Steven L. Carroll Department of Pathology and Laboratory Medicine Medical University of South Carolina Biography Publications Institution JoVE Articles Steven L. Carroll has not added a biography. If you are Steven L. Carroll and would like to personalize this page please email our Author Liaison for assistance. Publications Down Syndrome Biobank Consortium: A Perspective Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Mar, 2024 | Pubmed ID: 38270275 Inhibition of Erb-B2 Receptor Tyrosine Kinase 3 and Associated Regulatory Pathways Potently Impairs Malignant Peripheral Nerve Sheath Tumor Proliferation and Survival The American Journal of Pathology. Sep, 2023 | Pubmed ID: 37328102 LPAR1 and Aberrantly Expressed LPAR3 Differentially Promote the Migration and Proliferation of Malignant Peripheral Nerve Sheath Tumor Cells Glia. Mar, 2023 | Pubmed ID: 36416236 Priorities in Biobanking Research: A Report on the 2021 ISBER Round Table Biopreservation and Biobanking. Feb, 2023 | Pubmed ID: 35507966 Developmental, Neurochemical, and Behavioral Analyses of ErbB4 Cyt-1 Knockout Mice Journal of Neurochemistry. Jun, 2022 | Pubmed ID: 35523590 The RASopathies: Biology, Genetics and Therapeutic Options Advances in Cancer Research. 2022 | Pubmed ID: 35101235 Suppression of Fli-1 Protects Against Pericyte Loss and Cognitive Deficits in Alzheimer's Disease Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2022 | Pubmed ID: 35038582 R-Ras Subfamily Proteins Elicit Distinct Physiologic Effects and Phosphoproteome Alterations in Neurofibromin-null MPNST Cells Cell Communication and Signaling : CCS. Sep, 2021 | Pubmed ID: 34530870 The Role of R-Ras Proteins in Normal and Pathologic Migration and Morphologic Change The American Journal of Pathology. Sep, 2021 | Pubmed ID: 34111428 The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment International Journal of Molecular Sciences. Apr, 2021 | Pubmed ID: 33925820 Establishment and Genomic Characterization of a Sporadic Malignant Peripheral Nerve Sheath Tumor Cell Line Scientific Reports. Mar, 2021 | Pubmed ID: 33707600 Each Patient is a Research Biorepository: Informatics-enabled Research on Surplus Clinical Specimens Via the Living BioBank Journal of the American Medical Informatics Association : JAMIA. 01, 2021 | Pubmed ID: 33166379 Chemoembolizing Hepatocellular Carcinoma with Microsphere Cored with Arsenic Trioxide Microcrystal Drug Delivery. Nov, 2020 | Pubmed ID: 33307843 Assessing Interobserver Variability and Accuracy in the Histological Diagnosis and Classification of Cutaneous Neurofibromass Neuro-oncology Advances. Jul, 2020 | Pubmed ID: 32642737 Serum Pro-BDNF Levels Correlate with Phospho-tau Staining in Alzheimer's Disease Neurobiology of Aging. 03, 2020 | Pubmed ID: 31882186 Salinomycin Targets the Genome of Radioresistant Cells in Glioblastomas Neuro-oncology. 02, 2020 | Pubmed ID: 31784742 The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease Molecular & Cellular Proteomics : MCP. 01, 2020 | Pubmed ID: 31699905 Mechanisms of Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Action in Human Neoplasia The American Journal of Pathology. 