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Optimized Venous Thrombosis Assay in a Mouse Cancer Model Using Vascular Clips

January 5th, 2024
1, 1, 1, 2, 2, 3, 1, 4,5, 1,6,7,8
1Renal Section, Department of Medicine, Chobanian and Avedisian School of Medicine, Boston University, 2Vascular Biology Section, Department of Medicine, Chobanian and Avedisian School of Medicine, Boston University, 3Division of Interventional Radiology, Department of Radiology, Chobanian and Avedisian School of Medicine, Boston University, 4Department of Medicine, Whitaker Cardiovascular Institute, Chobanian and Avedisian School of Medicine, Boston University, 5Department of Biochemistry and Cell Biology, Chobanian and Avedisian School of Medicine, Boston University, 6Veterans Affairs Boston Healthcare System, 7Institute of Medical Engineering and Sciences, Massachusetts Institute of Technology, 8Center of Cross-Organ Vascular Pathology, Department of Medicine, Chobanian and Avedisian School of Medicine, Boston University

Summary
Automatic Translation

This article aims to present an optimized method for assessing venous thrombosis in a mouse cancer model, using vascular clips to achieve venous ligation. Optimization minimizes variability in thrombosis-related measurements and enhances relevance to human cancer-associated venous thrombosis.

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