William B. Chrisler Biological Sciences Division Pacific Northwest National Laboratory Biography Publications Institution JoVE Articles William B. Chrisler has not added a biography. If you are William B. Chrisler and would like to personalize this page please email our Author Liaison for assistance. Publications Automated Coupling of Nanodroplet Sample Preparation with Liquid Chromatography-Mass Spectrometry for High-Throughput Single-Cell Proteomics Analytical Chemistry. 08, 2020 | Pubmed ID: 32639140 An Improved Boosting to Amplify Signal with Isobaric Labeling (iBASIL) Strategy for Precise Quantitative Single-cell Proteomics Molecular & Cellular Proteomics : MCP. 05, 2020 | Pubmed ID: 32127492 Physiologically Based Pharmacokinetic Modeling of Salivary Concentrations for Noninvasive Biomonitoring of 2,4-Dichlorophenoxyacetic Acid (2,4-D) Toxicological Sciences : an Official Journal of the Society of Toxicology. 12, 2019 | Pubmed ID: 31550007 High-Throughput Single Cell Proteomics Enabled by Multiplex Isobaric Labeling in a Nanodroplet Sample Preparation Platform Analytical Chemistry. 10, 2019 | Pubmed ID: 31509397 Stable Acinar Progenitor Cell Model Identifies Treacle-Dependent Radioresistance Radiation Research. 08, 2019 | Pubmed ID: 31141469 Forfeiting the Priority Effect: Turnover Defines Biofilm Community Succession The ISME Journal. 07, 2019 | Pubmed ID: 30886318 Carrier-Assisted Single-Tube Processing Approach for Targeted Proteomics Analysis of Low Numbers of Mammalian Cells Analytical Chemistry. 01, 2019 | Pubmed ID: 30557009 Impact of Lithiated Cobalt Oxide and Phosphate Nanoparticles on Rainbow Trout Gill Epithelial Cells Nanotoxicology. 12, 2018 | Pubmed ID: 30451563 Evaluation of Non-invasive Biomonitoring of 2,4-Dichlorophenoxyacetic Acid (2,4-D) in Saliva Toxicology. 12, 2018 | Pubmed ID: 30118794 Spatially Resolved Proteome Profiling of <200 Cells from Tomato Fruit Pericarp by Integrating Laser-Capture Microdissection with Nanodroplet Sample Preparation Analytical Chemistry. Sep, 2018 | Pubmed ID: 30118597 Spatially Resolved Proteome Mapping of Laser Capture Microdissected Tissue with Automated Sample Transfer to Nanodroplets Molecular & Cellular Proteomics : MCP. Sep, 2018 | Pubmed ID: 29941660 Proteomic Analysis of Single Mammalian Cells Enabled by Microfluidic Nanodroplet Sample Preparation and Ultrasensitive NanoLC-MS Angewandte Chemie (International Ed. in English). Sep, 2018 | Pubmed ID: 29797682 Publisher Correction: Influences of Organic Carbon Speciation on Hyporheic Corridor Biogeochemistry and Microbial Ecology Nature Communications. 03, 2018 | Pubmed ID: 29515121 Influences of Organic Carbon Speciation on Hyporheic Corridor Biogeochemistry and Microbial Ecology Nature Communications. 02, 2018 | Pubmed ID: 29422537 Phenotypic Responses to Interspecies Competition and Commensalism in a Naturally-derived Microbial Co-culture Scientific Reports. 01, 2018 | Pubmed ID: 29321512 Fluctuation Localization Imaging-based Fluorescence in Situ Hybridization (fliFISH) for Accurate Detection and Counting of RNA Copies in Single Cells Nucleic Acids Research. 01, 2018 | Pubmed ID: 29040675 Predicting Species-Resolved Macronutrient Acquisition During Succession in a Model Phototrophic Biofilm Using an Integrated 'Omics Approach Frontiers in Microbiology. 