Alberto Anel Department of Biochemistry University of Zaragoza Biography Publications Institution JoVE Articles Alberto Anel has not added a biography. If you are Alberto Anel and would like to personalize this page please email our Author Liaison for assistance. Publications Study of the Bcl-2 Interactome by BiFC Reveals Differences in the Activation Mechanism of Bax and Bak Cells. Mar, 2023 | Pubmed ID: 36899936 DR5 Up-Regulation Induced by Dichloroacetate Sensitizes Tumor Cells to Lipid Nanoparticles Decorated with TRAIL Journal of Clinical Medicine. Jan, 2023 | Pubmed ID: 36675536 Ecto-calreticulin Expression in Multiple Myeloma Correlates with a Failed Anti-tumoral Immune Response and Bad Prognosis Oncoimmunology. 2022 | Pubmed ID: 36338146 PT-112 Induces Mitochondrial Stress and Immunogenic Cell Death, Targeting Tumor Cells with Mitochondrial Deficiencies Cancers. Aug, 2022 | Pubmed ID: 36010843 Conjugation of the 9-kDa Isoform of Granulysin with Liposomes Potentiates Its Cytotoxicity International Journal of Molecular Sciences. Aug, 2022 | Pubmed ID: 35955839 Preclinical Studies of Granulysin-Based Anti-MUC1-Tn Immunotoxins As a New Antitumoral Treatment Biomedicines. May, 2022 | Pubmed ID: 35740244 Evaluation in a Cytokine Storm Model In Vivo of the Safety and Efficacy of Intravenous Administration of PRS CK STORM (Standardized Conditioned Medium Obtained by Coculture of Monocytes and Mesenchymal Stromal Cells) Biomedicines. May, 2022 | Pubmed ID: 35625831 Cytokine Profile and Anti-Inflammatory Activity of a Standardized Conditioned Medium Obtained by Coculture of Monocytes and Mesenchymal Stromal Cells (PRS CK STORM) Biomolecules. Mar, 2022 | Pubmed ID: 35454123 The Metabolism of Cells Regulates Their Sensitivity to NK Cells Depending on P53 Status Scientific Reports. Feb, 2022 | Pubmed ID: 35217717 Harnessing the Potential of NK Cell-Based Immunotherapies Against Multiple Myeloma Cells. Jan, 2022 | Pubmed ID: 35159200 Metformin Sensitizes Leukemic Cells to Cytotoxic Lymphocytes by Increasing Expression of Intercellular Adhesion Molecule-1 (ICAM-1) Scientific Reports. Jan, 2022 | Pubmed ID: 35079096 Antibody-Based Immunotoxins for Colorectal Cancer Therapy Biomedicines. Nov, 2021 | Pubmed ID: 34829955 Future Prospects for Mitosis-targeted Antitumor Therapies Biochemical Pharmacology. Aug, 2021 | Pubmed ID: 34129859 In Vivo Potential of Recombinant Granulysin Against Human Melanoma Cancer Treatment and Research Communications. 2021 | Pubmed ID: 33770663 Immunologic Evaluation and Genetic Defects of Apoptosis in Patients with Autoimmune Lymphoproliferative Syndrome (ALPS) Critical Reviews in Clinical Laboratory Sciences. Jun, 2021 | Pubmed ID: 33356695 Expanded NK Cells from Umbilical Cord Blood and Adult Peripheral Blood Combined with Daratumumab Are Effective Against Tumor Cells from Multiple Myeloma Patients Oncoimmunology. Dec, 2020 | Pubmed ID: 33457074 Expanded and Activated Allogeneic NK Cells Are Cytotoxic Against B-chronic Lymphocytic Leukemia (B-CLL) Cells with Sporadic Cases of Resistance Scientific Reports. Nov, 2020 | Pubmed ID: 33173077 Production of a Granulysin-Based, Tn-Targeted Cytolytic Immunotoxin Using Pulsed Electric Field Technology International Journal of Molecular Sciences. Aug, 2020 | Pubmed ID: 32859066 Editorial: The Natural Killer Cell Interactome in the Tumor Microenvironment: Basic Concepts and Clinical Application Frontiers in Immunology. 2020 | Pubmed ID: 32508819 Novel Forms of Immunomodulation for Cancer Therapy Trends in Cancer. Jun, 2020 | Pubmed ID: 32460005 Response: Commentary: Immunogenic Cell Death and Immunotherapy of Multiple Myeloma Frontiers in Cell and Developmental Biology. 2019 | Pubmed ID: 31828071 Anti-tumoral Potential of a Human Granulysin-based, CEA-targeted Cytolytic Immunotoxin Oncoimmunology. 