Micro Led Stimulator

A micro LED stimulator is a miniaturized device that uses light-emitting diodes to deliver precisely controlled illumination for investigating and modulating neural activity. Driven by electrical signals, its small LEDs emit selected wavelengths near or within neural tissue, where the light can activate genetically introduced light-sensitive proteins and control specific neurons with high spatial and temporal precision. In neuroscience, micro LED stimulators support optogenetic studies of neural circuits, behavior, and neurological disease. Their compact design can enable localized, programmable stimulation in freely moving or experimentally constrained subjects, advancing research on brain function and informing the development of targeted neuromodulation technologies.

Micro Led Stimulator - Related Videos

Research

JoVE Journal - Neuroscience

Using Affordable LED Arrays for Photo-Stimulation of Neurons

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Cited by 7 •

2011

Adult-born neurons expressing ChR2 can be manipulated in slice electrophysiological preparations in order to examine their contribution towards the function of olfactory neural circuits.

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

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Cited by 3 •

2013

We have developed an automated cell culture and interrogation platform for micro-scale cell stimulation experiments. The platform offers simple, versatile, and precise control in cultivating and stimulating small populations of cells, and recovering lysates for molecular analyses. The platform is well suited to studies that use precious cells and/or reagents.

Research

JoVE Journal - Biology
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How to Culture, Record and Stimulate Neuronal Networks on Micro-electrode Arrays (MEAs)

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Cited by 86 •

2010

This protocol provides the necessary information for setting up, caring for, recording from and electrically stimulating cultures on MEAs. In vitro networks provide a means for asking physiologically relevant questions at the network and cellular levels leading to a better understanding of brain function and dysfunction.

Research

JoVE Journal - Neuroscience
Free Sample

Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays

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Cited by 4 •

2017

Mouse neuronal cells cultured on multi-electrode arrays display an increase in response following electrical stimulation. This protocol demonstrates how to culture neurons, how to record activity, and how to establish a protocol to train the networks to respond to patterns of stimulation.

Combining Transcranial Magnetic Stimulation and fMRI to Examine the Default Mode Network

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Cited by 17 •

2010

In this article, we examine the methodology and considerations relevant to the combination of TMS and fMRI to examine the effects of brain stimulation on the default network.

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