2017 | Pubmed ID: 28659875 Indirect Interspecies Regulation: Transcriptional and Physiological Responses of a Cyanobacterium to Heterotrophic Partnership MSystems. Mar-Apr, 2017 | Pubmed ID: 28289730 Phycobilisome Truncation Causes Widespread Proteome Changes in Synechocystis Sp. PCC 6803 PloS One. 2017 | Pubmed ID: 28253354 A Flexible Microbial Co-culture Platform for Simultaneous Utilization of Methane and Carbon Dioxide from Gas Feedstocks Bioresource Technology. Mar, 2017 | Pubmed ID: 28092828 Cells Respond to Distinct Nanoparticle Properties with Multiple Strategies As Revealed by Single-Cell RNA-Seq ACS Nano. Nov, 2016 | Pubmed ID: 27788331 Unlocking the Constraints of Cyanobacterial Productivity: Acclimations Enabling Ultrafast Growth MBio. Jul, 2016 | Pubmed ID: 27460798 Conservation of Protein Abundance Patterns Reveals the Regulatory Architecture of the EGFR-MAPK Pathway Science Signaling. 07, 2016 | Pubmed ID: 27405981 Groundwater-surface Water Mixing Shifts Ecological Assembly Processes and Stimulates Organic Carbon Turnover Nature Communications. Apr, 2016 | Pubmed ID: 27052662 Lipopolysaccharide Density and Structure Govern the Extent and Distance of Nanoparticle Interaction with Actual and Model Bacterial Outer Membranes Environmental Science & Technology. Sep, 2015 | Pubmed ID: 26207769 The Effect of Low Dose Ionizing Radiation on Homeostasis and Functional Integrity in an Organotypic Human Skin Model Mutation Research. May, 2015 | Pubmed ID: 25839759 Sensitive Targeted Quantification of ERK Phosphorylation Dynamics and Stoichiometry in Human Cells Without Affinity Enrichment Analytical Chemistry. Jan, 2015 | Pubmed ID: 25517423 Inference of Interactions in Cyanobacterial-heterotrophic Co-cultures Via Transcriptome Sequencing The ISME Journal. Nov, 2014 | Pubmed ID: 24781900 Phototrophic Biofilm Assembly in Microbial-mat-derived Unicyanobacterial Consortia: Model Systems for the Study of Autotroph-heterotroph Interactions Frontiers in Microbiology. 2014 | Pubmed ID: 24778628 In Situ Molecular Imaging of a Hydrated Biofilm in a Microfluidic Reactor by ToF-SIMS The Analyst. Apr, 2014 | Pubmed ID: 24571001 Organelle-specific Activity-based Protein Profiling in Living Cells Angewandte Chemie (International Ed. in English). Mar, 2014 | Pubmed ID: 24505022 Live Cell Chemical Profiling of Temporal Redox Dynamics in a Photoautotrophic Cyanobacterium ACS Chemical Biology. Jan, 2014 | Pubmed ID: 24168666 Intracellular Accumulation Dynamics and Fate of Zinc Ions in Alveolar Epithelial Cells Exposed to Airborne ZnO Nanoparticles at the Air-liquid Interface Nanotoxicology. Dec, 2013 | Pubmed ID: 24289294 Annexin A2 Modulates Radiation-sensitive Transcriptional Programming and Cell Fate Radiation Research. Jan, 2013 | Pubmed ID: 23148505 Integrated Experimental and Model-based Analysis Reveals the Spatial Aspects of EGFR Activation Dynamics Molecular BioSystems. Nov, 2012 | Pubmed ID: 22952062 Cell Type-dependent Gene Transcription Profile in a Three-dimensional Human Skin Tissue Model Exposed to Low Doses of Ionizing Radiation: Implications for Medical Exposures Environmental and Molecular Mutagenesis. May, 2012 | Pubmed ID: 22351304 Delivery of MicroRNA-10b with Polylysine Nanoparticles for Inhibition of Breast Cancer Cell Wound Healing Breast Cancer : Basic and Clinical Research. 