Common Cold

The common cold is a usually self-limited viral infection of the upper respiratory tract and a major focus of pharmacology because its symptoms drive widespread medication use. Respiratory viruses, especially rhinoviruses and seasonal coronaviruses, infect nasal and throat epithelial cells, while the host inflammatory response produces congestion, rhinorrhea, sore throat, cough, and sometimes fever. Pharmacologic management therefore targets symptoms rather than the virus itself, using agents such as analgesics, antipyretics, decongestants, antihistamines, or cough medicines according to the patient’s needs and safety considerations. Understanding the illness helps distinguish supportive treatment from inappropriate antibiotic use and guides evaluation of combination cold products.

Common Cold - Related Videos

Research

JoVE Journal - Medicine

Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels

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2025

Here, we present a protocol to establish a long-term liver cold storage and transplantation model in Daurian ground squirrel (DGS), which has been technically challenging in standard rodent models.

Education

JoVE Science Education - Basic Biology

Working with Hot and Cold Sources

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2023

Source: Robert M. Rioux & Suprita Jharimune, Pennsylvania State University, University Park, PA Working with extreme temperatures, both high and low, is an integral part of many laboratory operations. For many, mentioning a laboratory instantly evokes the mental picture of a Bunsen burner. Bunsen burners and hot plates are used extensively in small and large operations in research laboratories and industries, thus making it necessary for all users to be aware of their safe handling...

Common Ion Effect

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2020

Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide: This solubility equilibrium may be shifted left by the addition of either silver(I) or iodide ions, resulting in...

Regulating Temperature in the Lab: Preserving Samples Using Cold

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2023

Preservation of laboratory samples, specimens, and reagents using extreme cold is routinely performed in biomedical research labs. This video will discuss some of the methods for keeping laboratory samples cold and will explain the correct cooling method to use for each experimental requirement. For example, cooling agents, such as ice and dry ice, are typically used when keeping samples cold during experiments. This video discusses the physical properties of the most commonly used cooling...

Responses to Heat and Cold Stress

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2020

Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes. When the environmental dynamics fall out of the optimal limit for a given species, changes in metabolism and functioning occur – and this is defined as stress. Plants respond to stress by initiating changes in gene expression - leading to adjustments in plant...

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