Cervical Spinal Cord

The cervical spinal cord is the upper portion of the spinal cord, extending from the brainstem through the neck and serving as a vital pathway for communication between the brain and the body. It contains ascending sensory tracts, descending motor tracts, and spinal nerve roots that transmit information and coordinate movement, sensation, and autonomic functions in the neck, upper limbs, and, through lower pathways, the trunk and legs. In medicine, understanding its anatomy supports neurological examination, magnetic resonance imaging, surgical planning, and diagnosis of conditions such as cervical spinal cord injury, compression, tumors, and degenerative disease. Damage in this region can impair limb function, breathing, and mobility, making accurate assessment clinically essential.

Cervical Spinal Cord - Related Videos

Research

JoVE Journal - Neuroscience
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Diffusion Imaging in the Rat Cervical Spinal Cord

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Cited by 10 •

2015

The goal of this protocol is to obtain high-quality diffusion weighted magnetic resonance imaging (DWI) of the rat spinal cord for noninvasive characterization of tissue microstructure. This protocol describes optimizations of the MRI sequence, radiofrequency coil, and analysis methods to enable DWI images free from artifacts.

Research

JoVE Journal - Medicine

A Contusive Model of Unilateral Cervical Spinal Cord Injury Using the Infinite Horizon Impactor

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Cited by 46 •

2012

A reliable and repeatable way to produce a cervical unilateral spinal cord injury using the Infinite Horizon impactor is described. The method takes advantage of a custom designed frame and clamp to stabilize the spine. The standardized procedure and biomechanical injury parameters result in sufficient and sustained injuries.

A Murine Model of Cervical Spinal Cord Injury to Study Post-lesional Respiratory Neuroplasticity

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Cited by 16 •

2014

Respiratory failure is the leading cause of death following a cervical spinal cord injury. Having a reproducible, quantifiable, and reliable pre-clinical animal model of respiratory failure induced by a partial cervical injury will help to understand the subsequent respiratory and non-respiratory neuroplasticity and allow testing putative repair strategies.

Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats

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Cited by 55 •

2012

We describe two tactile sensory testing methods for acute or chronic periods of spinal cord injury in rats. These validated procedures can detect the development and maintenance of allodynia-like sensations.

Research

JoVE Journal - Medicine
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A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury

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Cited by 20 •

2015

Vertebral stabilization is necessary for minimizing variability, and for producing consistent experimental spinal cord injuries. Using a customized stabilizing apparatus in conjunction with the NYU/MASCIS impactor device, we have demonstrated here the proper equipment and procedure for generating reproducible hemi-contusive cervical (C5) spinal cord injuries in adult rats.

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