2012 | Pubmed ID: 22259248 Aerosolized ZnO Nanoparticles Induce Toxicity in Alveolar Type II Epithelial Cells at the Air-liquid Interface Toxicological Sciences : an Official Journal of the Society of Toxicology. Feb, 2012 | Pubmed ID: 21964423 Inhibition of ERK Oscillations by Ionizing Radiation and Reactive Oxygen Species Molecular Carcinogenesis. Jun, 2011 | Pubmed ID: 21557328 ISDD: A Computational Model of Particle Sedimentation, Diffusion and Target Cell Dosimetry for in Vitro Toxicity Studies Particle and Fibre Toxicology. Nov, 2010 | Pubmed ID: 21118529 Three-dimensional Culture Conditions Lead to Decreased Radiation Induced Cytotoxicity in Human Mammary Epithelial Cells Mutation Research. May, 2010 | Pubmed ID: 20211636 Basic Fibroblast Growth Factor Regulates Persistent ERK Oscillations in Premalignant but Not Malignant JB6 Cells The Journal of Investigative Dermatology. May, 2010 | Pubmed ID: 20016498 Rapid and Sustained Nuclear-cytoplasmic ERK Oscillations Induced by Epidermal Growth Factor Molecular Systems Biology. 2009 | Pubmed ID: 19953086 HER/ErbB Receptor Interactions and Signaling Patterns in Human Mammary Epithelial Cells BMC Cell Biology. Oct, 2009 | Pubmed ID: 19878579 Cellular Dichotomy Between Anchorage-independent Growth Responses to BFGF and TPA Reflects Molecular Switch in Commitment to Carcinogenesis Molecular Carcinogenesis. Nov, 2009 | Pubmed ID: 19526458 Lysophosphatidic Acid-induced ERK Activation and Chemotaxis in MC3T3-E1 Preosteoblasts Are Independent of EGF Receptor Transactivation Journal of Cellular Physiology. Jun, 2009 | Pubmed ID: 19189345 MRNA-targeted Fluorescent in Situ Hybridization (FISH) of Gram-negative Bacteria Without Template Amplification or Tyramide Signal Amplification Journal of Microbiological Methods. Dec, 2007 | Pubmed ID: 17949838 A Paracrine Signal Mediates the Cell Transformation Response to Low Dose Gamma Radiation in JB6 Cells Molecular Carcinogenesis. May, 2005 | Pubmed ID: 15800926 Modulation of JB6 Mouse Epidermal Cell Transformation Response by the Prostaglandin F2alpha Receptor Molecular Carcinogenesis. Dec, 2002 | Pubmed ID: 12489107 Carrier-assisted One-pot Sample Preparation for Targeted Proteomics Analysis of Small Numbers of Human Cells Kendall Martin1, Tong Zhang1, Pengfei Zhang2, William B. Chrisler1, Fillmore L. Thomas3, Fen Liu4, Tao Liu1, Wei-Jun Qian1, Richard D. Smith1, Tujin Shi1 1Biological Sciences Division, Pacific Northwest National Laboratory, 2NHC Key Laboratory of Cancer Proteomics, Department of Oncology, Xiangya Hospital, Central South University, 3Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, 4Department of Critical Care Medicine, The First Affiliated Hospital of Nanchang University JoVE 61797 생화학
Carrier-assisted One-pot Sample Preparation for Targeted Proteomics Analysis of Small Numbers of Human Cells Kendall Martin1, Tong Zhang1, Pengfei Zhang2, William B. Chrisler1, Fillmore L. Thomas3, Fen Liu4, Tao Liu1, Wei-Jun Qian1, Richard D. Smith1, Tujin Shi1 1Biological Sciences Division, Pacific Northwest National Laboratory, 2NHC Key Laboratory of Cancer Proteomics, Department of Oncology, Xiangya Hospital, Central South University, 3Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, 4Department of Critical Care Medicine, The First Affiliated Hospital of Nanchang University JoVE 61797 생화학