10, 2019 | Pubmed ID: 31351986 ErbB4 Promotes Malignant Peripheral Nerve Sheath Tumor Pathogenesis Via Ras-independent Mechanisms Cell Communication and Signaling : CCS. 07, 2019 | Pubmed ID: 31291965 The Evolution and Multi-molecular Properties of NF1 Cutaneous Neurofibromas Originating from C-fiber Sensory Endings and Terminal Schwann Cells at Normal Sites of Sensory Terminations in the Skin PloS One. 2019 | Pubmed ID: 31107888 Complex Patterns of GABAergic Neuronal Deficiency and Type 2 Potassium-Chloride Cotransporter Immaturity in Human Focal Cortical Dysplasia Journal of Neuropathology and Experimental Neurology. 04, 2019 | Pubmed ID: 30856249 Cutaneous Neurofibromas: Current Clinical and Pathologic Issues Neurology. 07, 2018 | Pubmed ID: 29987130 Oridonin Inhibits Aberrant AKT Activation in Breast Cancer Oncotarget. May, 2018 | Pubmed ID: 29844859 Pathology of NNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease Neuroscience. 08, 2018 | Pubmed ID: 29782905 Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms Advances in Anatomic Pathology. Sep, 2018 | Pubmed ID: 29762158 Rare Coding Variants in PLCG2, ABI3, and TREM2 Implicate Microglial-mediated Innate Immunity in Alzheimer's Disease Nature Genetics. 09, 2017 | Pubmed ID: 28714976 The Molecular and Morphologic Structures That Make Saltatory Conduction Possible in Peripheral Nerve Journal of Neuropathology and Experimental Neurology. 04, 2017 | Pubmed ID: 28340093 BH3 Mimetics Suppress CXCL12 Expression in Human Malignant Peripheral Nerve Sheath Tumor Cells Oncotarget. Jan, 2017 | Pubmed ID: 28055968 Neuronal Exosomes Reveal Alzheimer's Disease Biomarkers in Down Syndrome Alzheimer's & Dementia : the Journal of the Alzheimer's Association. May, 2017 | Pubmed ID: 27755974 Current Status and Recommendations for Biomarkers and Biobanking in Neurofibromatosis Neurology. Aug, 2016 | Pubmed ID: 27527649 STAT1 and NF-κB Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells Molecular Cancer Research : MCR. 05, 2016 | Pubmed ID: 26883073 The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors As a Paradigm for Cross-Species Comparative Oncogenomics The American Journal of Pathology. Mar, 2016 | Pubmed ID: 26740486 Classic Ras Proteins Promote Proliferation and Survival Via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells Journal of Neuropathology and Experimental Neurology. Jun, 2015 | Pubmed ID: 25946318 Combinatorial Therapy with Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades Journal of Neuropathology and Experimental Neurology. Nov, 2014 | Pubmed ID: 25289889 일반적인 유전자 변형 CLDN2 고 PRSS1 PRSS2 Loci 알코올 관련 및 산발적 인 췌 장 염에 대 한 위험 변경 Nature Genetics. Nov, 2012 | Pubmed ID: 23143602 팬 ErbB 억제제 PD168393 악성 말 초 신경 칼 집 종양 세포에서 Lysosomal 부전 유발 Apoptotic 죽음을 향상 시킵니다 Neuro-oncology. Jan, 2012 | Pubmed ID: 22259051 분자 메커니즘 Schwann 세포 Neoplasms의 Pathogenesis 