Confocal Microscopy for Sharp Cell Images

Confocal microscopy is an advanced imaging method used to capture sharp fluorescence images. Its main advantage is that it blocks out-of-focus light from the sample with pinholes. That helps produce high-resolution images with strong contrast.

Unlike a standard optical microscope, a confocal micr...

A confocal laser scanning microscope or CLSM uses a laser and a series of pinholes to section a sample into thin optical slices. These slices can be compiled to reconstruct a sharp, detailed image.

Unlike traditional fluorescence microscopes where the entire field is illuminated, CLSM uses a laser beam to restrict the excitation of fluoro...