Steven L. Carroll Department of Pathology and Laboratory Medicine Medical University of South Carolina Biography Publications Institution JoVE Articles Steven L. Carroll has not added a biography. If you are Steven L. Carroll and would like to personalize this page please email our Author Liaison for assistance. Publications Down Syndrome Biobank Consortium: A Perspective Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Mar, 2024 | Pubmed ID: 38270275 Inhibition of Erb-B2 Receptor Tyrosine Kinase 3 and Associated Regulatory Pathways Potently Impairs Malignant Peripheral Nerve Sheath Tumor Proliferation and Survival The American Journal of Pathology. Sep, 2023 | Pubmed ID: 37328102 LPAR1 and Aberrantly Expressed LPAR3 Differentially Promote the Migration and Proliferation of Malignant Peripheral Nerve Sheath Tumor Cells Glia. Mar, 2023 | Pubmed ID: 36416236 Priorities in Biobanking Research: A Report on the 2021 ISBER Round Table Biopreservation and Biobanking. Feb, 2023 | Pubmed ID: 35507966 Developmental, Neurochemical, and Behavioral Analyses of ErbB4 Cyt-1 Knockout Mice Journal of Neurochemistry. Jun, 2022 | Pubmed ID: 35523590 The RASopathies: Biology, Genetics and Therapeutic Options Advances in Cancer Research. 2022 | Pubmed ID: 35101235 Suppression of Fli-1 Protects Against Pericyte Loss and Cognitive Deficits in Alzheimer's Disease Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2022 | Pubmed ID: 35038582 R-Ras Subfamily Proteins Elicit Distinct Physiologic Effects and Phosphoproteome Alterations in Neurofibromin-null MPNST Cells Cell Communication and Signaling : CCS. Sep, 2021 | Pubmed ID: 34530870 The Role of R-Ras Proteins in Normal and Pathologic Migration and Morphologic Change The American Journal of Pathology. Sep, 2021 | Pubmed ID: 34111428 The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment International Journal of Molecular Sciences. Apr, 2021 | Pubmed ID: 33925820 Establishment and Genomic Characterization of a Sporadic Malignant Peripheral Nerve Sheath Tumor Cell Line Scientific Reports. Mar, 2021 | Pubmed ID: 33707600 Each Patient is a Research Biorepository: Informatics-enabled Research on Surplus Clinical Specimens Via the Living BioBank Journal of the American Medical Informatics Association : JAMIA. 01, 2021 | Pubmed ID: 33166379 Chemoembolizing Hepatocellular Carcinoma with Microsphere Cored with Arsenic Trioxide Microcrystal Drug Delivery. Nov, 2020 | Pubmed ID: 33307843 Assessing Interobserver Variability and Accuracy in the Histological Diagnosis and Classification of Cutaneous Neurofibromass Neuro-oncology Advances. Jul, 2020 | Pubmed ID: 32642737 Serum Pro-BDNF Levels Correlate with Phospho-tau Staining in Alzheimer's Disease Neurobiology of Aging. 03, 2020 | Pubmed ID: 31882186 Salinomycin Targets the Genome of Radioresistant Cells in Glioblastomas Neuro-oncology. 02, 2020 | Pubmed ID: 31784742 The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease Molecular & Cellular Proteomics : MCP. 01, 2020 | Pubmed ID: 31699905 Mechanisms of Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Action in Human Neoplasia The American Journal of Pathology. 10, 2019 | Pubmed ID: 31351986 ErbB4 Promotes Malignant Peripheral Nerve Sheath Tumor Pathogenesis Via Ras-independent Mechanisms Cell Communication and Signaling : CCS. 07, 2019 | Pubmed ID: 31291965 The Evolution and Multi-molecular Properties of NF1 Cutaneous Neurofibromas Originating from C-fiber Sensory Endings and Terminal Schwann Cells at Normal Sites of Sensory Terminations in the Skin PloS One. 2019 | Pubmed ID: 31107888 Complex Patterns of GABAergic Neuronal Deficiency and Type 2 Potassium-Chloride Cotransporter Immaturity in Human Focal Cortical Dysplasia Journal of Neuropathology and Experimental Neurology. 