Vascular Reconstruction

Vascular reconstruction is a group of surgical and endovascular procedures that repair, replace, or reroute damaged or diseased blood vessels to restore adequate circulation. Surgeons may remove obstructed segments, join vessel ends with sutures, or use prosthetic or biological grafts; minimally invasive approaches can deploy stents or stent-grafts to support the vessel from within. These procedures treat conditions such as arterial occlusion, aneurysms, traumatic vascular injury, and some congenital abnormalities. By re-establishing blood flow and protecting downstream tissues from ischemia, vascular reconstruction supports limb preservation, organ function, and recovery while advancing complex vascular and transplant surgery.

Vascular Reconstruction - Related Videos

Research

JoVE Journal - Biology

Three-dimensional Reconstruction of the Vascular Architecture of the Passive CLARITY-cleared Mouse Ovary

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Cited by 12 •

2017

Here we present an adaptation of the passive CLARITY and 3D reconstruction method for visualization of the ovarian vasculature and follicular capillaries in intact mouse ovaries.

A Training and Testing System for Performing Vascular Reconstruction In Vitro

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2019

Here we present a training and testing system where a trainee can complete manual vascular reconstruction in vitro individually using a magnetic anchoring technique. The system can also be used to test the quality of reconstruction.

Visualization of Vascular and Parenchymal Regeneration after 70% Partial Hepatectomy in Normal Mice

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Cited by 3 •

2016

Tools used for visualizing vascular regeneration require methods for contrasting the vascular trees. This film demonstrated a delicate injection technique used to achieve optimal contrasting of the vascular trees and illustrate the potential benefits resulting from a detailed analysis of the resulting specimen using µCT and histological serial sections.

Vascular Reconstruction with the Cuff Technique in Mouse Orthotopic Liver Transplantation

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Cited by 3 •

2023

This protocol provides technical information for vessel reconstruction using the cuff technique in mouse orthotopic liver transplantation.

A Modified Heterotopic Swine Hind Limb Transplant Model for Translational Vascularized Composite Allotransplantation (VCA) Research

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Cited by 34 •

2013

Vascularized Composite Allotransplantations (VCA) have become a clinical reality. However, broad clinical application of VCA is limited by chronic multi-drug immunosuppression. The authors present a reliable and reproducible large animal model to translate novel immunomodulatory strategies that can minimize or potentially eliminate the need of immunosuppression in VCA.

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