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Chapter 3
Fundamentals of Chemistry

What is Matter?
The substance of the universe—from a grain of sand to a star—is called matter. Scientists define matter as anything that occupies space…
The Periodic Table and Organismal Elements
Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of…
Atomic Structure
The Greek philosopher Democritus proposed that everything on Earth is made up of tiny particles called atomos, Greek for "indivisible," from…
Chemical Symbols
A chemical symbol is an abbreviation that is used to indicate an element or an atom of an element. For example, the symbol for mercury is Hg. We use…
Atomic Number and Mass Number
The number of protons in the nucleus of an atom is its atomic number (Z). This is the defining trait of an element. Its value determines the identity…
Atomic Weight
Protons and neutrons have approximately the same mass, about 1.67 × 10-24 grams. Scientists arbitrarily define this amount of mass as one atomic…
Isotopes and Radioisotopes
In the early 1900s, English chemist Frederick Soddy realized that an element could have atoms with different masses that were chemically…
Electron Behavior
Electrons are negatively charged subatomic particles attracted to and orbit around the positively-charged nucleus of an atom. They reside in spaces…
Introduction to Chemical Bonds
Chemical Bonds The electrons of the outermost energy level determine the energetic stability of the atom and its tendency to form chemical bonds with…
Ionic Bonds
When atoms gain or lose electrons to achieve a more stable electron configuration they form ions. Ionic bonds are electrostatic attractions between…
Covalent Bonds
Overview When two atoms share electrons to complete their valence shells, they create a covalent bond. An atom's electronegativity—the…
Hydrogen Bonds
A hydrogen bond is formed when a weakly positive hydrogen atom already bonded to one electronegative atom (for example, the oxygen in the water…
Ions, Molecules, and Compounds
Ions - When an atom participates in a chemical reaction that results in the donation or acceptance of one or more electrons, the atom becomes…
States of Matter
Solids, liquids, and gases are the three states of matter commonly found on Earth. A solid is rigid and possesses a definite shape. A liquid flows…
Colloids and Suspensions
Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as…
Introduction to Chemical Reactions
All chemical reactions begin with a reactant, the general term for one or more substances entering the reaction. Sodium and chloride ions, for…
Types of Chemical Reactions: Anabolic and Catabolic
The first law of thermodynamics holds that energy can neither be created nor destroyed—it can only change form. An organism's essential…
Types of Chemical Reactions: Exchange and Reversible
An exchange reaction is a chemical reaction in which both synthesis and decomposition occur, chemical bonds are both formed and broken, and chemical…
Energy Transfer in Chemical Reactions
Chemical reactions require sufficient energy to cause the matter to collide with enough precision and force that old chemical bonds can be broken and…
Factors Influencing the Rate of Chemical Reactions
A variety of factors influence the rate of chemical reactions. For a chemical reaction to happen, atoms must collide with enough energy to overcome…
Acids, Bases And Neutralization Reactions
Acids and bases play several important roles in biology. The pH of a biological system can significantly impact the function of biological molecules,…
The Bioconjugation and Radiosynthesis of <sup>89</sup>Zr-DFO-labeled Antibodies
The exceptional affinity, specificity, and selectivity of antibodies make them extraordinarily attractive vectors for tumor-targeted PET…
Measuring Lactase Enzymatic Activity in the Teaching Lab
Understanding how enzymes work, and relating this to real life examples, is critical to a wide range of undergraduate degrees in the biological and…
Synthesis and Characterization of Supramolecular Colloids
Control over colloidal assembly is of utmost importance for the development of functional colloidal materials with tailored structural and mechanical…

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