홍보 Acta Neuropathologica. Dec, 2011 | Pubmed ID: 22160322 유전자 조작된 마우스 모델 Neurofibromatosis 유형 나 관련 Neoplasms 말 초 신 경계의 Pathogenesis에 새로운 빛을 나타냈다 Brain Research Bulletin. Aug, 2011 | Pubmed ID: 21855613 MS4A4/MS4A6E, CD2AP, CD33 및 Epha1에서 일반적인 변종 늦은 개시 Alzheimer의 질병에 연결 됩니다 Nature Genetics. May, 2011 | Pubmed ID: 21460841 Tamoxifen에 스 트로 겐 수용 체-독립적인 방식으로 악성 말 초 신경 칼 집 종양의 성장을 억제 한다 Neuro-oncology. Jan, 2011 | Pubmed ID: 21075781 7 P 21에서 일반적인 변종 Frontotemporal Lobar 변성 TDP 43 흠도로 연결 됩니다 Nature Genetics. Mar, 2010 | Pubmed ID: 20154673 Neuregulin-1 Beta and Neuregulin-1 Alpha Differentially Affect the Migration and Invasion of Malignant Peripheral Nerve Sheath Tumor Cells Glia. Nov, 2009 | Pubmed ID: 19306381 N F 1의 Schwann 세포 계보 양식 종양은 어떻게? Glia. Nov, 2008 | Pubmed ID: 18803326 C-fos 및 Caspase 3은 신생아 저 산소 증 국 소 빈 혈 다음 Hippocampal 신경 집단간의 차동 활성화 Journal of Neuroscience Research. Apr, 2008 | Pubmed ID: 18030677 BH3 전용 Proapoptotic Bcl-2 가족 구성원 Noxa 및 푸 마 중재 신경 전조 세포 죽음 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2006 | Pubmed ID: 16822983 베타 Neuregulin 모터 신경 Apoptosis에 Neurotrophins 사이 상호 작용 Journal of Neurochemistry. Apr, 2006 | Pubmed ID: 16524373 Neuregulin 성장 요인과 그들의 ErbB 수용 체 Schwannoma Tumorigenesis에 대 한 잠재적인 신호 네트워크를 형성합니다 Journal of Neuropathology and Experimental Neurology. Feb, 2006 | Pubmed ID: 16462207 Neuregulin-1/ErbB 신호 경로의 활성화 인간의 악성 말 초 신경 칼 집 종양에서 종양 약 Schwann 세포의 증식을 촉진합니다 Oncogene. Aug, 2005 | Pubmed ID: 15897877 Neuregulin-1 Astrocytic 인간 신경 세포의 생존을 향상 시킵니다 Glia. Aug, 2005 | Pubmed ID: 15812817 종양 억제기 돌연변이 성장 인자 N F 1 관련 된 말 초 신경의 병 인에서 신호 칼 집 종양: II. Dysregulated 성장 인자 신호의 역할입니다 Journal of Neuropathology and Experimental Neurology. Jan, 2005 | Pubmed ID: 15715079 Neuroglial 셀 섬유 수정 아 데 노 바이러스 벡터를 사용 하 여 향상 된 유전자 배달 Biochemical and Biophysical Research Communications. Mar, 2005 | Pubmed ID: 15708001 당뇨병 변조 유전자 발현의 신경 절의 특정 패턴 Prevertebral에 설정 되 고 Neuroaxonal 영양 실 개발 전에 Paravertebral 교감 신경 Journal of Neuropathology and Experimental Neurology. Nov, 2004 | Pubmed ID: 15581182 종양 억제기 돌연변이 및 성장 인자 N F 1 관련 된 말 초 신경 칼 집 종양의 병 인에서 신호. I. 종양 억제기 돌연변이의 역할입니다 Journal of Neuropathology and Experimental Neurology. Nov, 2004 | Pubmed ID: 15581179 Neuregulin-1beta Neurite 확장 및 교양된 Hippocampal 신경에 있는 Arborization 유도 한다 Molecular and Cellular Neurosciences. Dec, 2004 | Pubmed ID: 15555917 ErbB 막 횡단 티로신 키 니 아 제 수용 체는 좌 골 신경으로 투영 하는 감각 및 모터 뉴런에 의해 표현 됩니다 The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Oct, 2004 | Pubmed ID: 15385576 Neuregulin-1/erbB 신호 경로의 제정 활성화 인간의 주변 Neuroepithelioma 셀 라인의 확산을 촉진합니다 Journal of Neuro-oncology. Feb, 2004 | Pubmed ID: 15015657 Hypertrophic Neuropathies 및 교 증가율 Beta3 Myelinating에서 Overexpressing 유전자 변형 쥐에 악성 말 초 신경 칼 집 종양의 Schwann 세포 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2003 | Pubmed ID: 12917360 Neuregulin-1/ErbB 수용 체 신호 통로의 제정 활성화 종양 약 Schwann 세포 라인의 확산을 위해 필수적 이다 Glia. Aug, 2003 | Pubmed ID: 12838503 Lysophosphatidic 산 Axotomized 좌 골 신경에서 고립 된 성인 Schwann 세포의 증식을 촉진 합니다 Journal of