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HIGH SCHOOL

Biology

Concept Videos

Molecular Biology

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Studying DNA and RNA

FISH for Chromosome and Pathogen Detection

Description

FISH is a DNA and RNA detection method used in cytogenetics and medical testing. FISH stands for fluorescence in situ hybridization. It uses labeled probes that bind to complementary DNA or RNA sequences on a chromosome or inside a cell.

The method was developed in the early 1980s and became wide...

Transcript

Fluorescence In situ Hybridization or FISH is a technique used to detect the location of specific genes or parts of genes on chromosomes within fixed cells.

In this technique, a fluorescently labeled single-stranded DNA is used as a probe to bind parts of chromosomes that contain a complementary DNA sequence, referred to as the t...

Tags

FISH TechniqueChromosome AnalysisDNA Probe BindingGenetic Disease DiagnosisMicrobial Pathogen DetectionFluorescence MicroscopyCCD Camera ImagingImage Processing SoftwareNucleic Acid Hybridization

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