Avi Gnatt Department of Pharmacology & Experimental Therapeutics University of Maryland School of Medicine Biography Publications Institution JoVE Articles Avi Gnatt has not added a biography. If you are Avi Gnatt and would like to personalize this page please email our Author Liaison for assistance. Publications Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides PLoS Pathogens. 2012 | Pubmed ID: 23166498 Regulation of Mammalian Transcription by Gdown1 Through a Novel Steric Crosstalk Revealed by Cryo-EM The EMBO Journal. Aug, 2012 | Pubmed ID: 22850672 Efficient Reconstitution of Transcription Elongation Complexes for Single-molecule Studies of Eukaryotic RNA Polymerase II Transcription. May-Jun, 2012 | Pubmed ID: 22771949 Regolazione Trascrizionale Di Pol II Che Coinvolge Mediatore E Interazioni Competitive Di Gdown1 E TFIIF Con Pol II Molecular Cell. Jan, 2012 | Pubmed ID: 22244332 Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes Molecular Cell. Jan, 2012 | Pubmed ID: 22244331 Regulation of RUNX2 Transcription Factor-DNA Interactions and Cell Proliferation by Vitamin D3 (cholecalciferol) Prohormone Activity Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Apr, 2012 | Pubmed ID: 22189971 Differential Blocking Effects of the Acetaldehyde-derived DNA Lesion N2-ethyl-2'-deoxyguanosine on Transcription by Multisubunit and Single Subunit RNA Polymerases The Journal of Biological Chemistry. Oct, 2008 | Pubmed ID: 18669632 Knockdown of TFIIS by RNA Silencing Inhibits Cancer Cell Proliferation and Induces Apoptosis BMC Cancer. 2008 | Pubmed ID: 18474089 A Mediator-responsive Form of Metazoan RNA Polymerase II Proceedings of the National Academy of Sciences of the United States of America. Jun, 2006 | Pubmed ID: 16769904 Fcp1 Directly Recognizes the C-terminal Domain (CTD) and Interacts with a Site on RNA Polymerase II Distinct from the CTD Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16301539 Cancer Outcomes at the Hufeland (complementary/alternative Medicine) Klinik: a Best-case Series Review Integrative Cancer Therapies. Jun, 2005 | Pubmed ID: 15911928 Elongation by RNA Polymerase II: Structure-function Relationship Biochimica Et Biophysica Acta. Sep, 2002 | Pubmed ID: 12213651 Structural Basis of Transcription: an RNA Polymerase II Elongation Complex at 3.3 A Resolution Science (New York, N.Y.). Jun, 2001 | Pubmed ID: 11313499 Architecture of RNA Polymerase II and Implications for the Transcription Mechanism Science (New York, N.Y.). Apr, 2000 | Pubmed ID: 10784442 Yeast RNA Polymerase II at 5 A Resolution Cell. Sep, 1999 | Pubmed ID: 10499797 Electron Crystal Structure of an RNA Polymerase II Transcription Elongation Complex Cell. Sep, 1999 | Pubmed ID: 10499796 Repeated Tertiary Fold of RNA Polymerase II and Implications for DNA Binding Journal of Molecular Biology. Jul, 1998 | Pubmed ID: 9665838 Formation and Crystallization of Yeast RNA Polymerase II Elongation Complexes The Journal of Biological Chemistry. Dec, 1997 | Pubmed ID: 9388221 Evidence for a Mediator Cycle at the Initiation of Transcription Proceedings of the National Academy of Sciences of the United States of America. Jun, 1997 | Pubmed ID: 9177171 Site-directed Mutagenesis of Active Site Residues Reveals Plasticity of Human Butyrylcholinesterase in Substrate and Inhibitor Interactions Journal of Neurochemistry. Feb, 1994 | Pubmed ID: 8294937 Testicular Amplification and Impaired Transmission of Human Butyrylcholinesterase CDNA in Transgenic Mice Human Reproduction (Oxford, England). Feb, 1994 | Pubmed ID: 8027285 Structure-function Relationship Studies in Human Cholinesterases Reveal Genomic Origins for Individual Variations in