Charles Steenbergen Department of Pathology, Department of Cardiology Johns Hopkins University Biography Publications Institution JoVE Articles Charles Steenbergen has not added a biography. If you are Charles Steenbergen and would like to personalize this page please email our Author Liaison for assistance. Publications Genetic Testing Improves Identification of Transthyretin Amyloid (ATTR) Subtype in Cardiac Amyloidosis Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. Jun, 2017 | Pubmed ID: 28494620 Adenosine A1 Receptor Activation Increases Myocardial Protein S-nitrosothiols and Elicits Protection from Ischemia-reperfusion Injury in Male and Female Hearts PloS One. 2017 | Pubmed ID: 28493997 MiR-181b Regulates Vascular Stiffness Age Dependently in Part by Regulating TGF-β Signaling PloS One. 2017 | Pubmed ID: 28323879 Divergent Effects of MiR-181 Family Members on Myocardial Function Through Protective Cytosolic and Detrimental Mitochondrial MicroRNA Targets Journal of the American Heart Association. Feb, 2017 | Pubmed ID: 28242633 Exosomal MicroRNA-15a Transfer from the Pancreas Augments Diabetic Complications by Inducing Oxidative Stress Antioxidants & Redox Signaling. Nov, 2017 | Pubmed ID: 28173719 Characterization of the Sex-dependent Myocardial S-nitrosothiol Proteome American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2016 | Pubmed ID: 26702143 Hyaluronic Acid-serum Hydrogels Rapidly Restore Metabolism of Encapsulated Stem Cells and Promote Engraftment Biomaterials. Dec, 2015 | Pubmed ID: 26378976 ErbB2 Overexpression Upregulates Antioxidant Enzymes, Reduces Basal Levels of Reactive Oxygen Species, and Protects Against Doxorubicin Cardiotoxicity American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2015 | Pubmed ID: 26254336 The NHLBI-sponsored Consortium for PreclinicAl AssESsment of CARdioprotective Therapies (CAESAR): a New Paradigm for Rigorous, Accurate, and Reproducible Evaluation of Putative Infarct-sparing Interventions in Mice, Rabbits, and Pigs Circulation Research. Feb, 2015 | Pubmed ID: 25499773 Glyceraldehyde-3-phosphate Dehydrogenase Acts As a Mitochondrial Trans-S-nitrosylase in the Heart PloS One. 2014 | Pubmed ID: 25347796 MiR-181c Regulates the Mitochondrial Genome, Bioenergetics, and Propensity for Heart Failure in Vivo PloS One. 2014 | Pubmed ID: 24810628 Pivotal Role of MTORC2 and Involvement of Ribosomal Protein S6 in Cardioprotective Signaling Circulation Research. Apr, 2014 | Pubmed ID: 24557881 S-nitrosylation of TRIM72 at Cysteine 144 is Critical for Protection Against Oxidation-induced Protein Degradation and Cell Death Journal of Molecular and Cellular Cardiology. Apr, 2014 | Pubmed ID: 24487118 Strengthening the Skin with Topical Delivery of Keratinocyte Growth Factor-1 Using a Novel DNA Plasmid Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2014 | Pubmed ID: 24434934 Hydrogen Sulfide [corrected] Increases Survival During Sepsis: Protective Effect of CHOP Inhibition Journal of Immunology (Baltimore, Md. : 1950). Feb, 2014 | Pubmed ID: 24403532 Skeletal Muscle ATP Kinetics Are Impaired in Frail Mice Age (Dordrecht, Netherlands). Feb, 2014 | Pubmed ID: 23695949 Creatine Kinase-overexpression Improves Myocardial Energetics, Contractile Dysfunction and Survival in Murine Doxorubicin Cardiotoxicity PloS One. 2013 | Pubmed ID: 24098344 Cardioprotection and Myocardial Reperfusion: Pitfalls to Clinical Application Circulation Research. Aug, 2013 | Pubmed ID: 23908333 Integration and Regression of Implanted Engineered Human Vascular Networks During Deep Wound Healing Stem Cells Translational Medicine. Apr, 2013 | Pubmed ID: 23486832 Creatine Kinase Overexpression Improves ATP Kinetics and Contractile Function in Postischemic Myocardium American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2012 | Pubmed ID: 22886411 Measurement of S-nitrosylation Occupancy in the Myocardium with Cysteine-reactive Tandem Mass Tags: Short Communication Circulation Research. Oct, 2012 | Pubmed ID: 22865876 