Petr Džubák Institute of Molecular and Translational Medicine Palacky University in Olomouc Biography Publications Institution JoVE Articles Petr Džubák has not added a biography. If you are Petr Džubák and would like to personalize this page please email our Author Liaison for assistance. Publications Synthesis and Cytostatic and Antiviral Profiling of Thieno-fused 7-Deazapurine Ribonucleosides Journal of Medicinal Chemistry. Feb, 2017 | Pubmed ID: 28221790 Cytotoxic Conjugates of Betulinic Acid and Substituted Triazoles Prepared by Huisgen Cycloaddition from 30-azidoderivatives PloS One. 2017 | Pubmed ID: 28158265 The Natural Cytokinin 2OH3MeOBAR Induces Cell Death by a Mechanism That is Different from That of the "classical" Cytokinin Ribosides Phytochemistry. Apr, 2017 | Pubmed ID: 28153445 Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid ChemMedChem. Jan, 2017 | Pubmed ID: 28084676 Cell-based DNA Demethylation Detection System for Screening of Epigenetic Drugs in 2D, 3D, and Xenograft Models Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Feb, 2017 | Pubmed ID: 27911980 Trilobolide-steroid Hybrids: Synthesis, Cytotoxic and Antimycobacterial Activity Steroids. Jan, 2017 | Pubmed ID: 27543674 Role of Salmonella Typhi Vi Antigen and Secretory Systems on Immune Response Current Pharmaceutical Design. 2016 | Pubmed ID: 27573929 The Dual Role of Asporin in Breast Cancer Progression Oncotarget. Aug, 2016 | Pubmed ID: 27409832 Lupane and 18α-oleanane Derivatives Substituted in the Position 2, Their Cytotoxicity and Influence on Cancer Cells European Journal of Medicinal Chemistry. Oct, 2016 | Pubmed ID: 27236068 Reproducibility of Uniform Spheroid Formation in 384-Well Plates: The Effect of Medium Evaporation Journal of Biomolecular Screening. Oct, 2016 | Pubmed ID: 27226477 Biodegradable System for Drug Delivery of Hydrolytically Labile Azanucleoside Drugs Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. Jun, 2016 | Pubmed ID: 27003313 Effects of Ginger Phenylpropanoids and Quercetin on Nrf2-ARE Pathway in Human BJ Fibroblasts and HaCaT Keratinocytes BioMed Research International. 2016 | Pubmed ID: 26942188 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action Molecular Cancer Therapeutics. May, 2016 | Pubmed ID: 26819331 Synthesis and Biological Profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides Bioorganic & Medicinal Chemistry. Dec, 2015 | Pubmed ID: 26558518 Preparation of Conjugates of Cytotoxic Lupane Triterpenes with Biotin Bioconjugate Chemistry. Dec, 2015 | Pubmed ID: 26537839 Synthesis of Cytotoxic 2,2-difluoroderivatives of Dihydrobetulinic Acid and Allobetulin and Study of Their Impact on Cancer Cells European Journal of Medicinal Chemistry. 2015 | Pubmed ID: 25942059 Caffeine-hydrazones As Anticancer Agents with Pronounced Selectivity Toward T-lymphoblastic Leukaemia Cells Bioorganic Chemistry. Jun, 2015 | Pubmed ID: 25912310 2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity ChemMedChem. Jun, 2015 | Pubmed ID: 25882678 Synthesis and Biological Activity Evaluation of Hydrazone Derivatives Based on a Tröger's Base Skeleton Bioorganic & Medicinal Chemistry. Apr, 2015 | Pubmed ID: 25737088 Affinity-based Methods in Drug-target Discovery Current Drug Targets. 2015 | Pubmed ID: 25410410 Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides Journal of Medicinal Chemistry. Oct, 2014 | Pubmed ID: 25259627 Hepcidin Levels in Diamond-Blackfan Anemia Reflect Erythropoietic Activity and Transfusion Dependency Haematologica. Jul, 2014 | Pubmed ID: 24727814 Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-substituted 7-(het)aryl-7-deazapurine Ribonucleosides Journal of Medicinal Chemistry. Feb, 2014 | Pubmed ID: 24397620 Combination of Prednisolone and Low Dosed Dexamethasone Exhibits Greater in Vitro Antileukemic Activity Than Equiactive Dose of Prednisolone and Overcomes Prednisolone Drug Resistance in Acute Childhood Lymphoblastic Leukemia Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. Sep, 2014 | Pubmed ID: 23128824 Preparation, Preliminary Screening of New Types of Steroid Conjugates and Their Activities on Steroid Receptors Steroids. Mar, 2013 | Pubmed ID: 23291595 Cancer Cell Response to Anthracyclines Effects: Mysteries of the Hidden Proteins Associated with These Drugs International Journal of Molecular Sciences. Nov, 2012 | Pubmed ID: 23443080 Cytotoxic Heterocyclic Triterpenoids Derived from Betulin and Betulinic Acid Bioorganic & Medicinal Chemistry. Jun, 2012 | Pubmed ID: 22551630 Aurora Kinase Inhibitors: Progress Towards the Clinic Investigational New Drugs. Dec, 2012 | Pubmed ID: 22350019 Synthesis of Various 5-alkoxymethyluracil Analogues