Non-destructive Analysis
Non-destructive Analysis - Related Videos
08:24
Introduction to the Ultrasound Targeted Microbubble Destruction Technique
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Cited by 19 •
2011
Ultrasound Targeted Microbubble Destruction (UTMD) can be used to direct site-specific delivery of bioactive molecules, including therapeutic genes, to target organs accessible to ultrasound, such as the heart and liver1-6.
01:12
Non-destructive Tests for Concrete Strength
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2024
The rebound hammer test, also known as the Schmidt hammer test, is a non-destructive technique for evaluating the hardness of concrete and, indirectly, the strength of concrete. It operates on the principle that the rebound of a spring-driven mass from a concrete surface correlates to the surface's hardness. The device comprises a mass within a tubular housing, a spring mechanism, and a plunger that strikes the concrete. Upon release, the energy imparted to the mass by the spring causes it to...
09:24
Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products
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Cited by 2 •
2017
A simple and non-destructive technique that measures the average content of drug substances in formulated drug products containing fluorine using low-field fluorine-19 (19F) time-domain (TD) nuclear magnetic resonance (NMR) is presented here. The technique can be applied to the development and manufacturing of drugs in the pharmaceutical industry.
11:34
Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography
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Cited by 7 •
2017
This method aims at locating vertical subsurface defects. Here, we couple a laser with a spatial light modulator and trigger its video input to heat a sample surface deterministically with two anti-phased modulated lines while acquiring highly resolved thermal images. The defect position is retrieved from evaluating thermal wave interference minima.
10:13
Non-Destructive Evaluation of Regional Cell Density Within Tumor Aggregates Following Drug Treatment
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Cited by 8 •
2022
The present protocol develops an image-based technique for rapid, non-destructive, and label-free regional cell density and viability measurement within 3D tumor aggregates. Findings revealed a cell-density gradient, with higher cell densities in core regions than outer layers in developing aggregates and predominantly peripheral cell death in HER2+ aggregates treated with Trastuzumab.
FAQs
Hidden defects appear as changes in the response of the inspected object to an applied energy source or sensing field. Those changes can reflect geometry, material properties, or irregularities such as cracks, corrosion, voids, and delamination. Engineers interpret the response rather than physically removing material, allowing the same component to remain available for use after evaluation.
The inspection method determines which physical signal is introduced and which response is interpreted. Ultrasonic waves, X-rays, heat, and electromagnetic signals can interact with an object in different ways, so each provides a particular view of changes associated with geometry, material properties, or defects. This variety lets engineering assessments address different forms of irregularity without relying on one signal alone.
Geometry and material properties are important because they can alter the measured response during evaluation. A meaningful interpretation therefore considers whether a change reflects the object's shape, its inherent material behavior, or an irregularity such as a void or delamination. Separating these influences helps engineers evaluate the significance of observed signals.
Interpretation is central because the instrument response is not itself a defect label. Engineers must relate detected changes to geometry, material properties, and possible irregularities, including cracks or corrosion. This reasoning converts sensed information into an assessment of condition, which is essential when deciding whether a component or structure requires attention.
A basic inspection sequence begins by selecting an energy source or sensing field suited to the object and the issue being investigated. The field is directed into the material, the resulting changes are observed, and those responses are interpreted in relation to geometry, material properties, or defects. The outcome is an engineering assessment without impairing future use.
Manufacturing quality control uses these evaluations to examine components as part of production, while in-service inspection checks structures during their operational life. Structural integrity assessment focuses on whether an existing system remains dependable, and predictive maintenance uses findings to identify problems early. Together, these applications support timely engineering decisions without automatically replacing the inspected item.
An engineering team can use findings to detect cracks, corrosion, voids, delamination, and other irregularities at an early stage. This information can reduce unnecessary replacement and support decisions about structural integrity, maintenance, safety, and reliability. The value is therefore not only detection, but also preserving useful components while improving management of critical systems.