Neuropathology and Experimental Neurology. May, 2003 | Pubmed ID: 12769191 Neuregulin-1 Astrocytic 인간 신경 세포의 마이그레이션 및 운동 성을 향상 시킵니다 The Journal of Biological Chemistry. Jun, 2003 | Pubmed ID: 12600989 Neuregulin-1과 ErbB4 Immunoreactivity Neuritic 플 라크 Alzheimer 질병 뇌와 Alzheimer 질병의 유전자 변형 모델에 연결 됩니다 Journal of Neuropathology and Experimental Neurology. Jan, 2003 | Pubmed ID: 12528817 Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors Dorea P. Jenkins1, Brittany Turner-Ivey1,2, Jody Fromm Longo1, Steven L. Carroll1,2 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Hollings Cancer Center, Medical University of South Carolina JoVE 65740 Recherche en cancérologie Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE Brittany Turner-Ivey1, Jody Fromm Longo2, Dorea P. Jenkins2, Stephen T. Guest3, Steven L. Carroll1,2 1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor JoVE 65430 Recherche en cancérologie 악성 말초 신경 시스 종양 세포에서 Floxed 대립 유전자의 Ex vivo 절제에 의한 종양 발생에서 유전자 기능 정의 Jody Fromm Longo1, Stephanie N. Brosius2,3, Steven L. Carroll1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Department of Pediatrics and Neurology, Perelman School of Medicine of the University of Pennsylvania, 3Division of Child Neurology, Children's Hospital of Philadelphia JoVE 62740 Recherche en cancérologie 대한 인간 루시페라제 태그가 추가된 악성 주변 신경 쉬스 종양 세포 Orthotopic Xenografting 생체내에 테스트 Amy N. Turk1, Stephanie J. Byer1, Kurt R. Zinn2, Steven L. Carroll1,3 1Department of Pathology, University of Alabama at Birmingham - UAB, 2Department of Radiology, University of Alabama at Birmingham - UAB, 3Department of Cell Biology and Neurobiology, University of Alabama at Birmingham - UAB JoVE 2558 Médecine
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors Dorea P. Jenkins1, Brittany Turner-Ivey1,2, Jody Fromm Longo1, Steven L. Carroll1,2 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Hollings Cancer Center, Medical University of South Carolina JoVE 65740 Recherche en cancérologie
Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE Brittany Turner-Ivey1, Jody Fromm Longo2, Dorea P. Jenkins2, Stephen T. Guest3, Steven L. Carroll1,2 1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor JoVE 65430 Recherche en cancérologie
악성 말초 신경 시스 종양 세포에서 Floxed 대립 유전자의 Ex vivo 절제에 의한 종양 발생에서 유전자 기능 정의 Jody Fromm Longo1, Stephanie N. Brosius2,3, Steven L. Carroll1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Department of Pediatrics and Neurology, Perelman School of Medicine of the University of Pennsylvania, 3Division of Child Neurology, Children's Hospital of Philadelphia JoVE 62740 Recherche en cancérologie
대한 인간 루시페라제 태그가 추가된 악성 주변 신경 쉬스 종양 세포 Orthotopic Xenografting 생체내에 테스트 Amy N. Turk1, Stephanie J. Byer1, Kurt R. Zinn2, Steven L. Carroll1,3 1Department of Pathology, University of Alabama at Birmingham - UAB, 2Department of Radiology, University of Alabama at Birmingham - UAB, 3Department of Cell Biology and Neurobiology, University of Alabama at Birmingham - UAB JoVE 2558 Médecine
