W. M. Keck Observatory

The W. M. Keck Observatory is an astronomical facility in Hawai‘i that operates two of the world’s largest optical and infrared telescopes, making it a major instrument for observing faint and distant objects. Each telescope’s 10-meter primary mirror uses 36 hexagonal segments that work together, while adaptive optics measure atmospheric distortion and rapidly adjust a deformable mirror to sharpen images. These capabilities support research on exoplanets, stellar and galactic evolution, supermassive black holes, and the expansion of the universe. By combining high light-gathering power with spectroscopy, imaging, and precise measurements, the observatory helps physicists test models of how cosmic structures form and change.

W. M. Keck Observatory - Related Videos

Research

JoVE Journal - Biology

Analysis of Motility Patterns of Stentor During and After Oral Apparatus Regeneration Using Cell Tracking

0 Views •

Cited by 1 •

2021

We present a protocol for the characterization of motility and behavior of a population of hundred micron- to millimeter-sized cells using brightfield microscopy and cell tracking. This assay reveals that Stentor coeruleus transitions through four behaviorally distinct phases when regenerating a lost oral apparatus.

Whole-body Mass Spectrometry Imaging by Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR-MALDESI)

0 Views •

Cited by 19 •

2016

A mass spectrometry imaging (MSI) source operated at atmospheric pressure was developed by coupling mid-infrared laser desorption and electrospray post-ionization. Exogenous ice matrix was used as the energy-absorbing matrix to facilitate resonant desorption of tissue-related material. This manuscript provides a step-by-step protocol for performing IR-MALDESI MSI of whole-body neonatal mouse.

Simple Method for Fluorescence DNA In Situ Hybridization to Squashed Chromosomes

0 Views •

Cited by 73 •

2015

Here, we present a simple method for performing fluorescence DNA in situ hybridization (DNA ISH) to visualize repetitive heterochromatic sequences on slide-mounted chromosomes. The method requires minimal reagents and it is versatile for use with short or long probes, different tissues, and detection with fluorescence or non-fluorescence-based signals.

Research

JoVE Journal - Biology
Free Sample

Reconstituting and Characterizing Actin-Microtubule Composites with Tunable Motor-Driven Dynamics and Mechanics

0 Views •

Cited by 1 •

2022

This paper presents protocols for engineering and characterizing tunable three-dimensional composite networks of co-entangled actin filaments and microtubules. Composites undergo active restructuring and ballistic motion, driven by myosin II and kinesin motors, and are tuned by the relative concentrations of actin, microtubules, motor proteins, and passive crosslinkers.

Research

JoVE Journal - Medicine
Free Sample

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

0 Views •

Cited by 13 •

2014

Brain damage resulting from cerebral ischemia may be non-invasively imaged and studied in rats using pre-clinical positron emission tomography coupled with the injectable radioactive probe, 18F-fluorodeoxyglucose. Further, the use of modern software tools that include volume of interest (VOI) brain templates dramatically increase the quantitative information gleaned from these studies.

View All Results

FAQs

Related Topics