Carlos S. Subauste Department of Pathology Case Western Reserve University Biography Publications Institution JoVE Articles Carlos S. Subauste has not added a biography. If you are Carlos S. Subauste and would like to personalize this page please email our Author Liaison for assistance. Publications Advanced Glycation End Products Upregulate CD40 in Human Retinal Endothelial and Müller Cells: Relevance to Diabetic Retinopathy Cells. Feb, 2024 | Pubmed ID: 38474393 Animal Models for Toxoplasma Gondii Infection Current Protocols. Sep, 2023 | Pubmed ID: 37695167 CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression Investigative Ophthalmology & Visual Science. Jun, 2023 | Pubmed ID: 37294707 Disruption of Retinal Inflammation and the Development of Diabetic Retinopathy in Mice by a CD40-derived Peptide or Mutation of CD40 in Müller Cells Diabetologia. Dec, 2022 | Pubmed ID: 35920844 CD40 Expressed in Endothelial Cells Promotes Upregulation of ICAM-1 But Not Pro-Inflammatory Cytokines, NOS2 and P2X7 in the Diabetic Retina Investigative Ophthalmology & Visual Science. Sep, 2021 | Pubmed ID: 34546322 Recent Advances in the Roles of Autophagy and Autophagy Proteins in Host Cells During Infection and Potential Therapeutic Implications Frontiers in Cell and Developmental Biology. 2021 | Pubmed ID: 34179003 A Cell-penetrating CD40-TRAF2,3 Blocking Peptide Diminishes Inflammation and Neuronal Loss After Ischemia/reperfusion FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2021 | Pubmed ID: 33675257 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th Edition) Autophagy. Feb, 2021 | Pubmed ID: 33634751 The CD40-ATP-P2X Receptor Pathway: Cell to Cell Cross-Talk to Promote Inflammation and Programmed Cell Death of Endothelial Cells Frontiers in Immunology. 2019 | Pubmed ID: 31921199 Toxoplasma Gondii Induces Prolonged Host Epidermal Growth Factor Receptor Signalling to Prevent Parasite Elimination by Autophagy: Perspectives for in Vivo Control of the Parasite Cellular Microbiology. Oct, 2019 | Pubmed ID: 31290228 Interplay Between , Autophagy, and Autophagy Proteins Frontiers in Cellular and Infection Microbiology. 2019 | Pubmed ID: 31119109 CD40 in Endothelial Cells Restricts Neural Tissue Invasion by Toxoplasma Gondii Infection and Immunity. Aug, 2019 | Pubmed ID: 31109947 Epidermal Growth Factor Receptor Promotes Cerebral and Retinal Invasion by Toxoplasma Gondii Scientific Reports. Jan, 2019 | Pubmed ID: 30679495 CD40, a Novel Inducer of Purinergic Signaling: Implications to the Pathogenesis of Experimental Diabetic Retinopathy Vision (Basel, Switzerland). Aug, 2017 | Pubmed ID: 31740645 Toxoplasma Gondii Induces FAK-Src-STAT3 Signaling During Infection of Host Cells That Prevents Parasite Targeting by Autophagy PLoS Pathogens. Oct, 2017 | Pubmed ID: 29036202 Loss of CD40 Attenuates Experimental Diabetes-induced Retinal Inflammation but Does Not Protect Mice from Electroretinogram Defects Visual Neuroscience. Jan, 2017 | Pubmed ID: 28965505 CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy Diabetes. Feb, 2017 | Pubmed ID: 27474370 Ligation of CD40 in Human Müller Cells Induces P2X7 Receptor-Dependent Death of Retinal Endothelial Cells Investigative Ophthalmology & Visual Science. Nov, 2016 | Pubmed ID: 27893093 Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity Against Toxoplasma Gondii in Macrophages Infection and Immunity. Sep, 2016 | Pubmed ID: 27354443 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 CD40-TRAF Signaling Upregulates CX3CL1 and TNF-α in Human Aortic Endothelial Cells but Not in Retinal Endothelial Cells PloS One. 2015 | Pubmed ID: 26710229 Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium The Journal of Biological Chemistry. Nov, 2015 | Pubmed ID: 26468292 Atg5 but Not Atg7 in Dendritic Cells Enhances IL-2 and IFN-γ Production by Toxoplasma Gondii-reactive CD4+ T Cells Microbes and Infection. Apr, 2015 | Pubmed ID: 25578385 Blockade of CD40-TRAF2,3 or CD40-TRAF6 is Sufficient to Inhibit Pro-inflammatory Responses in Non-haematopoietic Cells Immunology. Jan, 2015 | Pubmed ID: 25051892 Proinflammatory Responses Induced by CD40 in Retinal Endothelial and Müller Cells Are Inhibited by Blocking CD40-Traf2,3 or CD40-Traf6 Signaling Investigative Ophthalmology & Visual Science. Dec, 2014 | Pubmed ID: 25477319 CD40 Promotes the Development of Early Diabetic Retinopathy in Mice Diabetologia. Oct, 2014 | Pubmed ID: 25015056 Toxoplasma Gondii-induced Activation of EGFR Prevents Autophagy Protein-mediated Killing of the Parasite PLoS Pathogens. 