Temporal Bone Surgery

Temporal bone surgery is a group of otologic and skull-base procedures that treats disease or injury within the dense bone surrounding the ear, facial nerve, inner ear, and major blood vessels. Surgeons use carefully planned approaches and high-speed drilling to remove abnormal tissue while identifying and preserving critical structures, with techniques such as mastoidectomy tailored to the anatomy and clinical goal. These operations can address chronic ear disease, cholesteatoma, tumors, trauma, and cerebrospinal fluid leaks, helping control infection, protect hearing and facial movement, and provide access to lesions that require multidisciplinary skull-base care.

Temporal Bone Surgery - Related Videos

Research

JoVE Journal - Developmental Biology
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Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

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2017

The segmentation clock drives oscillatory gene expression across the pre-somitic mesoderm (PSM). Dynamic Notch activity is key to this process. We use imaging and computational analyses to extract temporal dynamics from spatial expression data to demonstrate that Delta ligand and Notch receptor expression oscillate in the vertebrate PSM.

Research

JoVE Journal - Medicine

Extracting the Cochlea from a Human Temporal Bone: A Cadaveric Protocol

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2023

This article presents a reliable method for extracting the human cochlea from the cadaver temporal bone by drill-out while following distinct anatomical landmarks.

Education

JoVE Science Education - Basic Biology

Considerations for Rodent Surgery

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2016

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN The Guide for the Care and Use of Laboratory Animals1 dictates that rodent survival surgery be performed aseptically. Aseptic technique utilizes specific practices that minimize the contamination of the surgical site, including patient preparation, surgeon preparation, sterilization of instruments and other supplies, and the use of a clean and controlled environment. Presurgical planning,...

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

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2022

This article describes a technique for rapid human temporal bone sectioning that utilizes a microsaw with twin diamond blades to generate thin slices for rapid decalcification and analysis of temporal bone immunohistochemistry.

Models of Bone Metastasis

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Cited by 115 •

2012

Animal models are frequently utilized to study cancer metastasis to bone. In this protocol we will describe two common methods of tumor inoculation for bone metastasis studies and briefly describe some of the analyses utilized to monitor and quantify these models.

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