Electrode Trajectory Planning

Electrode trajectory planning is the process of designing a safe, precise path for placing a neural electrode within the brain or another anatomical target, balancing access to the intended site with protection of surrounding tissue. Using medical imaging, anatomical models, and stereotactic coordinates, clinicians select an entry point and calculate the electrode’s angle, depth, and orientation while accounting for structures such as blood vessels, ventricles, and functional brain regions. In medicine, this planning supports procedures including deep brain stimulation and intracranial recording, helping improve targeting accuracy, reduce surgical risk, and produce more reliable treatment or diagnostic data.

Electrode Trajectory Planning - Related Videos

Research

JoVE Journal - Medicine
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A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

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Cited by 19 •

2016

We describe the steps to use our custom designed software for image integration, visualization and planning in epilepsy surgery.

Research

JoVE Journal - Biology

Trajectory Data Analyses for Pedestrian Space-time Activity Study

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Cited by 15 •

2013

A suite of spatiotemporal processing methods are presented to analyze human trajectory data, such as that collected using a GPS device, for the purpose of modeling pedestrian space-time activities.

Education

JoVE Core - Calculus

Orthogonal Trajectories

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2026

Orthogonal trajectories describe the geometric relationship between two families of curves that intersect each other at right angles. One illustrative case involves a family of parabolas that open sideways along the x-axis. These curves share a common shape but differ by a scaling parameter, resulting in a set of curves that all pass through the origin and widen at different rates.Determining Orthogonal TrajectoriesTo identify the orthogonal trajectories for these parabolas, the first step...

Studying Cell Rolling Trajectories on Asymmetric Receptor Patterns

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Cited by 3 •

2011

We describe a protocol to observe and analyze cell rolling trajectories on asymmetric receptor-patterned substrates. The resulting data are useful for engineering of receptor-patterned substrates for label-free cell separation and analysis.

Electroporation of the Hindbrain to Trace Axonal Trajectories and Synaptic Targets in the Chick Embryo

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Cited by 9 •

2013

How neuronal networks are established in the embryonic brain is a fundamental question in developmental neurobiology. Here we combined an electroporation technique with novel genetic tools, such as Cre/Lox–plasmids and PiggyBac-mediated DNA transposition system in the avian hindbrain to label dorsal interneurons and track their axonal projections and synaptic targets at various developmental stages.

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