Patient Involvement
Patient Involvement - Related Videos
01:26
Antigens Involved in Adaptive Immunity
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2024
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it. Complete Antigens Complete antigens possess both immunogenicity and reactivity.
14:43
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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Cited by 40 •
2018
This manuscript describes the Research Prioritization by Affected Communities (RPAC) protocol and findings from its use with women at risk for preterm birth. Using the protocol, women identified and prioritized their unanswered questions about pregnancy, birth and neonatal care aimed at influencing research priority setting by funders and researchers.
12:50
Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
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Cited by 1 •
2017
Vascular endothelium tightly controls leukocyte recruitment. Inadequate leukocyte extravasation contributes to human inflammatory diseases. Therefore, searching for novel regulatory elements of endothelial activation is necessary to design improved therapies for inflammatory disorders. Here, we describe a comprehensive methodology to characterize novel endothelial regulators that can modify leukocyte trafficking during inflammation.
06:49
Using Eye Movements to Evaluate the Cognitive Processes Involved in Text Comprehension
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Cited by 138 •
2014
The present article describes how to use eye tracking methodologies to study the cognitive processes involved in text comprehension. Descriptions of eye tracking equipment, how to develop experimental stimuli, and procedural recommendations are included. The information presented can be applied to most any study using verbal stimuli.
12:29
Rat Mesentery Exteriorization: A Model for Investigating the Cellular Dynamics Involved in Angiogenesis
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Cited by 19 •
2012
This article describes a simple model for stimulating angiogenesis in the rat mesentery. The model produces dramatic increases in capillary sprouting, vascular area and vascular density over a relatively short time course in a tissue that allows en face visualization of entire microvascular networks down to the single cell level.
FAQs
Shared decision-making combines clinical evidence and professional expertise with the patient’s preferences, experiences, and priorities. The clinician contributes knowledge about available care, while the patient helps identify which option best fits their circumstances and needs. This approach makes treatment selection collaborative rather than solely professional-led, improving the relevance and acceptability of the chosen intervention.
Patient experiences can reveal which outcomes are meaningful in everyday life, rather than leaving evaluation focused only on outcomes selected by professionals. Integrating these priorities helps investigators assess whether an intervention addresses concerns that matter to the people receiving it. In clinical research, this can make findings more responsive to patient needs and strengthen their real-world value.
Clear communication allows patients to understand the decisions, evidence, and research activities in which they are being asked to participate. It also gives them a meaningful way to express experiences, preferences, and priorities. When communication supports exchange rather than one-way explanation, patient perspectives can be incorporated systematically into care choices and research planning.
Patients can contribute during research co-design, the conduct of a study, and its evaluation. Their priorities may help shape the intervention, study approach, and outcomes considered important, while their experiences can inform assessment of the finished work. Involving patients across these stages keeps the research connected to practical needs rather than limiting input to a single point.
Patient input during study development can help investigators create studies that are more responsive and acceptable to the people they aim to involve. When the design reflects patient experiences and priorities, the study may become more relevant to prospective participants and easier to sustain. This can support recruitment and retention, both of which influence the practical success of clinical research.
Clinical findings are more useful when they address outcomes and priorities that matter to patients. By connecting professional expertise and clinical evidence with patient perspectives, involvement can highlight whether an intervention is acceptable and relevant in practice. This connection helps research remain aligned with real-world needs and supports interpretation of its value beyond the study setting.