 12885872 Visibly Stressed: the Role of EIF2, TIA-1, and Stress Granules in Protein Translation Cell Stress & Chaperones. Apr, 2002 | Pubmed ID: 12380690 Sendai Virus Trailer RNA Binds TIAR, a Cellular Protein Involved in Virus-induced Apoptosis The EMBO Journal. Oct, 2002 | Pubmed ID: 12356730 Stressful Initiations Journal of Cell Science. Aug, 2002 | Pubmed ID: 12140254 Evidence That Ternary Complex (eIF2-GTP-tRNA(i)(Met))-deficient Preinitiation Complexes Are Core Constituents of Mammalian Stress Granules Molecular Biology of the Cell. Jan, 2002 | Pubmed ID: 11809833 Methoden om Cytoplasmatische Foci te classificeren als Mammalian Stress Granules Anaïs Aulas*1,2, Marta M. Fay*1,2, Witold Szaflarski1,2,3, Nancy Kedersha1,2, Paul Anderson1,2, Pavel Ivanov1,2,4 1Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, 2Department of Medicine, Harvard Medical School, 3Department of Histology and Embryology, Poznan University of Medical Sciences, 4The Broad Institute of Harvard and M.I.T. JoVE 55656 Biologie
Methoden om Cytoplasmatische Foci te classificeren als Mammalian Stress Granules Anaïs Aulas*1,2, Marta M. Fay*1,2, Witold Szaflarski1,2,3, Nancy Kedersha1,2, Paul Anderson1,2, Pavel Ivanov1,2,4 1Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, 2Department of Medicine, Harvard Medical School, 3Department of Histology and Embryology, Poznan University of Medical Sciences, 4The Broad Institute of Harvard and M.I.T. JoVE 55656 Biologie