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Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice
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Neuroscience
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JoVE Journal Neuroscience
Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

DOI:
10.3791/2920-v

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07:02 min

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July 20, 2011

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, ,
1Department of Psychiatry, Brain Research Center,University of British Columbia

Chapters

  • 00:05Title
  • 01:27Equipment Preparation
  • 02:03Software Preparation
  • 02:54Day 1: Visible Platform
  • 04:14Day 2-5: Hidden Platform
  • 04:47Day 6: Probe Trial
  • 05:13Data Analysis
  • 05:37VPA’s Effect on Memory Deficits in the APP23 AD Mouse Model
  • 06:28Conclusion

Summary

Automatic Translation

Automatic Translation

The Morris Water Maze is a behavioral task to test hippocampal-dependent learning and memory. It has been widely used in the study of neurobiology, neuropharmacology and neurocognitive disorders in rodent models.

Tags

Morris Water Maze TestLearning DeficitsMemory DeficitsAlzheimer’s Disease Model MiceNeuroscientist Richard G. MorrisSpatial Memory AcquisitionLong-term Spatial MemoryHidden-platform ConditionVisible Platform ConditionOdor Trail InterferenceNeurobiologyNeuropharmacologyRodent Models For Neurocognitive DisordersAlzheimer’s Disease Transgenic Model Mice

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