Enteral Continuity

Enteral continuity is the preservation or restoration of an unobstructed gastrointestinal pathway that allows material to pass through the digestive tract. In clinical practice, surgeons establish continuity by joining healthy segments of bowel, often after temporary diversion, resection, or treatment of intestinal injury, while maintaining adequate blood supply and a secure anastomosis. Restored continuity permits enteral nutrition, supports digestion and absorption, and can reduce reliance on ostomies or parenteral feeding when clinically appropriate. Assessing bowel viability, healing, motility, and the risk of leakage or obstruction is essential for safe management and recovery.

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Education

JoVE Science Education - Engineering

Batch and Continuous Bioreactors

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2023

Bioreactors are used to grow organisms in large volumes, thereby enabling the production of mass quantities of the target product. These reactors can be batch reactors, which contain all of the components needed for cell growth, or continuous reactors, which have inlet and outlet ports allowing for the addition of fresh growth media and the removal of cell waste. This video presents batch and continuous reactors and demonstrates the use of bioreactors to grow bacteria in the laboratory.

Research

JoVE Journal - Neuroscience
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In Situ Ca2+ Imaging of the Enteric Nervous System

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Cited by 24 •

2015

The enteric nervous system (ENS) is a network of neurons and glia located in the gut wall that controls intestinal reflexes. This protocol describes methods for recording the activity of enteric neurons and glia in live preparations of ENS using Ca2+ imaging.

Drug Delivery: Enteral Route

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2024

The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs. Drugs in...

Physiology of Enteric Nervous System and Gut Health

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2024

The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...

Enteric Nervous System: Regulation of GI Motor Activity

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2024

The Enteric Nervous System (ENS) plays a pivotal role in regulating gastrointestinal or GI motor activity. This complex network of nerves, deeply embedded within the gut wall, responds to changes in the gut environment and receives input from both the autonomic nervous system and the central nervous system. By doing so, the ENS operates various programs tailored to the body's nutritional status and needs. During periods of fasting, the ENS initiates the migrating myoelectric complex, a program...

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