Mesentery Removal
Mesentery Removal - Related Videos
18:30
Rat Mesentery Angiogenesis Assay
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Cited by 9 •
2011
Normal adult vascularized mammalian tissue that lacks physiologic angiogenesis and that has not been exposed to surgical intervention is used to study: (i) the initiation and development of angiogenesis following intraperitoneal administration of test agents; and (ii) modification of angiogenesis following systemic administration of selected test agents.
12:48
Microperfusion Technique to Investigate Regulation of Microvessel Permeability in Rat Mesentery
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Cited by 3 •
2015
The modified Landis technique enables paired measurement of the hydraulic conductivity of individual microvessels in the mesentery of normal and genetically modified rats under control and test conditions using microperfusion techniques. It provides a convenient method to evaluate mechanisms that regulate microvessel permeability and transvascular exchange under physiological conditions.
12:29
Rat Mesentery Exteriorization: A Model for Investigating the Cellular Dynamics Involved in Angiogenesis
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Cited by 19 •
2012
This article describes a simple model for stimulating angiogenesis in the rat mesentery. The model produces dramatic increases in capillary sprouting, vascular area and vascular density over a relatively short time course in a tissue that allows en face visualization of entire microvascular networks down to the single cell level.
07:26
Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel
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Cited by 49 •
2015
The FeCl3 induced thrombosis model in mice is described herein. A method to monitor thrombus growth by intravital microscopy observation on a mesenteric vessel and by blood flow measurement in the carotid artery is presented.
06:43
Rotary Evaporation to Remove Solvent
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2023
Source: Dr. Melanie Pribisko Yen and Grace Tang — California Institute of Technology Rotary evaporation is a technique most commonly used in organic chemistry to remove a solvent from a higher-boiling point compound of interest. The rotary evaporator, or "rotovap", was invented in 1950 by the chemist Lyman C. Craig. The primary use of a rotovap is to dry and purify samples for downstream applications. Its speed and ability to handle large volumes of solvent make rotary evaporation a preferred...
FAQs
The extent of excision is determined by which mesenteric tissues are associated with the tumor or considered at risk for disease spread. Removing involved lymph nodes or additional tissue can support more complete disease assessment, while preserving suitable structures may help retain important vascular and tissue relationships. This balance makes the surgical strategy relevant to both tumor control and postoperative evaluation.
Mesenteric lymphatics and lymph nodes provide information about possible pathways and sites of tumor dissemination. Examining involved nodes in the excised tissue can show whether disease has extended beyond the primary tumor region. These findings contribute to diagnosis, treatment planning, and research into how cancers spread through tissues associated with the intestines.
Surgeons ligate vessels that must be divided to remove the tumor or involved mesenteric tissue, while preserving vessels when they are not part of the tissue targeted for excision. This decision reflects the tumor’s relationship to surrounding structures and the intended surgical strategy. The resulting specimen can then support assessment of disease involvement and tissue margins.
Histopathology examines the excised specimen at the tissue level to assess tumor type, surgical margins, and lymph-node involvement. Tumor type helps characterize the disease, margins indicate whether tumor remains at the edges of the removed tissue, and node findings provide evidence about regional spread. Together, these results inform diagnosis, treatment planning, and outcome assessment.
The procedure includes dissecting the mesentery from surrounding tissues, managing vessels by ligating or preserving them as appropriate, and removing the tumor, involved lymph nodes, or tissue considered at risk for disease spread. The excised specimen is subsequently submitted for histopathologic examination. These steps connect the physical operation with postoperative disease characterization.
Cancer researchers use mesentery removal to evaluate surgical strategies, investigate patterns of tumor dissemination, and study tissue responses associated with disease and treatment. The procedure also produces specimens that can be examined for tumor characteristics, margins, and lymph-node involvement. Consequently, it links operative decisions with diagnostic findings and research on treatment planning and outcomes.