How Genome Assemblies Are Updated

Genome assembly and genome annotation are key steps in genome analysis. Genome assembly puts DNA sequencing data back in the correct order to make a close copy of the original genome. Genome annotation then identifies functional parts on that assembled genome.

Assembling a genome is not simple. I...

The entire genome of an organism cannot be sequenced in continuous sequences - even the newest generation of sequencing technologies produce fragmented data from thousands of short DNA fragments ranging from 50-1000bp in length.

These short DNA sequences - called reads - need to be assembled to reconstruct the complete sequence of a genom...