Kerensa Broersen

Publications

• Alzheimer's Disease: Treatment Strategies and Their Limitations
  International Journal of Molecular Sciences. Nov, 2022  |   Pubmed ID: 36430432
• Use of Standard U-bottom and V-bottom Well Plates to Generate Neuroepithelial Embryoid Bodies
  PloS One. 2022  |   Pubmed ID: 35536781
• Engineering Organoids for Modeling of Phenylketonuria
  Frontiers in Molecular Neuroscience. 2021  |   Pubmed ID: 35082602
• A Review of Oxidative Stress Products and Related Genes in Early Alzheimer's Disease
  Journal of Alzheimer's Disease : JAD. 2021  |   Pubmed ID: 34420962
• Cross-seeding of Alpha-synuclein Aggregation by Amyloid Fibrils of Food Proteins
  The Journal of Biological Chemistry. 2021  |   Pubmed ID: 33539920
• Plant Isoquinoline Alkaloids As Potential Neurodrugs: A Comparative Study of the Effects of Benzo[c]phenanthridine and Berberine-based Compounds on β-amyloid Aggregation
  Chemico-biological Interactions. Jan, 2021  |   Pubmed ID: 33098838
• Milk Processing Affects Structure, Bioavailability and Immunogenicity of β-lactoglobulin
  Foods (Basel, Switzerland). Jul, 2020  |   Pubmed ID: 32635246
• Exposure of a Cryptic Hsp70 Binding Site Determines the Cytotoxicity of the ALS-associated SOD1-mutant A4V
  Protein Engineering, Design & Selection : PEDS. Dec, 2019  |   Pubmed ID: 32399571
• Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer's Disease
  Journal of Alzheimer's Disease : JAD. 2019  |   Pubmed ID: 31744008
• Apolipoprotein E Associated with Reconstituted High-density Lipoprotein-like Particles is Protected from Aggregation
  FEBS Letters. Jun, 2019  |   Pubmed ID: 31058310
• Benzodifurans for Biomedical Applications: BZ4, a Selective Anti-proliferative and Anti-amyloid Lead Compound
  Future Medicinal Chemistry. Feb, 2019  |   Pubmed ID: 30801198
• Searching for Improved Mimetic Peptides Inhibitors Preventing Conformational Transition of Amyloid-β Monomer
  Bioorganic Chemistry. Dec, 2018  |   Pubmed ID: 30144634
• Structural and Aggregation Properties of Alpha-Synuclein Linked to Phospholipase A2 Action
  Protein and Peptide Letters. 2018  |   Pubmed ID: 29577851
• Optimized Triton X-114 Assisted Lipopolysaccharide (LPS) Removal Method Reveals the Immunomodulatory Effect of Food Proteins
  PloS One. 2017  |   Pubmed ID: 28355240
• Characterization of Insulin-degrading Enzyme-mediated Cleavage of Aβ in Distinct Aggregation States
  Biochimica Et Biophysica Acta. Jun, 2016  |   Pubmed ID: 26968463
• Could Ecosystem Management Provide a New Framework for Alzheimer's Disease?
  Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Jan, 2016  |   Pubmed ID: 26341147
• Two Distinct β-sheet Structures in Italian-mutant Amyloid-beta Fibrils: a Potential Link to Different Clinical Phenotypes
  Cellular and Molecular Life Sciences : CMLS. Dec, 2015  |   Pubmed ID: 26190022
• New Mimetic Peptides Inhibitors of Αβ Aggregation. Molecular Guidance for Rational Drug Design
  European Journal of Medicinal Chemistry. May, 2015  |   Pubmed ID: 25805447
• A Comparative Analysis of the Aggregation Behavior of Amyloid-β Peptide Variants
  FEBS Letters. Nov, 2012  |   Pubmed ID: 23103738
• Molecular Plasticity Regulates Oligomerization and Cytotoxicity of the Multipeptide-length Amyloid-β Peptide Pool
  The Journal of Biological Chemistry. Oct, 2012  |   Pubmed ID: 22992745
• The Mechanism of γ-Secretase Dysfunction in Familial Alzheimer Disease
  The EMBO Journal. May, 2012  |   Pubmed ID: 22505025
• Structural Basis for Increased Toxicity of Pathological Aβ42:aβ40 Ratios in Alzheimer Disease
  The Journal of Biological Chemistry. Feb, 2012  |   Pubmed ID: 22157754
• Neurotoxicity of Alzheimer's Disease Aβ Peptides is Induced by Small Changes in the Aβ42 to Aβ40 Ratio
  The EMBO Journal. Oct, 2010  |   Pubmed ID: 20818335