Live Model
Live Model - Related Videos
02:19
Intradermal Immunization with Live Attenuated Sporozoites in a Mouse Model
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2025
This video demonstrates an assay for immunizing a mouse model with live attenuated sporozoites. The radiation-attenuated Plasmodium sporozoites are injected into the dorsal side of the mouse's ear. After injections at multiple locations on both ears, the mouse is allowed to recover.
11:21
Co-culture Models of Pseudomonas aeruginosa Biofilms Grown on Live Human Airway Cells
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Cited by 48 •
2010
This paper describes different methods of growing Pseudomonas aeruginosa biofilms on cultured human airway epithelial cells. These protocols can be adapted to study different aspects of biofilm formation, including visualization of the biofilm, staining of the biofilm, measuring the colony forming units (CFU) of the biofilm, and studying biofilm cytotoxicity.
06:10
Live Imaging of Mouse Secondary Palate Fusion
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Cited by 11 •
2017
Here, we present a protocol for live imaging of mouse secondary palate fusion using confocal microscopy. This protocol can be used in combination with a variety of fluorescent reporter mouse lines, and with pathway inhibitors for mechanistic insight. This protocol can be adapted for live imaging in other developmental systems.
08:26
MAME Models for 4D Live-cell Imaging of Tumor: Microenvironment Interactions that Impact Malignant Progression
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Cited by 43 •
2012
We have developed 3D coculture models for live-cell imaging in real-time of interactions among breast tumor cells and other cells in their microenvironment that impact progression to an invasive phenotype. These models can serve as preclinical screens for drugs to target paracrine-induced proteolytic, chemokine/cytokine and kinase pathways implicated in invasiveness.
05:41
In Vitro Ovule Cultivation for Live-cell Imaging of Zygote Polarization and Embryo Patterning in Arabidopsis thaliana
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Cited by 27 •
2017
This manuscript describes an in vitro ovule cultivation method that enables live-cell imaging of Arabidopsis zygotes and embryos. This method is utilized to visualize the intracellular dynamics during zygote polarization and the cell fate specification in developing embryos.
FAQs
The observer first needs to attend to the demonstrated action, because attention supports encoding, the mental representation of what was seen. Reproduction then depends on motivation, ability, and suitable conditions. Thus, observing a performance does not by itself ensure imitation; those factors help determine whether the encoded behavior is performed.
Reinforcement can affect whether an observer is likely to imitate a demonstrated behavior, while perceived similarity between observer and model can also influence imitation. Attention determines what enters encoding, whereas motivation helps determine whether the observer attempts performance. Together, these variables provide a framework for studying social influence and behavior change.
Even when an observer has encoded the demonstrated behavior, performance may not occur if the person lacks the ability to reproduce it or if suitable conditions are absent. Motivation adds another requirement, because the observer must have reason to perform. This distinction helps psychologists separate learning from observable behavior.
During a live modeling session, a real person demonstrates the target behavior while another individual observes. The observer attends to the actions and encodes what was demonstrated. Researchers or practitioners then consider motivation, ability, and suitable conditions when evaluating whether the observer reproduces the behavior.
In psychology, live models support classroom instruction, clinical interventions, and social-skills training. They also appear in laboratory studies of observational learning and social influence. These settings let researchers or practitioners examine how people acquire behaviors, while applied programs use demonstrations to support behavior change and skill acquisition.
Studies using live models can examine whether reinforcement, attention, and perceived similarity affect imitation. They can also explore how observers acquire skills, respond to social influence, and change behavior after watching a demonstration. The resulting observations connect the model’s performance with the observer’s encoding, motivation, ability, and actual reproduction.