Cholinergic Drug Responses Progress in Neuro-psychopharmacology & Biological Psychiatry. Nov, 1993 | Pubmed ID: 8278601 Chimeric Human Cholinesterase. Identification of Interaction Sites Responsible for Recognition of Acetyl- or Butyrylcholinesterase-specific Ligands Journal of Molecular Biology. Nov, 1993 | Pubmed ID: 8230213 Excavations into the Active-site Gorge of Cholinesterases Trends in Biochemical Sciences. Sep, 1992 | Pubmed ID: 1412713 Intramolecular Relationships in Cholinesterases Revealed by Oocyte Expression of Site-directed and Natural Variants of Human BCHE The EMBO Journal. Apr, 1992 | Pubmed ID: 1373381 Human Acetylcholinesterase and Butyrylcholinesterase Are Encoded by Two Distinct Genes Cellular and Molecular Neurobiology. Feb, 1991 | Pubmed ID: 2013062 Expression of Alternatively Terminated Unusual Human Butyrylcholinesterase Messenger RNA Transcripts, Mapping to Chromosome 3q26-ter, in Nervous System Tumors Cancer Research. Apr, 1990 | Pubmed ID: 2317787 Molecular Cloning and Construction of the Coding Region for Human Acetylcholinesterase Reveals a G + C-rich Attenuating Structure Proceedings of the National Academy of Sciences of the United States of America. Dec, 1990 | Pubmed ID: 2263619 Anionic Site Interactions in Human Butyrylcholinesterase Disrupted by Two Single Point Mutations The Journal of Biological Chemistry. Dec, 1990 | Pubmed ID: 2249982 Aspartate-70 to Glycine Substitution Confers Resistance to Naturally Occurring and Synthetic Anionic-site Ligands on In-ovo Produced Human Butyrylcholinesterase Journal of Neuroscience Research. Dec, 1990 | Pubmed ID: 2079709 Molecular Biological Search for Human Genes Encoding Cholinesterases Molecular Neurobiology. Spring-Summer, 1987 | Pubmed ID: 3077058 Isolation and Characterization of Full-length CDNA Clones Coding for Cholinesterase from Fetal Human Tissues Proceedings of the National Academy of Sciences of the United States of America. Jun, 1987 | Pubmed ID: 3035536 Molecular Cloning of Human Cholinesterase Genes: Potential Applications in Neurotoxicology Progress in Clinical and Biological Research. 1987 | Pubmed ID: 2963345 Use of Synthetic Oligodeoxynucleotide Probes for the Isolation of a Human Cholinesterase CDNA Clone Journal of Neuroscience Research. 1986 | Pubmed ID: 3755763 Un quantitativo test per studiare proteine: DNA interazioni, Discover trascrizionali regolatori dell'espressione genica, e identificare nuovi agenti anti-tumorali Karen F. Underwood1, Maria T. Mochin1, Jessica L. Brusgard2, Moran Choe3, Avi Gnatt4, Antonino Passaniti3,5 1Greenebaum Cancer Center, University of Maryland School of Medicine, 2Program in Molecular Medicine, University of Maryland School of Medicine, 3Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, 4Department of Pharmacology & Experimental Therapeutics, University of Maryland School of Medicine, 5Department of Pathology and Biochemistry & Molecular Biology, University of Maryland School of Medicine JoVE 50512 Biologia
Un quantitativo test per studiare proteine: DNA interazioni, Discover trascrizionali regolatori dell'espressione genica, e identificare nuovi agenti anti-tumorali Karen F. Underwood1, Maria T. Mochin1, Jessica L. Brusgard2, Moran Choe3, Avi Gnatt4, Antonino Passaniti3,5 1Greenebaum Cancer Center, University of Maryland School of Medicine, 2Program in Molecular Medicine, University of Maryland School of Medicine, 3Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, 4Department of Pharmacology & Experimental Therapeutics, University of Maryland School of Medicine, 5Department of Pathology and Biochemistry & Molecular Biology, University of Maryland School of Medicine JoVE 50512 Biologia