Pheromone Source Localization

Pheromone source localization is the sensory and neural process by which an organism determines the position of a pheromone emitter, a key problem in chemical communication and spatial behavior. It works by combining pheromone encounters with directional information such as odor concentration, timing, and airflow, allowing sensory circuits to compare signals across space and over time and guide movement toward the source. In neuroscience, researchers use behavioral assays, controlled odor plumes, and neural recordings to link these cues to olfactory processing, orientation decisions, and motor control. This framework clarifies how brains convert intermittent chemical signals into navigation and supports research on social behavior, sensory integration, and biologically inspired navigation systems.

Pheromone Source Localization - Related Videos

Research

JoVE Journal - Behavior

Volatile Sex Pheromone Extraction and Chemoattraction Assay in Caenorhabditis elegans

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Cited by 1 •

2024

This protocol establishes methods for extracting and quantifying responses to the volatile sex pheromone in C. elegans, providing tools to study chemical communication and navigation trajectory.

Research

JoVE Journal - Neuroscience
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Imaging Pheromone Sensing in a Mouse Vomeronasal Acute Tissue Slice Preparation

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Cited by 15 •

2011

In mice, the ability to detect pheromones is principally mediated by the vomeronasal organ (VNO). Here, an acute tissue slice preparation of VNO for performing calcium imaging is described. This physiological approach allows observations of subpopulations and/or individual neurons in a living tissue and is convenient for receptor-ligand identification.

Measuring Physiological Responses of Drosophila Sensory Neurons to Lipid Pheromones Using Live Calcium Imaging

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Cited by 4 •

2016

The forelegs and proboscis of Drosophila contain a rich repertoire of gustatory sensory neurons. Here, we present a method using calcium imaging to measure physiological responses from sensory neurons in the foreleg and proboscis of live flies upon exogenous application of a gustatory pheromone.

Using an Adapted Microfluidic Olfactory Chip for the Imaging of Neuronal Activity in Response to Pheromones in Male C. Elegans Head Neurons

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Cited by 20 •

2017

The use of an adapted "olfactory chip" for the efficient calcium imaging of C. elegans males is described here. Studies of male exposure to glycerol and a pheromone are also shown.

Measuring Local Tissue Strains in Tendons via Open-Source Digital Image Correlation

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Cited by 1 •

2023

This paper describes an open-source digital image correlation algorithm for measuring local 2D tissue strains within tendon explants. The accuracy of the technique has been validated using multiple techniques, and it is available for public use.

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