Surface Curve Fitting

Surface curve fitting is a mathematical and computational method for representing measured data as a continuous surface, making complex spatial patterns easier to analyze in medicine. It works by selecting a model, such as a polynomial or spline, and adjusting its parameters to minimize differences between the fitted surface and observed coordinates, often using least-squares optimization. In medical imaging, this approach can approximate anatomical boundaries, smooth noisy measurements, quantify shape and curvature, and support visualization or comparison of structures across patients and time. Reliable fitting depends on appropriate model complexity and data quality, since overfitting can obscure clinically meaningful patterns.

Surface Curve Fitting - Related Videos

Education

JoVE Core - Calculus

Calculus with Parametric Curves: Surface Areas

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2026

A parametric curve is a description of a path in the plane where both the x and y coordinates are functions of a single parameter, typically denoted t. When such a curve is revolved about an external axis lying in the same plane, it generates a surface of revolution in three dimensions. The surface area of this rotated shape depends fundamentally on two aspects: the geometry of the original curve and how far it lies from the chosen axis of rotation.A torus is a classical surface of revolution...

Bending of Curved Members - Neutral Surface

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2024

In curved beams, unlike straight beams, the stress distribution across the cross-section is not uniform due to the beam's curvature. This non-uniformity arises because the neutral axis, where stress is zero, does not align with the centroid of the section. In a curved beam, the strain varies along the section as a function of the distance from the neutral axis. Consider the curved member described in the previous lesson. According to Hooke's law, which relates stress to strain within the...

Hydrostatic Pressure Force on a Curved Surface

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2025

Hydrostatic pressure on curved surfaces is a fundamental concept in fluid mechanics with broad applications in the civil engineering field. When fluid is in contact with a curved surface, as in a reservoir, dam, or storage tank, it exerts pressure that varies in magnitude and direction along the curved surface. To assess the total hydrostatic force exerted by the fluid on a curved structure, engineers typically isolate the fluid volume adjacent to the surface and analyze the forces acting on...

Research

JoVE Journal - Biology
Free Sample

A Quantitative Fitness Analysis Workflow

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Cited by 25 •

2012

Quantitative Fitness Analysis (QFA) is a complementary series of experimental and computational methods for estimating microbial culture fitnesses. QFA estimates the effect of genetic mutations, drugs or other applied treatments on microbe growth. Experiments scaling from focussed analysis of single cultures to thousands of parallel cultures can be designed.

Calibration Curves

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2023

Source: Laboratory of Dr. B. Jill Venton - University of Virginia Calibration curves are used to understand the instrumental response to an analyte and predict the concentration in an unknown sample. Generally, a set of standard samples are made at various concentrations with a range than includes the unknown of interest and the instrumental response at each concentration is recorded. For more accuracy and to understand the error, the response at each concentration can be repeated so an error...

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