04, 2019 | Pubmed ID: 30856249 Cutaneous Neurofibromas: Current Clinical and Pathologic Issues Neurology. 07, 2018 | Pubmed ID: 29987130 Oridonin Inhibits Aberrant AKT Activation in Breast Cancer Oncotarget. May, 2018 | Pubmed ID: 29844859 Pathology of NNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease Neuroscience. 08, 2018 | Pubmed ID: 29782905 Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms Advances in Anatomic Pathology. Sep, 2018 | Pubmed ID: 29762158 Rare Coding Variants in PLCG2, ABI3, and TREM2 Implicate Microglial-mediated Innate Immunity in Alzheimer's Disease Nature Genetics. 09, 2017 | Pubmed ID: 28714976 The Molecular and Morphologic Structures That Make Saltatory Conduction Possible in Peripheral Nerve Journal of Neuropathology and Experimental Neurology. 04, 2017 | Pubmed ID: 28340093 BH3 Mimetics Suppress CXCL12 Expression in Human Malignant Peripheral Nerve Sheath Tumor Cells Oncotarget. Jan, 2017 | Pubmed ID: 28055968 Neuronal Exosomes Reveal Alzheimer's Disease Biomarkers in Down Syndrome Alzheimer's & Dementia : the Journal of the Alzheimer's Association. May, 2017 | Pubmed ID: 27755974 Current Status and Recommendations for Biomarkers and Biobanking in Neurofibromatosis Neurology. Aug, 2016 | Pubmed ID: 27527649 STAT1 and NF-κB Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells Molecular Cancer Research : MCR. 05, 2016 | Pubmed ID: 26883073 The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors As a Paradigm for Cross-Species Comparative Oncogenomics The American Journal of Pathology. Mar, 2016 | Pubmed ID: 26740486 Classic Ras Proteins Promote Proliferation and Survival Via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells Journal of Neuropathology and Experimental Neurology. Jun, 2015 | Pubmed ID: 25946318 Combinatorial Therapy with Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades Journal of Neuropathology and Experimental Neurology. Nov, 2014 | Pubmed ID: 25289889 CLDN2 と PRSS1 PRSS2 の座における遺伝子変異と散発的なアルコール関連の膵炎のリスクを変更します。 Nature Genetics. Nov, 2012 | Pubmed ID: 23143602 パンのErbB阻害剤PD168393は、悪性末梢神経鞘腫瘍細胞のライソゾーム機能障害誘発性アポトーシスを増強する Neuro-oncology. Jan, 2012 | Pubmed ID: 22259051 シュワン細胞腫瘍の発症を促進する分子機構 Acta Neuropathologica. Dec, 2011 | Pubmed ID: 22160322 遺伝子改変マウスモデルでは、末梢神経系の神経線維腫症タイプIに関連した腫瘍の発症機序に新たな光を当てる Brain Research Bulletin. Aug, 2011 | Pubmed ID: 21855613 MS4A4/MS4A6E、CD2AP、CD33とEPHA1で共通のバリアントは、遅発性アルツハイマー病と関連している Nature Genetics. May, 2011 | Pubmed ID: 21460841 タモキシフェンは、エストロゲン受容体に依存しない方法で悪性末梢神経鞘腫瘍の増殖を抑制する Neuro-oncology. Jan, 2011 | Pubmed ID: 21075781 7p21におけるコモンバリアントは、TDP-43封入体を有する前頭側頭葉変性症と関連付けられている Nature Genetics. Mar, 2010 | Pubmed ID: 20154673 Neuregulin-1 Beta and Neuregulin-1 Alpha Differentially Affect the Migration and Invasion of Malignant Peripheral Nerve Sheath Tumor Cells Glia. Nov, 2009 | Pubmed ID: 19306381 NF1におけるシュワン細胞リネージュフォーム腫瘍はどのようにしていますか？ Glia. Nov, 2008 | Pubmed ID: 18803326 低酸素虚血後海馬ニューロン新生亜におけるc-Fosとカスパーゼ3の差動の活性化 Journal of Neuroscience Research. Apr, 2008 | Pubmed ID: 18030677 BH3のみのアポトーシスのBcl-2ファミリーメンバーの病毒とプーマメディ神経前駆細胞死 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2006 | Pubmed ID: 16822983 運動ニューロンアポトーシスにおけるβ-ニューレグリンと神経栄養因子との相互作用 Journal of Neurochemistry. Apr, 2006 | Pubmed ID: 16524373 ニューレグリンの成長因子とそののErbB受容体は神経鞘腫の腫瘍形成の潜在的なシグナリングネットワークを形成 Journal of Neuropathology and Experimental Neurology. Feb, 2006 | Pubmed ID: 16462207 Neuregulin-1/ErbBシグナル伝達経路の活性化はヒト悪性末梢神経鞘腫瘍では腫瘍、シュワン細胞の増殖を促進 Oncogene. Aug, 2005 | Pubmed ID: 15897877 ニューレグリン-1はヒトアストロサイト、神経膠腫細胞の生存率を高める Glia. Aug, 2005 | Pubmed ID: 15812817 腫瘍抑制遺伝子変異とNF1関連末梢神経鞘腫瘍の病因における増殖因子シグナル：II。シグナリング調節不全の成長因子の役割 Journal of Neuropathology and Experimental Neurology. Jan, 2005 | Pubmed ID: 15715079 ファイバー修飾アデノウイルスベクターを用いた神経膠細胞への改良された遺伝子デリバリー Biochemical and Biophysical Research Communications. Mar, 2005 | Pubmed ID: 15708001 糖尿病変調された遺伝子発現の神経節に固有のパターンは、神経軸索ジストロフィーの開発する前に椎と傍脊柱交感神経節で確立されている Journal of Neuropathology and Experimental Neurology. Nov, 2004 | Pubmed ID: 15581182 腫瘍抑制遺伝子変異とNF1関連末梢神経鞘腫瘍の病因における増殖因子シグナル。 