Nozzle Deposition

Nozzle deposition is a fabrication method that dispenses a material through a shaped opening to create controlled lines, droplets, or three-dimensional structures. In bioengineering, a pneumatic, piston, or screw-driven system forces a bioink through a nozzle, while computer-guided motion positions the material layer by layer; viscosity, pressure, nozzle diameter, and deposition speed determine feature resolution and cell survival. Deposited materials may solidify through cooling, chemical crosslinking, or other curing processes to form scaffolds and tissue-like architectures. The technique supports 3D bioprinting, regenerative medicine, drug delivery, and biological model development, although balancing printability with biomaterial and cellular requirements remains essential.

Nozzle Deposition - Related Videos

Education

JoVE Science Education - Engineering

Nozzle Analysis: Variations in Mach Number and Pressure Along a Converging and a Converging-diverging Nozzle

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2023

Source: Shreyas Narsipur, Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC A nozzle is a device that is commonly used to accelerate or decelerate flow by virtue of its varying cross-section. Nozzles are widely used in aerospace propulsion systems. In rockets, propellant that is ejected from the chamber is accelerated through a nozzle to create a reaction force that propels the system. In jet engines, a nozzle is used to transform energy from a high-pressure...

Research

JoVE Journal - Engineering
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Measuring Spray Droplet Size from Agricultural Nozzles Using Laser Diffraction

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Cited by 30 •

2016

We present protocols to be used in the measurement of spray droplet size from agricultural nozzles used in both aerial and ground based agrochemical applications. These methods presented were developed to provide consistent and repeatable droplet size data both inter- and intra-laboratory, when using laser diffraction systems.

Alginate Encapsulation of Pluripotent Stem Cells Using a Co-axial Nozzle

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Cited by 14 •

2015

We established a method of encapsulating pluripotent stem cells (PS cells) into alginate hydrogel capsules using a co-axial nozzle. This prevents cells from aggregating excessively and limits the shear stress experienced by cells in suspension culture. The technique is applicable to the mass production of PS cells as well as research on stem cell niche.

Formation of Thick Dense Yttrium Iron Garnet Films Using Aerosol Deposition

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Cited by 7 •

2015

This report describes the use of a custom-built system to perform aerosol deposition of thick films of yttrium iron garnet onto sapphire substrates at RT. The deposited films are characterized using scanning electron microscopy, profilometry, and ferromagnetic resonance to give a representative overview of the capabilities of the technique.

Production and Aerosol-Based Deposition of Bacillus subtilis Spores

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2025

Source: Fuchs, F. M., et al. Investigating the Detrimental Effects of Low Pressure Plasma Sterilization on the Survival of Bacillus subtilis Spores Using Live Cell Microscopy. J. Vis. Exp. (2017)This video demonstrates the production, purification, and aerosol-based deposition of Bacillus subtilis spores to create a uniform monolayer, enabling downstream applications such as microscopy-based analysis of spore germination, viability, or stress response.

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