Learning Deficits

Learning deficits are difficulties acquiring, retaining, or applying new information, and they provide important clues about how cognitive function is organized in the brain. In neuroscience, researchers examine how altered attention, memory formation, synaptic plasticity, or communication among hippocampal and cortical circuits can disrupt learning under specific conditions. Studying these impairments helps distinguish problems with encoding, consolidation, retrieval, or motivation through behavioral tasks and neural measurements. This work supports the evaluation of neurodevelopmental and neurological disorders, informs targeted educational and clinical interventions, and advances understanding of the cellular and circuit mechanisms that enable learning.

Learning Deficits - Related Videos

Research

JoVE Journal - Neuroscience
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Assaying Locomotor, Learning, and Memory Deficits in Drosophila Models of Neurodegeneration

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Cited by 183 •

2011

Behavior assays for measuring locomotor functions, learning, and memory abilities in Drosophila.

Research

JoVE Journal - Neuroscience
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Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

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Cited by 587 •

2011

The Morris Water Maze is a behavioral task to test hippocampal-dependent learning and memory. It has been widely used in the study of neurobiology, neuropharmacology and neurocognitive disorders in rodent models.

Research

JoVE Journal - Behavior
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Detecting Behavioral Deficits in Rats After Traumatic Brain Injury

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Cited by 56 •

2018

The goal of the behavioral tests presented here is to detect functional deficits in rats after traumatic brain injury. Four specific tests are presented that detect deficits in behaviors to reflect the damage to specific brain areas at times extending to one year after injury.

Research

JoVE Journal - Neuroscience
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The Dig Task: A Simple Scent Discrimination Reveals Deficits Following Frontal Brain Damage

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Cited by 14 •

2013

In this protocol, a novel application of scent discrimination is described. The Dig task is a reasonably inexpensive task that can be used to assess frontally-mediated cognition following brain damage.

Research

JoVE Journal - Medicine

Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia

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Cited by 4 •

2017

This study demonstrates the technique to make a minimally invasive and easily reproducible model of spinal cord ischemia in rats. Various degrees of hind limb motor deficit can be produced by controlling the aortic occlusion time.

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