Masamitsu Iino Department of Pharmacology, Graduate School of Medicine The University of Tokyo Biography Publications Institution JoVE Articles Masamitsu Iino has not added a biography. If you are Masamitsu Iino and would like to personalize this page please email our Author Liaison for assistance. Publications Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death EBioMedicine. Aug, 2016 | Pubmed ID: 27544065 Genetically Encoded Fluorescent Indicators for Organellar Calcium Imaging Biophysical Journal. Jul, 2016 | Pubmed ID: 27477268 Whisker Experience-dependent MGluR Signaling Maintains Synaptic Strength in the Mouse Adolescent Cortex The European Journal of Neuroscience. Aug, 2016 | Pubmed ID: 27225340 Visualization of Ca2+ Filling Mechanisms Upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2015 | Pubmed ID: 26631466 Neuronal Regulation of Schwann Cell Mitochondrial Ca(2+) Signaling During Myelination Cell Reports. Sep, 2015 | Pubmed ID: 26365190 Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region PloS One. 2015 | Pubmed ID: 26115329 In Vivo Visualization of Subtle, Transient, and Local Activity of Astrocytes Using an Ultrasensitive Ca(2+) Indicator Cell Reports. Jul, 2014 | Pubmed ID: 24981861 Imaging Intraorganellar Ca2+ at Subcellular Resolution Using CEPIA Nature Communications. 2014 | Pubmed ID: 24923787 Calcium-dependent N-cadherin Up-regulation Mediates Reactive Astrogliosis and Neuroprotection After Brain Injury Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23798419 Nitric Oxide-induced Calcium Release: Activation of Type 1 Ryanodine Receptor by Endogenous Nitric Oxide Channels (Austin, Tex.). Jan, 2013 | Pubmed ID: 23247505 β-catenin Regulates Parathyroid Hormone/parathyroid Hormone-related Protein Receptor Signals and Chondrocyte Hypertrophy Through Binding to the Intracellular C-terminal Region of the Receptor Arthritis and Rheumatism. Feb, 2013 | Pubmed ID: 23124878 Nitric Oxide-induced Calcium Release Via Ryanodine Receptors Regulates Neuronal Function The EMBO Journal. Jan, 2012 | Pubmed ID: 22036948 Visualization of Glutamate As a Volume Transmitter The Journal of Physiology. Feb, 2011 | Pubmed ID: 21115644 Imaging of Ca2+ and Related Signaling Molecules and Investigation of Their Functions in the Brain Antioxidants & Redox Signaling. Apr, 2011 | Pubmed ID: 20615120 Inositol 1,4,5-trisphosphate Signaling Maintains the Activity of Glutamate Uptake in Bergmann Glia The European Journal of Neuroscience. Nov, 2010 | Pubmed ID: 20958799 Imaging Extrasynaptic Glutamate Dynamics in the Brain Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20308566 Spatiotemporal Dynamics of Ca2+ Signaling and Its Physiological Roles Proceedings of the Japan Academy. Series B, Physical and Biological Sciences. 2010 | Pubmed ID: 20228624 Temporal Switching and Cell-to-cell Variability in Ca2+ Release Activity in Mammalian Cells Molecular Systems Biology. 2009 | Pubmed ID: 19293827 Functional Crosstalk Between Cell-surface and Intracellular Channels Mediated by Junctophilins Essential for Neuronal Functions Cerebellum (London, England). 2008 | Pubmed ID: 18607668 환경에 민감한 Photosensitizer 여 내의 산소 생성의 전환 통해 단백질 기능의 선택적 Photoinactivation Proceedings of the National Academy of Sciences of the United States of America. Jan, 2008 | Pubmed ID: 18172220 Identification of New Functions of Ca2+ Release from Intracellular Stores in Central Nervous System Biochemical and Biophysical Research Communications. Apr, 2008 | Pubmed ID: 18053793 Regulation of Long-term Depression and Climbing Fiber Territory by Glutamate Receptor Delta2 at Parallel Fiber Synapses Through Its C-terminal Domain in Cerebellar Purkinje Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2007 | Pubmed ID: 17978051 Involvement of Protein-tyrosine Phosphatase PTPMEG in Motor Learning and Cerebellar Long-term Depression The European Journal of Neuroscience. Oct, 2007 | Pubmed ID: 17953619 Postsynaptic GABAB Receptor Signalling Enhances LTD in Mouse Cerebellar Purkinje Cells The Journal of Physiology. Dec, 2007 | Pubmed ID: 