Colonic Mobilization

Colonic mobilization is a surgical technique that frees segments of the colon from their peritoneal attachments, allowing the bowel to be repositioned safely during abdominal procedures. It typically involves incising the lateral peritoneal reflections and dissecting along the relatively avascular plane behind the colon while protecting the mesentery, blood vessels, ureters, and adjacent organs. In medicine, this maneuver provides length and reach for colorectal resection, anastomosis, stoma creation, and management of some traumatic or obstructive conditions. By improving exposure and reducing tension on reconstructed bowel, colonic mobilization supports precise dissection and may help achieve secure surgical reconstruction.

Colonic Mobilization - Related Videos

Research

JoVE EoE - Neurophysiology

Electrophysiological Recording from Colonic Afferent Nerves in an Ex Vivo Rat Colon

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2025

This video demonstrates a method to record the activity of colonic afferent nerves in an ex-vivo rat colon, cannulated at both ends and infused with saline to increase intraluminal pressure. As pressure increases, the nerve signal rises, indicating its stimulation.

Education

JoVE Science Education - Chemistry

Electrophoretic Mobility Shift Assay (EMSA)

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2023

The electrophoretic mobility shift assay (EMSA) is a biochemical procedure used to elucidate binding between proteins and nucleic acids. In this assay a radiolabeled nucleic acid and test protein are mixed. Binding is determined via gel electrophoresis which separates components based on mass, charge, and conformation. This video shows the concepts of EMSA and a general procedure, including gel and protein preparation, binding, electrophoresis, and detection. Applications covered in this video...

Mobile Marketing

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2024

As consumers increasingly rely on smartphones and other mobile devices for browsing, communication, and shopping, mobile marketing has become essential in today's digital world. Brands must adjust their strategies to engage users where they spend most of their time, which is on mobile screens. Understanding mobile user behavior is crucial for successful mobile marketing. Mobile users typically interact with their devices briefly and frequently throughout the day. They prefer content that is...

A Murine Model of Group B Streptococcus Vaginal Colonization

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Cited by 64 •

2016

The purpose of this protocol is to imitate human group B Streptococcus (GBS) vaginal colonization in a murine model. This method may be used to investigate host immune responses and bacterial factors contributing to GBS vaginal persistence, as well as to test therapeutic strategies.

Generation of Mouse Proximal Colon Loop Model: A Surgical Procedure to Generate Proximal Colon Loop and Measure Intestinal Permeability by Detection of Fluorescent Markers in Serum Following Intraluminal Injection

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2025

In this video, we describe a surgical procedure to generate mouse proximal colon loop or pcLoop segment followed by intraluminal injection of fluorescent markers into the segment to study the intestinal epithelial permeability.

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