Ronald T. Hay

Publications

• Tetramerization-defects of P53 Result in Aberrant Ubiquitylation and Transcriptional Activity
  Molecular Oncology. Apr, 2014  |   Pubmed ID: 24816189
• Proteome-Wide Identification of SUMO2 Modification Sites
  Science Signaling. 2014  |   Pubmed ID: 24782567
• E3 Ubiquitin Ligase HOIP Attenuates Apoptotic Cell Death Induced by Cisplatin
  Cancer Research. Apr, 2014  |   Pubmed ID: 24686174
• SUMO Chain-induced Dimerization Activates RNF4
  Molecular Cell. Mar, 2014  |   Pubmed ID: 24656128
• PML Isoforms in Response to Arsenic: High Resolution Analysis of PML Body Structure and Degradation Characteristics
  Journal of Cell Science. Nov, 2013  |   Pubmed ID: 24190887
• BC-box Protein Domain-related Mechanism for VHL Protein Degradation
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2013  |   Pubmed ID: 24145437
• A Role for Paralog-specific Sumoylation in Histone Deacetylase 1 Stability
  Journal of Molecular Cell Biology. Dec, 2013  |   Pubmed ID: 24068740
• Ube2W Conjugates Ubiquitin to α-amino Groups of Protein N-termini
  The Biochemical Journal. Jul, 2013  |   Pubmed ID: 23560854
• Decoding the SUMO Signal
  Biochemical Society Transactions. Apr, 2013  |   Pubmed ID: 23514139
• The P-body Component USP52/PAN2 is a Novel Regulator of HIF1A MRNA Stability
  The Biochemical Journal. Apr, 2013  |   Pubmed ID: 23398456
• Reanalysis of Phosphoproteomics Data Uncovers ADP-ribosylation Sites
  Nature Methods. Aug, 2012  |   Pubmed ID: 22847107
• Structure of a RING E3 Ligase and Ubiquitin-loaded E2 Primed for Catalysis
  Nature. Sep, 2012  |   Pubmed ID: 22842904
• SUMO-targeted Ubiquitin E3 Ligase RNF4 is Required for the Response of Human Cells to DNA Damage
  Genes & Development. Jun, 2012  |   Pubmed ID: 22661230
• SUMOylation of HNF4α Regulates Protein Stability and Hepatocyte Function
  Journal of Cell Science. Aug, 2012  |   Pubmed ID: 22505616
• Detection and Quantitation of SUMO Chains by Mass Spectrometry
  Methods in Molecular Biology (Clifton, N.J.). 2012  |   Pubmed ID: 22350890
• Stable-isotope Labeling with Amino Acids in Nematodes
  Nature Methods. 2011  |   Pubmed ID: 21874007
• Mechanism of Ubiquitylation by Dimeric RING Ligase RNF4
  Nature Structural & Molecular Biology. Sep, 2011  |   Pubmed ID: 21857666
• Absolute SILAC-compatible Expression Strain Allows Sumo-2 Copy Number Determination in Clinical Samples
  Journal of Proteome Research. Oct, 2011  |   Pubmed ID: 21830832
• Comparative Proteomic Analysis Identifies a Role for SUMO in Protein Quality Control
  Science Signaling. 2011  |   Pubmed ID: 21693764
• Purification and Identification of Endogenous PolySUMO Conjugates
  EMBO Reports. Feb, 2011  |   Pubmed ID: 21252943
• The SUMO Protease SENP6 is a Direct Regulator of PML Nuclear Bodies
  Molecular Biology of the Cell. Jan, 2011  |   Pubmed ID: 21148299
• Functional Interactions Between Ubiquitin E2 Enzymes and TRIM Proteins
  The Biochemical Journal. Mar, 2011  |   Pubmed ID: 21143188
• Arsenic-induced SUMO-dependent Recruitment of RNF4 into PML Nuclear Bodies
  Molecular Biology of the Cell. Dec, 2010  |   Pubmed ID: 20943951
• SUMOylation of the GTPase Rac1 is Required for Optimal Cell Migration
  Nature Cell Biology. Nov, 2010  |   Pubmed ID: 20935639
• Post-translational Modification by SUMO
  Toxicology. Dec, 2010  |   Pubmed ID: 20674646
• High-stringency Tandem Affinity Purification of Proteins Conjugated to Ubiquitin-like Moieties
  Nature Protocols. May, 2010  |   Pubmed ID: 20431533
• Oligomerization Conditions Mdm2-mediated Efficient P53 Polyubiquitylation but Not Its Proteasomal Degradation
  The International Journal of Biochemistry & Cell Biology. May, 2010  |   Pubmed ID: 20080206
• Iso-seco-tanapartholides: Isolation, Synthesis and Biological Evaluation
  European Journal of Organic Chemistry. Nov, 2009  |   Pubmed ID: 23606807
• Detection of Protein SUMOylation in Vivo
  Nature Protocols. 2009  |   Pubmed ID: 19730420
• An Additional Role for SUMO in Ubiquitin-mediated Proteolysis
  Nature Reviews. Molecular Cell Biology. Aug, 2009  |   Pubmed ID: 19474794
• System-wide Changes to SUMO Modifications in Response to Heat Shock
  Science Signaling. 2009  |   Pubmed ID: 19471022
• Characterization of SENP7, a SUMO-2/3-specific Isopeptidase
  The Biochemical Journal. Jul, 2009  |   Pubmed ID: 19392659
• FRET-based in Vitro Assays for the Analysis of SUMO Protease Activities
  Methods in Molecular Biology (Clifton, N.J.). 2009  |   Pubmed ID: 19107423
• Medea SUMOylation Restricts the Signaling Range of the Dpp Morphogen in the Drosophila Embryo
  Genes & Development. Sep, 2008  |   Pubmed ID: 18794353
• Single-stranded DNA-binding Protein HSSB1 is Critical for Genomic Stability
  Nature. May, 2008  |   Pubmed ID: 18449195
• RNF4 is a Poly-SUMO-specific E3 Ubiquitin Ligase Required for Arsenic-induced PML Degradation
  Nature Cell Biology. May, 2008  |   Pubmed ID: 18408734
• Conjugation of Human Topoisomerase 2 Alpha with Small Ubiquitin-like Modifiers 2/3 in Response to Topoisomerase Inhibitors: Cell Cycle Stage and Chromosome Domain Specificity
  Cancer Research. Apr, 2008  |   Pubmed ID: 18381449
• Quantitative Analysis of Multi-protein Interactions Using FRET: Application to the SUMO Pathway
  Protein Science : a Publication of the Protein Society. Apr, 2008  |   Pubmed ID: 18359863
• NF-kappaB is a Critical Regulator of the Survival of Rodent and Human Hepatic Myofibroblasts
  Journal of Hepatology. Apr, 2008  |   Pubmed ID: 18279996
• Ribosomal Proteins Are Targets for the NEDD8 Pathway
  EMBO Reports. Mar, 2008  |   Pubmed ID: 18274552
• In Vivo Identification of Human Small Ubiquitin-like Modifier Polymerization Sites by High Accuracy Mass Spectrometry and an in Vitro to in Vivo Strategy
  Molecular & Cellular Proteomics : MCP. Jan, 2008  |   Pubmed ID: 17938407
• SUMO Modification Regulates MafB-driven Macrophage Differentiation by Enabling Myb-dependent Transcriptional Repression
  Molecular and Cellular Biology. Aug, 2007  |   Pubmed ID: 17548468
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  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007  |   Pubmed ID: 17360386