and Structure-cytotoxic Activity Relationship Study Carbohydrate Research. Oct, 2011 | Pubmed ID: 21864833 Synthesis and Significant Cytostatic Activity of 7-hetaryl-7-deazaadenosines Journal of Medicinal Chemistry. Aug, 2011 | Pubmed ID: 21711054 2-phenylsubstituted-3-hydroxyquinolin-4(1H)-one-carboxamides: Structure-cytotoxic Activity Relationship Study ACS Combinatorial Science. Jan, 2011 | Pubmed ID: 21247123 Synthesis of 5-[alkoxy-(4-nitro-phenyl)-methyl]-uridines and Study of Their Cytotoxic Activity European Journal of Medicinal Chemistry. Sep, 2010 | Pubmed ID: 20605656 Anticancer Activity of Natural Cytokinins: a Structure-activity Relationship Study Phytochemistry. Aug, 2010 | Pubmed ID: 20553699 6-(Het)aryl-7-deazapurine Ribonucleosides As Novel Potent Cytostatic Agents Journal of Medicinal Chemistry. Jan, 2010 | Pubmed ID: 19929004 Utilization of High-accuracy FTICR-MS Data in Protein Quantitation Experiments Journal of Mass Spectrometry : JMS. Nov, 2009 | Pubmed ID: 19536796 The Anti-inflammatory Effects of Inhaled Corticosteroids Versus Anti-leukotrienes on the Lymphocyte P-glycoprotein (PGP) Expression in Asthmatic Children The Journal of Asthma : Official Journal of the Association for the Care of Asthma. May, 2009 | Pubmed ID: 19484671 Functional P53 in Cells Contributes to the Anticancer Effect of the Cyclin-dependent Kinase Inhibitor Roscovitine Journal of Cellular Biochemistry. Jun, 2009 | Pubmed ID: 19308936 Cyclocondensation Reaction of Heterocyclic Carbonyl Compounds. Part XIII: Synthesis and Cytotoxic Activity of Some 3,7-diaryl-5-(3,4,5-trimethoxyphenyl)pyrazolo[4,3-e][1,2,4]triazines European Journal of Medicinal Chemistry. Feb, 2009 | Pubmed ID: 18632190 Aurora Kinases: Structure, Functions and Their Association with Cancer Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. Jun, 2008 | Pubmed ID: 18795071 Synthesis and Cytotoxic Activity of Various 5-[alkoxy-(4-nitro-phenyl)-methyl]-uracils in Their Racemic Form Bioorganic & Medicinal Chemistry Letters. Dec, 2007 | Pubmed ID: 17935983 4-arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects Journal of Medicinal Chemistry. Nov, 2006 | Pubmed ID: 17064068 Comblike Dendrimers Containing Tn Antigen Modulate Natural Killing and Induce the Production of Tn Specific Antibodies Journal of Medicinal Chemistry. Oct, 2006 | Pubmed ID: 17034145 Pharmacological Activities of Natural Triterpenoids and Their Therapeutic Implications Natural Product Reports. Jun, 2006 | Pubmed ID: 16741586 New Derivatives of Silybin and 2,3-dehydrosilybin and Their Cytotoxic and P-glycoprotein Modulatory Activity Bioorganic & Medicinal Chemistry. Jun, 2006 | Pubmed ID: 16466920 Influence of Esterification and Modification of A-ring in a Group of Lupane Acids on Their Cytotoxicity Bioorganic & Medicinal Chemistry. Oct, 2005 | Pubmed ID: 16087342 Protein Fingerprints of Anti-cancer Effects of Cyclin-dependent Kinase Inhibition: Identification of Candidate Biomarkers Using 2-D Liquid Phase Separation Coupled to Mass Spectrometry Technology in Cancer Research & Treatment. Aug, 2005 | Pubmed ID: 16029063 Synthesis of Phthalates of Betulinic Acid and Betulin with Cytotoxic Activity Bioorganic & Medicinal Chemistry. May, 2005 | Pubmed ID: 15848757 The Synthetic Ligand of Peroxisome Proliferator-activated Receptor-gamma Ciglitazone Affects Human Glioblastoma Cell Lines The Journal of Pharmacology and Experimental Therapeutics. Jun, 2004 | Pubmed ID: 14988421 New Lupane Derived Compounds with Pro-apoptotic Activity in Cancer Cells: Synthesis and Structure-activity Relationships Journal of Medicinal Chemistry. Dec, 2003 | Pubmed ID: 14640549 Analysis of State-specific Phosphorylation of Proteins by Two-dimensional Gel Electrophoresis Approach Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Apr, 2003 | Pubmed ID: 12659733 Application of Proteomics in the Search for Novel Proteins Associated with the Anti-cancer Effect of the Synthetic Cyclin-dependent Kinases Inhibitor, Bohemine Technology in Cancer Research & Treatment. Aug, 2002 | Pubmed ID: 12625783 Fordampning-reducerende Kultur Betingelse Øger Reproducerbarhed af flercellet Sfæroide Formation i mikrotiterplader Viswanath Das1, Tomáš Fürst1, Soňa Gurská1, Petr Džubák1, Marián Hajdúch1 1Institute of Molecular and Translational Medicine, Palacky University in Olomouc JoVE 55403 Recherche en cancérologie
Fordampning-reducerende Kultur Betingelse Øger Reproducerbarhed af flercellet Sfæroide Formation i mikrotiterplader Viswanath Das1, Tomáš Fürst1, Soňa Gurská1, Petr Džubák1, Marián Hajdúch1 1Institute of Molecular and Translational Medicine, Palacky University in Olomouc JoVE 55403 Recherche en cancérologie