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Biology

Concept Videos

Molecular Biology

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Studying DNA and RNA

Finding cDNA Ends with RACE PCR

Description

Rapid Amplification of cDNA Ends, or RACE, helps scientists capture the full-length cDNA from an mRNA sequence. It works by linking a known internal region to the unknown sequence at either the 5' end or the 3' end. The method is widely used when the missing end of a gene needs to be identified.

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Transcript

Il cDNA completo non viene sempre ottenuto quando vengono scoperti per la prima volta nuovi trascritti genici di mRNA. Sequenze sconosciute alle estremità del modello di mRNA possono portare a cDNA parzialmente clonati.

La sequenza di questi cDNA parziali può essere estesa con una tecnica chiamata Rapid Amplification of cDNA Ends o RACE p...

Tags

Rapid Amplification cDNA EndsRACE TechniqueGene Specific PrimerHybrid PrimerPolymerase Chain ReactionDegenerate PrimerPoly C TailPoly G TailGI TailPrimer Optimization

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