Vitamin Formulation

Vitamin formulation is the design of vitamin-containing medicines and supplements to deliver a stable, effective, and usable dose. It combines the selected vitamin with suitable excipients and dosage forms, such as tablets, capsules, liquids, or powders, while accounting for factors including solubility, chemical stability, absorption, and compatibility among ingredients. In medicine, formulation decisions influence shelf life, dosing accuracy, patient adherence, and bioavailability. Careful development and quality testing help ensure that products provide consistent vitamin content and perform as intended, supporting prevention or treatment of deficiency and enabling reliable use across different patient needs.

Vitamin Formulation - Related Videos

Research

JoVE Journal - Biochemistry
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Formulation of Vitamin A Tracer Doses for Administration to Human Subjects using Retinol Isotope Dilution Technique

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2026

The preparation of stable isotope-labeled vitamin A, necessary for the retinol isotope dilution technique, needs to conform to food safety standards. The protocol shows dosage preparation in vegetable oil at concentrations that will be suitable for the chosen delivery system and the applied analytical platform.

PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS

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Cited by 211 •

2013

We describe the production and characterization of nanoparticles and microparticles composed of poly(lactic-co-glycolic acid) using vitamin E-TPGS as an emulsifier. By varying formulation parameters such as the concentration of emulsifier, it is possible to produce nanoparticles with mean diameters ranging from 220 nm to 1.98 µm.

Education

JoVE Core - Anatomy and Physiology

Vitamins

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2024

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...

Formulations for Freeze-drying of Bacteria and Their Influence on Cell Survival

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Cited by 22 •

2013

Freeze-drying is often an easy and convenient way to obtain dry products of viable bacterial cells. An issue of the process is cell survival. We detail here a procedure to investigate how cell survival during freeze-drying is influenced by the properties of the formulation used.

Evaluating the Effect of a Synbiotic Formulation on Alzheimer’s Disease Pathology in Drosophila

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2025

Take a transgenic Drosophila.The brain of the Drosophila expresses the human amyloid peptide protein or APP and a cleaving enzyme.The enzyme cleaves APP, enabling the formation of beta-amyloid plaque, which leads toAlzheimer's disease or AD pathology in Drosophila.Feed the Drosophila AD model a diet containing a synbiotic formulation.The formulation contains a combination of three bioactive probiotic bacteria and a prebiotic.Inside the fly's gut, the prebiotic supports the growth and survival...

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