Nanofiber Array Fabrication
Nanofiber Array Fabrication - Related Videos
09:39
Procedure for Fabricating Biofunctional Nanofibers
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Cited by 1 •
2012
An efficient approach for preparing nanofibers decorated with functional groups capable of specifically interacting with proteins is described. The approach first requires the preparation of a polymer functionalized with the appropriate functional group. The functional polymer is fabricated into nanofibers by electrospinning. The effectiveness of the binding of the nanofibers with a protein is studied by confocal microscopy.
13:02
Fabrication of 1-D Photonic Crystal Cavity on a Nanofiber Using Femtosecond Laser-induced Ablation
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Cited by 3 •
2017
We present a protocol for fabricating 1-D photonic crystal cavities on subwavelength diameter silica fibers (optical nanofibers) using femtosecond laser-induced ablation.
08:15
Polymeric Microneedle Array Fabrication by Photolithography
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Cited by 24 •
2015
Here, we present a protocol describing a mold-free fabrication process of the polymeric microneedles by photolithography.
08:21
Fabrication of Periodic Gold Nanocup Arrays Using Colloidal Lithography
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Cited by 1 •
2017
We demonstrate the fabrication of periodic gold nanocup arrays using colloidal lithographic techniques and discuss the importance of nanoplasmonic films.
09:32
Electrospun Nanofiber Scaffolds with Gradations in Fiber Organization
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Cited by 5 •
2015
Here, we present a protocol to fabricate electrospun nanofiber scaffolds with gradated organization of fibers and explore their applications in regulating cell morphology/orientation. Gradients with regard to physical and chemical properties of the nanofiber scaffolds offer a wide variety of applications in the biomedical field.
FAQs
During electrospinning, an electric field draws a polymer solution or melt into thin fibers, and the collecting surface determines how those fibers accumulate. A patterned collector can impose spatial organization, while a rotating collector can promote alignment. Together, the field, polymer feed form, and collector design influence the array’s geometry and its biological or material performance.
These geometric features regulate how cells interact with a scaffold and how the material performs. Alignment can guide cell migration and tissue organization, while spacing affects the available arrangement for attachment. Surface area also contributes to material behavior. Controlling these variables allows researchers to design architectures suited to particular bioengineering objectives.
Adjusting fiber geometry enables scaffolds with tunable biological and mechanical properties. An organized nanoscale architecture can reproduce aspects of fibrous biological environments while providing control over alignment, spacing, and available surface area. This tunability helps researchers match scaffold structure to desired cell attachment, migration, or tissue-organization outcomes.
A typical workflow uses a polymer solution or melt as the fiber-forming material, applies an electric field to draw it into thin fibers, and directs deposition onto a patterned or rotating collector. The collector establishes the spatial arrangement, while the resulting deposit is evaluated through its alignment, spacing, and overall architecture.
Nanofiber arrays can support biosensors, drug delivery systems, wound-care materials, and engineered tissues. Their usefulness comes from the ability to control fiber architecture rather than relying on an unstructured material alone. By adjusting geometry, researchers can create platforms that guide cell interactions or provide material performance suited to the intended application.
The architecture of an array can guide cell attachment, migration, and tissue organization. Alignment and spacing provide structural cues, while the nanoscale fibers create a biomimetic scaffold environment. In bioengineering, these effects are relevant when designing materials intended to support organized tissue development, particularly where cellular arrangement contributes to the desired engineered outcome.