17947316 Abnormal Features in Mutant Cerebellar Purkinje Cells Lacking Junctophilins Biochemical and Biophysical Research Communications. Nov, 2007 | Pubmed ID: 17904530 Regulation of Neurite Growth by Spontaneous Ca2+ Oscillations in Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2007 | Pubmed ID: 17699677 Induction of Cerebellar Long-term Depression Requires Activation of Calcineurin in Purkinje Cells Neuropharmacology. Jun, 2007 | Pubmed ID: 17485101 Optical Glutamate Sensor for Spatiotemporal Analysis of Synaptic Transmission The European Journal of Neuroscience. Apr, 2007 | Pubmed ID: 17445223 Junctophilin-mediated Channel Crosstalk Essential for Cerebellar Synaptic Plasticity The EMBO Journal. Apr, 2007 | Pubmed ID: 17347645 Regulation of Cell Functions by Ca2+ Oscillation Advances in Experimental Medicine and Biology. 2007 | Pubmed ID: 17278375 [Trends in Physiology] Nihon Seirigaku Zasshi. Journal of the Physiological Society of Japan. 2006 | Pubmed ID: 17175877 Coupling of STIM1 to Store-operated Ca2+ Entry Through Its Constitutive and Inducible Movement in the Endoplasmic Reticulum Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17075073 Ca2+ Lightning Conveys Cell-cell Contact Information Inside the Cells EMBO Reports. Nov, 2006 | Pubmed ID: 17039254 Postsynaptic Inositol 1,4,5-trisphosphate Signaling Maintains Presynaptic Function of Parallel Fiber-Purkinje Cell Synapses Via BDNF Proceedings of the National Academy of Sciences of the United States of America. May, 2006 | Pubmed ID: 16709674 Ca2+-dependent Inositol 1,4,5-trisphosphate and Nitric Oxide Signaling in Cerebellar Neurons Journal of Pharmacological Sciences. 2006 | Pubmed ID: 16682789 Ca2+ Shuttling Between Endoplasmic Reticulum and Mitochondria Underlying Ca2+ Oscillations EMBO Reports. Apr, 2006 | Pubmed ID: 16415789 Maintenance of Presynaptic Function by AMPA Receptor-mediated Excitatory Postsynaptic Activity in Adult Brain Proceedings of the National Academy of Sciences of the United States of America. Dec, 2005 | Pubmed ID: 16357208 [작은 분자 기반 발 도움 레이저 비활성화 하 여 세포내 막 단백질 기능 분석] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Aug, 2005 | Pubmed ID: 16104611 NO Signalling Decodes Frequency of Neuronal Activity and Generates Synapse-specific Plasticity in Mouse Cerebellum The Journal of Physiology. Aug, 2005 | Pubmed ID: 15919714 BAD Detects Coincidence of G2/M Phase and Growth Factor Deprivation to Regulate Apoptosis The Journal of Biological Chemistry. Jul, 2005 | Pubmed ID: 15901741 Rapid Ca2+-dependent Increase in Oxygen Consumption by Mitochondria in Single Mammalian Central Neurons Cell Calcium. Apr, 2005 | Pubmed ID: 15755497 System-level Identification of Transcriptional Circuits Underlying Mammalian Circadian Clocks Nature Genetics. Feb, 2005 | Pubmed ID: 15665827 Real-time Imaging of Myosin II Regulatory Light-chain Phosphorylation Using a New Protein Biosensor The Biochemical Journal. Jan, 2005 | Pubmed ID: 15362955 Cross Talk Between Metabotropic and Ionotropic Glutamate Receptor-mediated Signaling in Parallel Fiber-induced Inositol 1,4,5-trisphosphate Production in Cerebellar Purkinje Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2004 | Pubmed ID: 15509738 멤브레인 Permeant 프로브를 사용 하 여 Inositol 1,4,5 Trisphosphate 수용 체의 레이저 비활성화 하 여 세포내 Ca2 + 역학의 수정 Chemistry & Biology. Aug, 2004 | Pubmed ID: 15324806 Molecular-timetable Methods for Detection of Body Time and Rhythm Disorders from Single-time-point Genome-wide Expression Profiles Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004 | Pubmed ID: 15273285 Universality and Flexibility in Gene Expression from Bacteria to Human Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14999098 [Ca2+ Imaging in Interstitial Cells of Cajal During Rhythmic Activity] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Mar, 2004 | Pubmed ID: 14993727 Enzymatic Production of RNAi Libraries from CDNAs Nature Genetics. Feb, 2004 | Pubmed ID: 14704669 Isoform-specific Phosphorylation of Metabotropic Glutamate Receptor 5 by Protein Kinase C (PKC) Blocks Ca2+ Oscillation and Oscillatory Translocation of Ca2+-dependent PKC The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14561742 [Not Available] Clinical Calcium. Apr, 2003 | Pubmed ID: 15775120 NFAT Functions As a Working Memory of Ca2+ Signals in Decoding Ca2+ Oscillation The EMBO Journal. Aug, 2003 | Pubmed ID: 12881417 Inositol 1,4,5 Trisphosphate 수용 체 합성 작은 분자 프로브를 사용 하 여의 Spatiotemporal 레이저 비활성화 Chemistry & Biology. Jun, 2003 | Pubmed ID: 12837383 Functional and Biochemical Analysis of the Type 1 Inositol (1,4,5)-trisphosphate Receptor Calcium Sensor Biophysical Journal. Jul, 2003 | Pubmed ID: 12829484 Intracellular Delivery of Glutathione S-transferase into Mammalian Cells Biochemical and Biophysical Research Communications. Jun, 2003 | Pubmed ID: 12763035 Glucose Metabolism and Glutamate Analog Acutely Alkalinize PH of Insulin Secretory Vesicles of Pancreatic Beta-cells American Journal of Physiology. Endocrinology and Metabolism. Aug, 2003 | Pubmed ID: 12644449 Effects of Insulin-like Growth Factor I on Climbing Fibre Synapse Elimination During Cerebellar Development The European Journal of Neuroscience. Feb, 2003 | Pubmed ID: 12581172 Switch to Anaerobic Glucose Metabolism with NADH Accumulation in the Beta-cell Model of Mitochondrial Diabetes. Characteristics of BetaHC9 Cells Deficient in Mitochondrial DNA Transcription The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12169697 Molecular Basis and Physiological Functions of Dynamic Ca2+ Signalling in Smooth Muscle Cells Novartis Foundation Symposium. 2002 | Pubmed ID: 12164306 Family Affairs of Intracellular Ca(2+)-release Channels The Journal of Physiology. Aug, 2002 | Pubmed ID: 12154169 A Transcription Factor Response Element for Gene Expression During Circadian Night Nature. Aug, 2002 | Pubmed ID: 12152080 Intercellular Coupling Mechanism for Synchronized and Noise-resistant Circadian Oscillators Journal of Theoretical Biology. Jun, 2002 | Pubmed ID: 12151263 The High-affinity Calcium[bond]calmodulin-binding Site Does Not Play a Role in the Modulation of Type 1 Inositol 1,4,5-trisphosphate Receptor Function by Calcium and Calmodulin The Biochemical Journal. Aug, 2002 | Pubmed ID: 11972451 Inositol 1,4,5 Trisphosphate Analogues의 1 인산에서 소수 수정 수용 체 바인딩을 강화 Bioorganic & Medicinal Chemistry Letters. Mar, 2002 | Pubmed ID: 11958992 Novel Mutations in C-terminal Channel Region of the Ryanodine Receptor in Malignant Hyperthermia Patients Japanese Journal of Pharmacology. Feb, 2002 | Pubmed ID: 11928716 Functional Characterization of the Type 1 Inositol 1,4,5-trisphosphate Receptor Coupling Domain SII(+/-) Splice Variants and the Opisthotonos Mutant Form Biophysical Journal. Apr, 2002 | Pubmed ID: 11916857 Transient Receptor Potential 1 Regulates Capacitative Ca(2+) Entry and Ca(2+) Release from Endoplasmic Reticulum in B Lymphocytes The Journal of Experimental Medicine. Mar, 2002 | Pubmed ID: 11901194 Genome-wide Transcriptional Orchestration of Circadian Rhythms in Drosophila The Journal of Biological Chemistry. Apr, 2002 | Pubmed ID: 11854264 Simultaneous Imaging of Ca2+ Signals in Interstitial Cells of Cajal and Longitudinal Smooth Muscle Cells During Rhythmic Activity in Mouse Ileum The Journal of Physiology. Feb, 2002 | Pubmed ID: 11826167 Two-photon Excitation Imaging of Pancreatic Islets with Various Fluorescent Probes Diabetes. Feb, 2002 | Pubmed ID: 11815453 Phosphatidylinositol 3-kinase Suppresses Glucose-stimulated Insulin Secretion by Affecting Post-cytosolic [Ca(2+)] Elevation Signals Diabetes. Jan, 2002 | Pubmed ID: 11756327 Electroporation에 의해 쥐 좌골 신경의 슈반 세포로 생체 내 유전자 전달에 Daisuke Ino1,2, Masamitsu Iino1 1Department of Pharmacology, Graduate School of Medicine, The University of Tokyo, 2Laboratory for Cell Polarity Regulation, Quantitative Biology Center, RIKEN Neuroscienze
Electroporation에 의해 쥐 좌골 신경의 슈반 세포로 생체 내 유전자 전달에 Daisuke Ino1,2, Masamitsu Iino1 1Department of Pharmacology, Graduate School of Medicine, The University of Tokyo, 2Laboratory for Cell Polarity Regulation, Quantitative Biology Center, RIKEN Neuroscienze