Naoto Hirano Department of Immunology University of Toronto Biography Publications Institution JoVE Articles Naoto Hirano has not added a biography. If you are Naoto Hirano and would like to personalize this page please email our Author Liaison for assistance. Publications BET Bromodomain Inhibition Enhances T Cell Persistence and Function in Adoptive Immunotherapy Models The Journal of Clinical Investigation. Sep, 2016 | Pubmed ID: 27548527 Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors PloS One. 2016 | Pubmed ID: 27213277 CD4(+) and CD8(+) TCRβ Repertoires Possess Different Potentials to Generate Extraordinarily High-avidity T Cells Scientific Reports. Mar, 2016 | Pubmed ID: 27030642 CDR3β Sequence Motifs Regulate Autoreactivity of Human Invariant NKT Cell Receptors Journal of Autoimmunity. Apr, 2016 | Pubmed ID: 26748722 Adoptive T Cell Therapy Targeting CD1 and MR1 Frontiers in Immunology. 2015 | Pubmed ID: 26052329 Optimization of T-cell Reactivity by Exploiting TCR Chain Centricity for the Purpose of Safe and Effective Antitumor TCR Gene Therapy Cancer Immunology Research. Sep, 2015 | Pubmed ID: 25943533 Specific Roles of Each TCR Hemichain in Generating Functional Chain-centric TCR Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015 | Pubmed ID: 25710913 Human Cell-based Artificial Antigen-presenting Cells for Cancer Immunotherapy Immunological Reviews. Jan, 2014 | Pubmed ID: 24329798 使用自体 CD4 T 细胞的 CD8 T 细胞体外扩增的帮助。 PloS One. 2012 | Pubmed ID: 22279573 IL 21 可以在人类的 CD8 + T 细胞中的 STAT 3 依赖方式补充次优荔枝独立 MAPK 激活。 Journal of Immunology (Baltimore, Md. : 1950). Feb, 2012 | Pubmed ID: 22238455 [The Cutting Edge of Antitumor Adoptive Cell Therapy] [Rinsho Ketsueki] The Japanese Journal of Clinical Hematology. Oct, 2011 | Pubmed ID: 21971251 HLA DP4 限制反存活 Th1 和 Th2 响应使用人工抗原递呈细胞的诱导。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2011 | Pubmed ID: 21705450 The Third Consensus Conference on the Treatment of Aplastic Anemia International Journal of Hematology. Jun, 2011 | Pubmed ID: 21617886 建立在人类身上使用体外受 CD8 + T 细胞中的抗肿瘤内存。 Science Translational Medicine. Apr, 2011 | Pubmed ID: 21525398 一个小组的人类细胞为基础的人工 APC 使扩大的长寿抗原特异性 CD4 + T 细胞受到普遍的 HLA 等位基因的限制。 International Immunology. Nov, 2010 | Pubmed ID: 21059769 Juvenile Myelomonocytic Leukemia: Epidemiology, Etiopathogenesis, Diagnosis, and Management Considerations Paediatric Drugs. 2010 | Pubmed ID: 20034338 解离其对立的免疫调节作用的是优化抗肿瘤诱导白细胞介素 21 的 CD8 + T 细胞反应的关键。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2008 | Pubmed ID: 18829491 Clinical Impact of HLA-DR15, a Minor Population of Paroxysmal Nocturnal Haemoglobinuria-type Cells, and an Aplastic Anaemia-associated Autoantibody in Children with Acquired Aplastic Anaemia British Journal of Haematology. Jul, 2008 | Pubmed ID: 18537977 长寿命抗肿瘤 CD8 + 淋巴细胞养疗法使用人工抗原递呈细胞生成。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2007 | Pubmed ID: 17363542 Volcanism in Response to Plate Flexure Science (New York, N.Y.). Sep, 2006 | Pubmed ID: 16873612 CD8 + T 细胞抗原表位的免疫原性鉴定来自 γ-珠蛋白,假定的肿瘤相关抗原的少年细胞性白血病。 Blood. Oct, 2006 | Pubmed ID: 16778141 有效演示文稿的自然加工 HLA I 类多肽的研究人工抗原递呈细胞有效的抗肿瘤反应的一代。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2006 | Pubmed ID: 16707591 参与 CD83 配体诱导长期的扩张的 CD8 + T 细胞和优惠丰富的抗原特异性。 Blood. Feb, 2006 | Pubmed ID: 16239433 The Chemical Structure of the Hawaiian Mantle Plume Nature. Aug, 2005 | Pubmed ID: 16100780 日本再生障碍性贫血患者的抗 Kinectin 和抗 PMS1 抗体的存在。 British Journal of Haematology. Jan, 2005 | Pubmed ID: 15638857 常检测到的再生障碍性贫血患者的自身抗体。 Blood. Dec, 2003 | Pubmed ID: 12947009 共享的肿瘤相关抗原细胞色素 P450 氧化 1B1 已识别特定的细胞毒性 T 细胞。 Blood. Nov, 2003 | Pubmed ID: 12869499 人类的小学和记忆细胞毒 T 淋巴细胞反应被有效地诱导通过 CD40 激活 B 细胞的抗原递呈细胞: 潜在的临床应用。 Blood. May, 2002 | Pubmed ID: 11964299 发电 Tingxi Guo1,2, Toshiki Ochi*2, Munehide Nakatsugawa*2, Yuki Kagoya2, Mark Anczurowski1,2, Chung-Hsi Wang1,2, Muhammed A. Rahman2, Kayoko Saso2, Marcus O. Butler1,2, Naoto Hirano1,2 1Department of Immunology, University of Toronto, 2Princess Margaret Cancer Centre, University Health Network JoVE 54697 Immunologie et Infection
发电 Tingxi Guo1,2, Toshiki Ochi*2, Munehide Nakatsugawa*2, Yuki Kagoya2, Mark Anczurowski1,2, Chung-Hsi Wang1,2, Muhammed A. Rahman2, Kayoko Saso2, Marcus O. Butler1,2, Naoto Hirano1,2 1Department of Immunology, University of Toronto, 2Princess Margaret Cancer Centre, University Health Network JoVE 54697 Immunologie et Infection