I.癌抑制遺伝子変異の役割 Journal of Neuropathology and Experimental Neurology. Nov, 2004 | Pubmed ID: 15581179 ニューレグリン-1βは培養海馬神経細胞における神経突起の伸長と分枝を誘導する Molecular and Cellular Neurosciences. Dec, 2004 | Pubmed ID: 15555917 のErbB膜貫通型チロシンキナーゼ受容体は、坐骨神経に突出感覚と運動ニューロンで表される The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Oct, 2004 | Pubmed ID: 15385576 Neuregulin-1/erbBシグナル伝達経路の恒常的活性化はヒト末梢神経上皮腫細胞株の増殖を促進する Journal of Neuro-oncology. Feb, 2004 | Pubmed ID: 15015657 トランスジェニックマウスの肥厚性ニューロパシーおよび悪性末梢神経鞘腫瘍シュワン細胞を鞘に過剰発現するグリア成長因子Beta3の The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2003 | Pubmed ID: 12917360 Neuregulin-1/ErbB受容体シグナル伝達経路の恒常的活性化は腫瘍シュワン細胞株の増殖に必須である Glia. Aug, 2003 | Pubmed ID: 12838503 リゾホスファチジン酸はAxotomized坐骨神経から分離された大人のシュワン細胞の増殖を促進する Journal of Neuropathology and Experimental Neurology. May, 2003 | Pubmed ID: 12769191 ニューレグリン-1はヒトアストロサイト神経膠腫細胞の運動性と移行を強化 The Journal of Biological Chemistry. Jun, 2003 | Pubmed ID: 12600989 ニューレグリン1とErbB4の免疫反応性はアルツハイマー病の脳とアルツハイマー病のトランスジェニックモデルにおける老人斑に関連付けられている Journal of Neuropathology and Experimental Neurology. Jan, 2003 | Pubmed ID: 12528817 Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors Dorea P. Jenkins1, Brittany Turner-Ivey1,2, Jody Fromm Longo1, Steven L. Carroll1,2 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Hollings Cancer Center, Medical University of South Carolina JoVE 65740 Ricerca sul cancro Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE Brittany Turner-Ivey1, Jody Fromm Longo2, Dorea P. Jenkins2, Stephen T. Guest3, Steven L. Carroll1,2 1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor JoVE 65430 Ricerca sul cancro 悪性末梢神経鞘腫瘍細胞におけるフロックス対立遺伝子の Ex vivo アブレーションによる腫瘍形成における遺伝子機能の定義 Jody Fromm Longo1, Stephanie N. Brosius2,3, Steven L. Carroll1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Department of Pediatrics and Neurology, Perelman School of Medicine of the University of Pennsylvania, 3Division of Child Neurology, Children's Hospital of Philadelphia JoVE 62740 Ricerca sul cancro のために人間のルシフェラーゼ-タグ付き悪性末梢神経鞘腫瘍細胞の同所Xenografting in vivoでテスト Amy N. Turk1, Stephanie J. Byer1, Kurt R. Zinn2, Steven L. Carroll1,3 1Department of Pathology, University of Alabama at Birmingham - UAB, 2Department of Radiology, University of Alabama at Birmingham - UAB, 3Department of Cell Biology and Neurobiology, University of Alabama at Birmingham - UAB JoVE 2558 Medicina
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors Dorea P. Jenkins1, Brittany Turner-Ivey1,2, Jody Fromm Longo1, Steven L. Carroll1,2 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Hollings Cancer Center, Medical University of South Carolina JoVE 65740 Ricerca sul cancro
Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE Brittany Turner-Ivey1, Jody Fromm Longo2, Dorea P. Jenkins2, Stephen T. Guest3, Steven L. Carroll1,2 1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor JoVE 65430 Ricerca sul cancro
悪性末梢神経鞘腫瘍細胞におけるフロックス対立遺伝子の Ex vivo アブレーションによる腫瘍形成における遺伝子機能の定義 Jody Fromm Longo1, Stephanie N. Brosius2,3, Steven L. Carroll1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Department of Pediatrics and Neurology, Perelman School of Medicine of the University of Pennsylvania, 3Division of Child Neurology, Children's Hospital of Philadelphia JoVE 62740 Ricerca sul cancro
のために人間のルシフェラーゼ-タグ付き悪性末梢神経鞘腫瘍細胞の同所Xenografting in vivoでテスト Amy N. Turk1, Stephanie J. Byer1, Kurt R. Zinn2, Steven L. Carroll1,3 1Department of Pathology, University of Alabama at Birmingham - UAB, 2Department of Radiology, University of Alabama at Birmingham - UAB, 3Department of Cell Biology and Neurobiology, University of Alabama at Birmingham - UAB JoVE 2558 Medicina
