Counterbalance System

A counterbalance system is a mechanical support that offsets the weight and pull of attached equipment, allowing controlled movement while reducing force on the subject or apparatus. In neuroscience experiments, it uses an opposing load, such as an adjustable weight, spring, or suspended arm, to balance cables, tubing, or recording hardware so that downward force and torque remain low as the subject moves. This arrangement helps preserve natural behavior, improves the stability of neural recording and stimulation setups, and limits mechanical artifacts caused by cable drag or sudden tension, supporting more reliable measurements in freely moving preparations.

Counterbalance System - Related Videos

Research

JoVE Journal - Biology
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Assembly, Loading, and Alignment of an Analytical Ultracentrifuge Sample Cell

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Cited by 21 •

2009

The analytical ultracentrifuge (AUC) sample cell holds sample and reference buffer and during experiments and is exposed to high vacuum and rotor speeds up to 60,000 rpm. This video will demonstrate the rigorous attention to detail necessary for assembly, loading and alignment of this very important component of an AUC experiment.

Education

JoVE Core - Chemistry

Common Ion Effect

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2020

Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide: This solubility equilibrium may be shifted left by the addition of either silver(I) or iodide ions, resulting in...

Research

JoVE Journal - Biochemistry
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Protein Complex Affinity Capture from Cryomilled Mammalian Cells

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Cited by 37 •

2016

Here we describe protocols to disrupt mammalian cells by solid-state milling at a cryogenic temperature, produce a cell extract from the resulting cell powder, and isolate protein complexes of interest by affinity capture upon antibody-coupled micron-scale paramagnetic beads.

Within-subjects Repeated-measures Design

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2023

Source: Laboratories of Gary Lewandowski, Dave Strohmetz, and Natalie Ciarocco—Monmouth University A within-subjects, or repeated-measures, design is an experimental design where all the participants receive every level of the treatment, i.e., every independent variable. For example, in a candy taste test, the researcher would want every participant to taste and rate each type of candy. This video demonstrates a within-subjects experiment (i.e., one where there is an independent variable with...

Nuclear Stability

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2020

Protons and neutrons, collectively called nucleons, are packed together tightly in a nucleus. With a radius of about 10−15 meters, a nucleus is quite small compared to the radius of the entire atom, which is about 10−10 meters. Nuclei are extremely dense compared to bulk matter, averaging 1.8 × 1014 grams per cubic centimeter. If the earth’s density were equal to the average nuclear density, the earth’s radius would be only about 200 meters. To hold positively charged protons together in the...

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