Upper Gastrointestinal Surgery
Upper Gastrointestinal Surgery - Related Videos
05:16
Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
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Cited by 2 •
2022
Laparoscopy-endoscopy cooperative surgery is appropriate for the treatment of gastric gastrointestinal stromal tumors less than 5 cm in size. It can achieve the respective advantages of endoscopic and laparoscopic surgeries while avoiding their drawbacks.
06:04
Ex Vivo Intestinal Sacs to Assess Mucosal Permeability in Models of Gastrointestinal Disease
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Cited by 41 •
2016
This protocol describes the use of excised intestinal tissue preparations or "intestinal sacs" as an ex vivo model of intestinal barrier function. This model may be used to assess integrity of both the epithelial barrier and the mucous gel layer at specific intestinal sites in animal models of digestive disease.
08:15
Gastrointestinal Motility Monitor (GIMM)
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Cited by 36 •
2010
Evaluation of colonic motility in the guinea pig distal colon with the Gastrointestinal Motility Monitor (GIMM) is a straightforward and simple to learn approach to quantitatively evaluate propulsive motility in the gastrointestinal tract.
06:02
Isolation of CD 90+ Fibroblast/Myofibroblasts from Human Frozen Gastrointestinal Specimens
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Cited by 17 •
2016
Here, a protocol to isolate and establish primary fibroblast/myofibroblast (MF) cultures from frozen gastric, small intestinal, and colonic tissue-yielding cells with a MF phenotype-is presented. These cells express CD90, α-SMA and vimentin. MFs can be used for a variety of functional assays including enzymatic activity and cytokine production.
06:43
Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
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2026
This video case report demonstrates the unique management of a duodenal gastrointestinal stromal tumor with a rare, understudied, exon 8 KIT mutation. Neoadjuvant therapy resulted in a 30% reduction in tumor size, making the patient a candidate for a robotic-assisted duodenal sleeve resection instead of the more morbid pancreaticoduodenectomy.
FAQs
Anastomosis restores continuity after diseased tissue has been removed or a blockage has been relieved. This reconstruction helps reconnect the digestive tract so that nutrition can continue through the esophagus, stomach, and duodenum. Preserving continuity and organ function therefore becomes a central surgical objective, particularly when treatment requires tissue removal.
The principal difference is how surgeons access the affected structures. Open operations use a conventional surgical access route, whereas minimally invasive approaches use techniques such as laparoscopy. The overview emphasizes that minimally invasive access aims to reduce tissue trauma and shorten recovery, while the selected approach remains part of planning for complex disease and emergencies.
The operative objective follows the problem being treated. Cancer may require removal of diseased tissue, bleeding may require control of hemorrhage, and obstruction may require relief of blockage. Severe reflux represents another disorder that may need operative treatment when medical therapy is insufficient. These goals determine whether removal, control, decompression, or reconstruction is emphasized.
A procedure generally begins with access to the affected region, followed by the intervention required for the underlying disorder. Surgeons may remove diseased tissue, control bleeding, or relieve an obstruction. When anatomy has been interrupted, they reconstruct the digestive tract, often with anastomosis, while perioperative care supports recovery and preservation of function.
Surgery may be considered when a disorder does not respond adequately to medical therapy, when cancer requires operative treatment, or when an emergency such as significant bleeding or obstruction demands rapid correction. The approach also applies to complex conditions in which restoring digestive continuity or protecting nutrition and organ function cannot be achieved through medical management alone.
These advances support different parts of treatment. Laparoscopy can provide minimally invasive surgical access, while endoscopy contributes to the broader management of upper gastrointestinal disorders. Perioperative care supports patients around the operation. Together, these developments aim to reduce tissue trauma, shorten recovery, and improve long-term outcomes without changing the need to match treatment to the disorder.