2019 | Pubmed ID: 31646080 Mutations in the Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells Cancers. Jul, 2019 | Pubmed ID: 31330915 Immunogenic Cell Death and Immunotherapy of Multiple Myeloma Frontiers in Cell and Developmental Biology. 2019 | Pubmed ID: 31041312 Importance of TRAIL Molecular Anatomy in Receptor Oligomerization and Signaling. Implications for Cancer Therapy Cancers. Mar, 2019 | Pubmed ID: 30934872 Role of Exosomes in the Regulation of T-cell Mediated Immune Responses and in Autoimmune Disease Cells. Feb, 2019 | Pubmed ID: 30759880 Expansion of Allogeneic NK Cells with Efficient Antibody-dependent Cell Cytotoxicity Against Multiple Tumors Theranostics. 2018 | Pubmed ID: 30083264 Lipid Nanoparticles Decorated with TNF-Related Aptosis-Inducing Ligand (TRAIL) Are More Cytotoxic Than Soluble Recombinant TRAIL in Sarcoma International Journal of Molecular Sciences. May, 2018 | Pubmed ID: 29757258 Mitochondrial Complex I Activity Signals Antioxidant Response Through ERK5 Scientific Reports. May, 2018 | Pubmed ID: 29743487 Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells Frontiers in Immunology. 2016 | Pubmed ID: 27833611 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 How Do Cytotoxic Lymphocytes Kill Cancer Cells? Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2015 | Pubmed ID: 26567364 Potential of Recombinant Granulysin Against Human Tumors Oncoimmunology. Sep, 2015 | Pubmed ID: 26405603 Second Meeting of the Spanish Immunotherapy Group GEIT (Grupo Español De Inmunoterapia), January 16, 2015, in Zaragoza, Spain Cancer Immunology, Immunotherapy : CII. Aug, 2015 | Pubmed ID: 26076665 Human NK Cells Activated by EBV(+) Lymphoblastoid Cells Overcome Anti-apoptotic Mechanisms of Drug Resistance in Haematological Cancer Cells Oncoimmunology. Mar, 2015 | Pubmed ID: 25949911 MHC-I Modulation Due to Changes in Tumor Cell Metabolism Regulates Tumor Sensitivity to CTL and NK Cells Oncoimmunology. Jan, 2015 | Pubmed ID: 25949869 Liposome-bound TRAIL Induces Superior DR5 Clustering and Enhanced DISC Recruitment in Histiocytic Lymphoma U937 Cells Leukemia Research. Jun, 2015 | Pubmed ID: 25882551 IFNα Signaling Through PKC-θ is Essential for Antitumor NK Cell Function Oncoimmunology. 2014 | Pubmed ID: 25960930 All-trans Retinoic Acid (ATRA) Induces MiR-23a Expression, Decreases CTSC Expression and Granzyme B Activity Leading to Impaired NK Cell Cytotoxicity The International Journal of Biochemistry & Cell Biology. Apr, 2014 | Pubmed ID: 24440757 Granulysin Induces Apoptotic Cell Death and Cleavage of the Autophagy Regulator Atg5 in Human Hematological Tumors Biochemical Pharmacology. Feb, 2014 | Pubmed ID: 24269628 Protein Kinase C-theta is Required for NK Cell Activation and in Vivo Control of Tumor Progression Journal of Immunology (Baltimore, Md. : 1950). Feb, 2009 | Pubmed ID: 19201850 Apo2L/TRAIL and Immune Regulation Frontiers in Bioscience : a Journal and Virtual Library. Jan, 2007 | Pubmed ID: 17127445 Transmitochondrial Cybrid Generation Using Cancer Cell Lines (Video) | JoVE Ruth Soler-Agesta1, Joaquín Marco-Brualla1, Patricio Fernández-Silva1,2, Pilar Mozas1,3, Alberto Anel1, Raquel Moreno Loshuertos1,2 1Department of Biochemistry, University of Zaragoza, 2Institute for Biocomputation and Physics of Complex Systems, University of Zaragoza, 3Sequencing and Functional Genomics Unit, University of Zaragoza-IACS JoVE 65186 Ricerca sul cancro
Transmitochondrial Cybrid Generation Using Cancer Cell Lines (Video) | JoVE Ruth Soler-Agesta1, Joaquín Marco-Brualla1, Patricio Fernández-Silva1,2, Pilar Mozas1,3, Alberto Anel1, Raquel Moreno Loshuertos1,2 1Department of Biochemistry, University of Zaragoza, 2Institute for Biocomputation and Physics of Complex Systems, University of Zaragoza, 3Sequencing and Functional Genomics Unit, University of Zaragoza-IACS JoVE 65186 Ricerca sul cancro
