Immune Pathways

Immune pathways are interconnected molecular and cellular processes that detect threats, coordinate defense, and maintain tissue homeostasis. In biology, innate immune receptors recognize pathogen-associated or damage-associated signals, activating intracellular signaling cascades that induce cytokines, inflammation, and antimicrobial responses; adaptive pathways use antigen presentation to activate specialized lymphocytes and generate immunological memory. Studying these pathways clarifies how immune cells communicate and distinguish harmful agents from healthy tissue. Their analysis supports research into infection, vaccination, autoimmune disease, cancer, and therapeutic strategies that modify immune activity.

Immune Pathways - Related Videos

Education

JoVE Core - Biology

C4 Pathway and CAM

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2019

Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy. C4 Pathway The C4 pathway is used by plants such as...

What is the Immune System?

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2019

Overview The immune system comprises diverse biological structures and processes that protect the body from disease. These processes can be classified into innate and adaptive immunity. To work effectively, the immune system needs to detect pathogens by distinguishing the body’s own structures from foreign elements. If this determination fails, autoimmune diseases occur in which the immune system reacts against the body’s own tissue. The Innate Immune System Acts Fast and Non-specifically

Research

JoVE EoE - Immunodiagnostics

Measuring Immune-Induced Inhibition of Seedling Growth

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2025

This video demonstrates the seedling growth inhibition assay in the Arabidopsis thaliana plant. The impact of increased concentration of immune peptide elicitor on seedling growth is determined.

Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network

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Cited by 30 •

2016

We have established a technique for the isolation, phenotypic characterization and functional analysis of immune cells from murine gingiva.

Humoral Immune Responses

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2019

Overview The humoral immune response, also known as the antibody-mediated immune response, targets pathogens circulating in “humors,” or extracellular fluids, such as blood and lymph. Antibodies target invading pathogens for destruction via multiple defense mechanisms, including neutralization, opsonization, and activation of the complement system. Patients that are impaired in the production of antibodies suffer from severe and frequent infections by common pathogens and unusual pathogens. B...

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