2013 | Pubmed ID: 24367261 Modulation of Retinal Müller Cells by Complement Receptor C5aR Investigative Ophthalmology & Visual Science. Dec, 2013 | Pubmed ID: 24265019 The Protein Kinase Double-stranded RNA-dependent (PKR) Enhances Protection Against Disease Cause by a Non-viral Pathogen PLoS Pathogens. 2013 | Pubmed ID: 23990781 CD40 Induces Anti-Toxoplasma Gondii Activity in Nonhematopoietic Cells Dependent on Autophagy Proteins Infection and Immunity. Jun, 2013 | Pubmed ID: 23509150 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy Autophagy. Apr, 2012 | Pubmed ID: 22966490 CD40 and Tumour Necrosis Factor-α Co-operate to Up-regulate Inducuble Nitric Oxide Synthase Expression in Macrophages Immunology. Feb, 2012 | Pubmed ID: 22044243 Review of the Series "Disease of the Year 2011: Toxoplasmosis" Pathophysiology of Toxoplasmosis Ocular Immunology and Inflammation. Oct, 2011 | Pubmed ID: 21970661 Chemokine (C-C Motif) Receptor 5 -2459 Genotype in Patients Receiving Highly Active Antiretroviral Therapy: Race-specific Influence on Virologic Success The Journal of Infectious Diseases. Jul, 2011 | Pubmed ID: 21673041 Photoreceptor Cells Constitutively Express Functional TLR4 Journal of Neuroimmunology. Jan, 2011 | Pubmed ID: 20801528 The CD40-autophagy Pathway is Needed for Host Protection Despite IFN-Γ-dependent Immunity and CD40 Induces Autophagy Via Control of P21 Levels PloS One. Dec, 2010 | Pubmed ID: 21217818 HIV-1 Inhibits Autophagy in Bystander Macrophage/monocytic Cells Through Src-Akt and STAT3 PloS One. Jul, 2010 | Pubmed ID: 20661303 Autophagy in Immunity Against Toxoplasma Gondii Current Topics in Microbiology and Immunology. 2009 | Pubmed ID: 19802569 Autophagy As an Antimicrobial Strategy Expert Review of Anti-infective Therapy. Aug, 2009 | Pubmed ID: 19681702 Identification of Primary Retinal Cells and Ex Vivo Detection of Proinflammatory Molecules Using Flow Cytometry Molecular Vision. Jul, 2009 | Pubmed ID: 19626134 CD40 and the Immune Response to Parasitic Infections Seminars in Immunology. Oct, 2009 | Pubmed ID: 19616968 CD40, Autophagy and Toxoplasma Gondii Memorias Do Instituto Oswaldo Cruz. Mar, 2009 | Pubmed ID: 19430652 CD40 Mediates Retinal Inflammation and Neurovascular Degeneration Journal of Immunology (Baltimore, Md. : 1950). Dec, 2008 | Pubmed ID: 19050292 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy in Higher Eukaryotes Autophagy. Feb, 2008 | Pubmed ID: 18188003 Role of CD40-dependent Down-regulation of CD154 in Impaired Induction of CD154 in CD4(+) T Cells from HIV-1-infected Patients Journal of Immunology (Baltimore, Md. : 1950). Feb, 2007 | Pubmed ID: 17237414 CD40-TRAF6 and Autophagy-dependent Anti-microbial Activity in Macrophages Autophagy. 2007 | Pubmed ID: 17224624 CD40 Induces Macrophage Anti-Toxoplasma Gondii Activity by Triggering Autophagy-dependent Fusion of Pathogen-containing Vacuoles and Lysosomes The Journal of Clinical Investigation. Sep, 2006 | Pubmed ID: 16955139 A Simplified Method for Isolation and Culture of Retinal Pigment Epithelial Cells from Adult Mice Alyssa Hubal1,2, Amelia Pfaff2, Sarah Vos2, Mala Upadhyay3, Vera Bonilha3, Carlos S. Subauste1,2 1Department of Pathology, Case Western Reserve University, 2Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, 3Cole Eye Institute, Ophthalmic Research, Cleveland Clinic JoVE 66921 신경과학
A Simplified Method for Isolation and Culture of Retinal Pigment Epithelial Cells from Adult Mice Alyssa Hubal1,2, Amelia Pfaff2, Sarah Vos2, Mala Upadhyay3, Vera Bonilha3, Carlos S. Subauste1,2 1Department of Pathology, Case Western Reserve University, 2Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, 3Cole Eye Institute, Ophthalmic Research, Cleveland Clinic JoVE 66921 신경과학