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Overvågning af signalresponser på målet i larvezebrafisk - Z-REX afslører præcise mekanismer for elektrofile lægemidler og metabolitter
Dissection and Lipid Droplet Staining of Oenocytes in Drosophila Larvae
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Overvågning af signalresponser på målet i larvezebrafisk - Z-REX afslører præcise mekanismer for elektrofile lægemidler og metabolitter

Article DOI: 10.3791/64846-v • 05:28 min • June 2nd, 2023
June 2nd, 2023 •
1, 1, 2, 3, 4, 1
1Swiss Federal Institute of Technology Lausanne (EPFL), 2Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 3Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, 4University of Lausanne (UNIL)

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Zebrafisk målrettet mod reaktive elektrofiler og oxidanter (Z-REX) er en kemisk biologisk baseret metode til undersøgelse af reaktiv småmolekylesignalering. Denne teknik kan anvendes til levende fisk i forskellige udviklingsstadier. Her kobler vi standardanalyser i zebrafisk med Z-REX til signalvejsanalyse.

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Biologi nr. 196
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