A Composite Polymer Nanoparticle Overcomes Multidrug Resistance and Ameliorates Doxorubicin-associated Cardiomyopathy Oncotarget. Jun, 2012 | Pubmed ID: 22791660 Nuclear MiRNA Regulates the Mitochondrial Genome in the Heart Circulation Research. Jun, 2012 | Pubmed ID: 22518031 Endothelial Expression of Hypoxia-inducible Factor 1 Protects the Murine Heart and Aorta from Pressure Overload by Suppression of TGF-β Signaling Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012 | Pubmed ID: 22403061 Creatine Kinase-mediated Improvement of Function in Failing Mouse Hearts Provides Causal Evidence the Failing Heart is Energy Starved The Journal of Clinical Investigation. Jan, 2012 | Pubmed ID: 22201686 Mitochondrial Permeability Transition Pore and Calcium Handling Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22057571 Mitochondrial Adenine Nucleotide Transport and Cardioprotection Journal of Molecular and Cellular Cardiology. Feb, 2012 | Pubmed ID: 21945520 Impact of Scar, Viable Myocardium, and Epicardial Fat on Substrate Identification of Ventricular Tachycardia in a Case with Nonischemic Cardiomyopathy Pacing and Clinical Electrophysiology : PACE. Dec, 2012 | Pubmed ID: 21883316 Dextran Hydrogel Scaffolds Enhance Angiogenic Responses and Promote Complete Skin Regeneration During Burn Wound Healing Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22171002 Cysteine 203 of Cyclophilin D is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore The Journal of Biological Chemistry. Nov, 2011 | Pubmed ID: 21930693 Controlled Activation of Morphogenesis to Generate a Functional Human Microvasculature in a Synthetic Matrix Blood. Jul, 2011 | Pubmed ID: 21527523 Ischemic Preconditioning Attenuates Mitochondrial Localization of PTEN Induced by Ischemia-reperfusion American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2011 | Pubmed ID: 21421815 Mechanism of Cardioprotection: What Can We Learn from Females? Pediatric Cardiology. Mar, 2011 | Pubmed ID: 21279340 Functional Neovascularization of Biodegradable Dextran Hydrogels with Multiple Angiogenic Growth Factors Biomaterials. Jan, 2011 | Pubmed ID: 20870284 VAMP-1, VAMP-2, and Syntaxin-4 Regulate ANP Release from Cardiac Myocytes Journal of Molecular and Cellular Cardiology. Nov, 2010 | Pubmed ID: 20801128 Sex Differences in the Phosphorylation of Mitochondrial Proteins Result in Reduced Production of Reactive Oxygen Species and Cardioprotection in Females Circulation Research. Jun, 2010 | Pubmed ID: 20413785 Adenoviral Transfer of HIF-1alpha Enhances Vascular Responses to Critical Limb Ischemia in Diabetic Mice Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19841279 Engraftment, Differentiation, and Functional Benefits of Autologous Cardiosphere-derived Cells in Porcine Ischemic Cardiomyopathy Circulation. Sep, 2009 | Pubmed ID: 19738142 Autologous Mesenchymal Stem Cells Produce Reverse Remodelling in Chronic Ischaemic Cardiomyopathy European Heart Journal. Nov, 2009 | Pubmed ID: 19586959 Estrogen Receptor-beta Activation Results in S-nitrosylation of Proteins Involved in Cardioprotection Circulation. Jul, 2009 | Pubmed ID: 19581491 Cardioprotection and Altered Mitochondrial Adenine Nucleotide Transport Basic Research in Cardiology. Mar, 2009 | Pubmed ID: 19242642 Glycogen Synthase Kinase 3 Inhibition Slows Mitochondrial Adenine Nucleotide Transport and Regulates Voltage-dependent Anion Channel Phosphorylation Circulation Research. Oct, 2008 | Pubmed ID: 18802025 In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge Oliver A. Kent1, Charles Steenbergen2, Samarjit Das2 1Princess Margaret Cancer Centre, University of Toronto, 2Department of Pathology, Department of Cardiology, Johns Hopkins University JoVE 57845 Biologia
In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge Oliver A. Kent1, Charles Steenbergen2, Samarjit Das2 1Princess Margaret Cancer Centre, University of Toronto, 2Department of Pathology, Department of Cardiology, Johns Hopkins University JoVE 57845 Biologia