Polystyrene Surface

Polystyrene surfaces are polymer interfaces widely used to support biological samples, cells, and biomolecules in laboratory devices. Their behavior depends on surface chemistry and wettability: untreated polystyrene is relatively hydrophobic, while plasma treatment, oxidation, or coating can introduce polar groups that improve protein adsorption and cell attachment. In bioengineering, these engineered surfaces enable cell culture, tissue models, microfluidic systems, and assay platforms, while differences in treatment and coating influence cell spreading, viability, differentiation, and measurement consistency. Understanding and controlling the polystyrene surface helps researchers reproduce experiments and tailor materials for biological applications.

Polystyrene Surface - Related Videos

Research

JoVE Journal - Chemistry

Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness

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Cited by 5 •

2018

A procedure for the synthesis of polystyrene-grafted multiwalled carbon nanotubes using successive chemical modification steps to selectively introduce the polymer chains to the sidewalls and their self-assembly via anisotropic patchiness is presented.

Using Polystyrene-block-poly(acrylic acid)-coated Metal Nanoparticles as Monomers for Their Homo- and Co-polymerization

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Cited by 1 •

2015

We report protocols for “polymerizing” various types of polymer-encapsulated metal nanoparticles into long chains of “homo-“ and “co-polymers”.

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

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Cited by 5 •

2016

Nanoscaled sea-island surfaces composed of thermoresponsive block copolymers were fabricated by the Langmuir-Schaefer method for controlling spontaneous cell adhesion and detachment. Both the preparation of the surface and the adhesion and detachment of cells on the surface were visualized.

Research

JoVE Journal - Neuroscience
Free Sample

Microvascular Embolism Mouse Model for In Vivo Two-photon Microscopy Using Fluorescent Polystyrene Microspheres

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2025

This protocol contains a thorough description of a step-by-step approach for a chronic cranial window and microvascular embolism mouse model optimized for in vivo two-photon microscopy imaging using fluorescent polystyrene microspheres.

Education

JoVE Core - Physics

Surface Tension and Surface Energy

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2023

When a paint brush is immersed in water, the bristles wave freely inside the water. When it is taken out, the bristles stick together. The reason behind this effect is surface tension. Consider a beaker filled with liquid. The bulk molecules in the liquid experience equal attractive forces on all sides with the surrounding molecules. However, the surface molecules experience a net attractive force downward due to the bulk molecules. The surface of the liquid behaves like a stretched membrane,...

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