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Improved Lipofuscin Models and Quantification of Outer Segment Phagocytosis Capacity in Highly Polarized Human Retinal Pigment Epithelial Cultures (Video) | JoVE

Quantifying Retinal Pigment Epithelial Phagocytosis and Lipofuscin Accumulation

Article DOI: 10.3791/65242-v • 02:52 min • April 14th, 2023
April 14th, 2023 •
1, 1, 1,2
1Kellogg Eye Center, University of Michigan, Ann Arbor, 2Cellular and Molecular Biology Program, University of Michigan, Ann Arbor

Tags

Lipofuscin Models Quantification Outer Segment Phagocytosis Human Retinal Pigment Epithelial Cultures Toxicity Aging RPE Physiology In Vitro Models Lipofuscin-like Material Accumulation Highly Differentiated Cultures Photoreceptor Outer Segments Resistance To Lipofuscin Accumulation Toxic Effects Phenotypes Phagocytosis Assay Total Consumptive Capacity
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