Adam J. Adler Arthritis and Clinical Immunology Oklahoma Medical Research Foundation Biography Publications Institution JoVE Articles Adam J. Adler has not added a biography. If you are Adam J. Adler and would like to personalize this page please email our Author Liaison for assistance. Publications Variants at Multiple Loci Implicated in Both Innate and Adaptive Immune Responses Are Associated with Sjögren's Syndrome Nature Genetics. Nov, 2013 | Pubmed ID: 24097067 Betting on Improved Cancer Immunotherapy by Doubling Down on CD134 and CD137 Co-stimulation Oncoimmunology. Jan, 2013 | Pubmed ID: 23482891 CD134/CD137 Dual Costimulation-elicited IFN-γ Maximizes Effector T-cell Function but Limits Treg Expansion Immunology and Cell Biology. Feb, 2013 | Pubmed ID: 23295363 Lymphatic Endothelial Cells Induce Tolerance Via PD-L1 and Lack of Costimulation Leading to High-level PD-1 Expression on CD8 T Cells Blood. Dec, 2012 | Pubmed ID: 22993390 Two Independent Functional Risk Haplotypes in TNIP1 Are Associated with Systemic Lupus Erythematosus Arthritis and Rheumatism. Jul, 2012 | Pubmed ID: 22833143 Presensitizing with a Toll-like Receptor 3 Ligand Impairs CD8 T-cell Effector Differentiation and IL-33 Responsiveness Proceedings of the National Academy of Sciences of the United States of America. Jun, 2012 | Pubmed ID: 22689946 Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 As Susceptibility Loci for Systemic Lupus Erythematosus in a Large-scale Multiracial Replication Study American Journal of Human Genetics. Apr, 2012 | Pubmed ID: 22464253 CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cells to Program Cytotoxic Th1 Differentiation Journal of Immunology (Baltimore, Md. : 1950). Oct, 2011 | Pubmed ID: 21880986 Tc17 CD8 T Cells: Functional Plasticity and Subset Diversity Journal of Immunology (Baltimore, Md. : 1950). Dec, 2009 | Pubmed ID: 19917680 Blood Feeding by the Rocky Mountain Spotted Fever Vector, Dermacentor Andersoni, Induces Interleukin-4 Expression by Cognate Antigen Responding CD4+ T Cells Parasites & Vectors. 2009 | Pubmed ID: 19814808 The E3 Ubiquitin Ligase Cbl-b Regulates Expansion but Not Functional Activity of Self-reactive CD4 T Cells Journal of Immunology (Baltimore, Md. : 1950). Oct, 2009 | Pubmed ID: 19801520 In Vitro and in Vivo Differentiated Effector CD8 T Cells Display Divergent Histone Acetylation Patterns Within the Ifng Locus Immunology Letters. Feb, 2009 | Pubmed ID: 19195486 The IKK-neutralizing Compound Bay11 Kills Supereffector CD8 T Cells by Altering Caspase-dependent Activation-induced Cell Death Journal of Leukocyte Biology. Jan, 2009 | Pubmed ID: 18923104 Self-antigen Prevents CD8 T Cell Effector Differentiation by CD134 and CD137 Dual Costimulation Journal of Immunology (Baltimore, Md. : 1950). Dec, 2008 | Pubmed ID: 19017962 Histone Acetylation at the Ifng Promoter in Tolerized CD4 Cells is Associated with Increased IFN-gamma Expression During Subsequent Immunization to the Same Antigen Journal of Immunology (Baltimore, Md. : 1950). Nov, 2007 | Pubmed ID: 17947638 Steady State Dendritic Cells Present Parenchymal Self-antigen and Contribute To, but Are Not Essential For, Tolerization of Naive and Th1 Effector CD4 Cells Journal of Immunology (Baltimore, Md. : 1950). Aug, 2007 | Pubmed ID: 17641018 Mechanisms of T Cell Tolerance and Suppression in Cancer Mediated by Tumor-associated Antigens and Hormones Current Cancer Drug Targets. Feb, 2007 | Pubmed ID: 17305474 Dendritic Cells Program Non-immunogenic Prostate-specific T Cell Responses Beginning at Early Stages of Prostate Tumorigenesis The Prostate. Apr, 2007 | Pubmed ID: 17221844 Cutting Edge: Paracrine, but Not Autocrine, IL-2 Signaling is Sustained During Early Antiviral CD4 T Cell Response Journal of Immunology (Baltimore, Md. : 1950). Oct, 2006 | Pubmed ID: 16982857 Evaluation of the Genetic Association of the PTPN22 R620W Polymorphism in Familial and Sporadic Systemic Lupus Erythematosus Arthritis and Rheumatism. Aug, 2006 | Pubmed ID: 16868974 T-bet Down-modulation in Tolerized Th1 Effector CD4 Cells Confers a TCR-distal Signaling Defect That Selectively Impairs IFN-gamma Expression Journal of Immunology (Baltimore, Md. : 1950). Jan, 2006 | Pubmed ID: 16393991 Peripheral Tolerization of Effector and Memory T Cells: Implications for Autoimmunity and Tumor-Immunity Current Immunology Reviews. Jan, 2005 | Pubmed ID: 20411047 Androgen Ablation Mitigates Tolerance to a Prostate/prostate Cancer-restricted Antigen Cancer Cell. Mar, 2005 | Pubmed ID: 15766662 Glycoprotein 96 Can Chaperone Both MHC Class I- and Class II-restricted Epitopes for in Vivo Presentation, but Selectively Primes CD8+ T Cell Effector Function Journal of Immunology (Baltimore, Md. : 1950). May, 2004 | Pubmed ID: 15128793 In Vivo Cyclophosphamide and IL-2 Treatment Impedes Self-antigen-induced Effector CD4 Cell Tolerization: Implications for Adoptive Immunotherapy Journal of Immunology (Baltimore, Md. : 1950). May, 2004 | Pubmed ID: 15100273 Effector CD4 Cell Tolerization is Mediated Through Functional Inactivation and Involves Preferential Impairment of TNF-alpha and IFN-gamma Expression Potentials Cellular Immunology. Aug, 2003 | Pubmed ID: 14609577 CD4+ T Cells Pass Through an Effector Phase During the Process of in Vivo Tolerance Induction Journal of Immunology (Baltimore, Md. : 1950). Apr, 2003 | Pubmed ID: 12682221 Effector CD4 Cells Are Tolerized Upon Exposure to Parenchymal Self-antigen Journal of Immunology (Baltimore, Md. : 1950). Oct, 2002 | Pubmed ID: 12244153 CD4 Cell Priming and Tolerization Are Differentially Programmed by APCs Upon Initial Engagement Journal of Immunology (Baltimore, Md. : 1950). Jun, 2002 | Pubmed ID: 12023353 Infinium Assay for Large-scale SNP Genotyping Applications Adam J. Adler1, Graham B. Wiley1, Patrick M. Gaffney1 1Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation JoVE 50683 Biologia
Infinium Assay for Large-scale SNP Genotyping Applications Adam J. Adler1, Graham B. Wiley1, Patrick M. Gaffney1 1Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation JoVE 50683 Biologia